%0 Journal Article %1 FitzGerald:2000:Genet-Epidemiol:10723105 %A FitzGerald, P E %A Knuiman, M W %D 2000 %J Genet Epidemiol %K CategoricalDataAnalysis CorrelatedData review statistics %N 3 %P 193-202 %R 10.1002/(SICI)1098-2272(200003)18:3<193::AID-GEPI1>3.0.CO;2-W %T Use of conditional and marginal odds-ratios for analysing familial aggregation of binary data %U https://www.ncbi.nlm.nih.gov/pubmed/10723105 %V 18 %X We propose a method for measuring familial aggregation of binary outcomes that incorporates unconditional, i.e., marginal, odds-ratios, for measuring association between outcomes within generations while using conditional odds-ratios to measure association between generations. This method may be used together with marginal odds-ratio models to explore the strength of association between individuals within a generation while accounting for the outcomes of predecessors. Interpretation of resulting odds-ratios is straightforward and a number of features of the method are discussed. An example, using smoking status data from Busselton Health Study families, is used to illustrate our approach.

@article{FitzGerald:2000:Genet-Epidemiol:10723105, abstract = {We propose a method for measuring familial aggregation of binary outcomes that incorporates unconditional, i.e., marginal, odds-ratios, for measuring association between outcomes within generations while using conditional odds-ratios to measure association between generations. This method may be used together with marginal odds-ratio models to explore the strength of association between individuals within a generation while accounting for the outcomes of predecessors. Interpretation of resulting odds-ratios is straightforward and a number of features of the method are discussed. An example, using smoking status data from Busselton Health Study families, is used to illustrate our approach.}, added-at = {2019-11-20T09:53:32.000+0100}, author = {FitzGerald, P E and Knuiman, M W}, biburl = {https://www.bibsonomy.org/bibtex/20e1c7860085c67017a673ab0d4a47102/jkd}, description = {Use of conditional and marginal odds-ratios for analysing familial aggregation of binary data. - PubMed - NCBI}, doi = {10.1002/(SICI)1098-2272(200003)18:3<193::AID-GEPI1>3.0.CO;2-W}, interhash = {b9eef3bb71d8da1aca7b42d31e198490}, intrahash = {0e1c7860085c67017a673ab0d4a47102}, journal = {Genet Epidemiol}, keywords = {CategoricalDataAnalysis CorrelatedData review statistics}, month = mar, number = 3, pages = {193-202}, pmid = {10723105}, timestamp = {2019-11-20T09:55:38.000+0100}, title = {Use of conditional and marginal odds-ratios for analysing familial aggregation of binary data}, url = {https://www.ncbi.nlm.nih.gov/pubmed/10723105}, volume = 18, year = 2000 }