%0 Journal Article %1 citeulike:471084 %A Wortberg, Monika %A Kreissig, Sabine B. %A Jones, Geoffrey %A Rocke, David M. %A Hammock, Bruce D. %D 1995 %J Analytica Chimica Acta %K immunoassay statistic analysis %N 3 %P 339--352 %R 10.1016/0003-2670(94)00651-2 %T An immunoarray for the simultaneous determination of multiple triazine herbicides %U http://www.sciencedirect.com/science/article/B6TF4-3YKKPWK-8V/2/87f91d1d4cc70ea2d51ce8740c368cd5 %V 304 %X An immunochemical method for simultaneous analysis of cross-reacting analytes is presented. We demonstrate the general principle using triazine herbicides as the model system. The analysis is based on a combination of individual enzyme immunoassays (immunoarray) for triazine herbicides using antibodies with different cross-reactivity patterns towards the selected analytes. The assay signals obtained can be mathematically evaluated to estimate concentrations of each analyte out of a ternary or quaternary mixture. The mathematical model utilizes an extension of the empirical four parameter log-logistic fit. Using mono- and polyclonal antibodies it was possible to quantify the four analytes atrazine, simazine, cyanazine, and prometon in the low to sub-ppb range simultaneously.

@article{citeulike:471084, abstract = {An immunochemical method for simultaneous analysis of cross-reacting analytes is presented. We demonstrate the general principle using triazine herbicides as the model system. The analysis is based on a combination of individual enzyme immunoassays (immunoarray) for triazine herbicides using antibodies with different cross-reactivity patterns towards the selected analytes. The assay signals obtained can be mathematically evaluated to estimate concentrations of each analyte out of a ternary or quaternary mixture. The mathematical model utilizes an extension of the empirical four parameter log-logistic fit. Using mono- and polyclonal antibodies it was possible to quantify the four analytes atrazine, simazine, cyanazine, and prometon in the low to sub-ppb range simultaneously.}, added-at = {2006-07-07T01:10:50.000+0200}, author = {Wortberg, Monika and Kreissig, Sabine B. and Jones, Geoffrey and Rocke, David M. and Hammock, Bruce D.}, biburl = {https://www.bibsonomy.org/bibtex/2922ceda83d4708d7dbd0b60967309705/biblio24}, citeulike-article-id = {471084}, doi = {10.1016/0003-2670(94)00651-2}, interhash = {21d6984d1eeed64e69556dd3aa5edf7c}, intrahash = {922ceda83d4708d7dbd0b60967309705}, journal = {Analytica Chimica Acta}, keywords = {immunoassay statistic analysis}, month = {April}, number = 3, pages = {339--352}, priority = {2}, timestamp = {2006-07-07T01:10:50.000+0200}, title = {An immunoarray for the simultaneous determination of multiple triazine herbicides}, url = {http://www.sciencedirect.com/science/article/B6TF4-3YKKPWK-8V/2/87f91d1d4cc70ea2d51ce8740c368cd5}, volume = 304, year = 1995 }