As the global epidemic of obesity and type two diabetes in children and adults continues to be a major challenge to public health, an intriguing possible ‘off-target’ effect of the rotavirus vaccine and association with a reduction in the incidence of Type 1 diabetes, has been reported in JAMA Paediatrics. An Australian study from a team in Melbourne, JAMA Pediatr 2019;173(3):280-282. doi: 10.1001/jamapediatrics.2018.4578) and is the first report of epidemiological evidence of this possible and fascinating association.. To read the full article, log in using your MPFT NHS OpenAthens details.