%0 Journal Article %1 golden_positive_2004 %A Golden, Matthew R %A Hughes, James P %A Cles, Linda E %A Crouse, Karen %A Gudgel, Katherine %A Hu, Jinxin %A Swenson, Paul D %A Stamm, Walter E %A Handsfield, H Hunter %D 2004 %J Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America %K Acid Amplification Diagnostic Female, Gonorrhea, Humans, Neisseria Nucleic Predictive Prevalence, Routine, Sensitivity Specificity Techniques, Tests, Value and gonorrhoeae, of %N 9 %P 1387--1390 %R 10.1086/424880 %T Positive predictive value of Gen-Probe APTIMA Combo 2 testing for Neisseria gonorrhoeae in a population of women with low prevalence of N. gonorrhoeae infection %U http://www.ncbi.nlm.nih.gov/pubmed/15494917 %V 39 %X We collected specimens from women who tested positive for Neisseria gonorrhoeae using the Gen-Probe APTIMA Combo 2 (AC2), and we performed confirmatory tests using a nucleic acid amplification test (NAAT) that targets alternate gonococcal nucleic acid sequences. Among 59,664 specimens, 280 (0.47\%) had positive results using AC2; 265 of these specimens were tested using the confirmatory NAAT, of which 258 yielded positive results (positive predictive value, 97.4\%; 95\% confidence interval, 95.1\%-98.8\%). Routine confirmatory testing of specimens with positive AC2 gonorrhea test results is not indicated.

@article{golden_positive_2004, abstract = {We collected specimens from women who tested positive for Neisseria gonorrhoeae using the {Gen-Probe} {APTIMA} Combo 2 {(AC2),} and we performed confirmatory tests using a nucleic acid amplification test {(NAAT)} that targets alternate gonococcal nucleic acid sequences. Among 59,664 specimens, 280 (0.47\%) had positive results using {AC2;} 265 of these specimens were tested using the confirmatory {NAAT,} of which 258 yielded positive results (positive predictive value, 97.4\%; 95\% confidence interval, 95.1\%-98.8\%). Routine confirmatory testing of specimens with positive {AC2} gonorrhea test results is not indicated.}, added-at = {2011-03-11T10:05:34.000+0100}, author = {Golden, Matthew R and Hughes, James P and Cles, Linda E and Crouse, Karen and Gudgel, Katherine and Hu, Jinxin and Swenson, Paul D and Stamm, Walter E and Handsfield, H Hunter}, biburl = {https://www.bibsonomy.org/bibtex/2a21b042bdc55cd03d449dc473f711da9/jelias}, doi = {10.1086/424880}, interhash = {199a30cf4102e617b2e335eb5b94d9b6}, intrahash = {a21b042bdc55cd03d449dc473f711da9}, issn = {1537-6591}, journal = {Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America}, keywords = {Acid Amplification Diagnostic Female, Gonorrhea, Humans, Neisseria Nucleic Predictive Prevalence, Routine, Sensitivity Specificity Techniques, Tests, Value and gonorrhoeae, of}, month = nov, note = {{PMID:} 15494917}, number = 9, pages = {1387--1390}, timestamp = {2011-03-11T10:06:02.000+0100}, title = {Positive predictive value of {Gen-Probe} {APTIMA} Combo 2 testing for Neisseria gonorrhoeae in a population of women with low prevalence of N. gonorrhoeae infection}, url = {http://www.ncbi.nlm.nih.gov/pubmed/15494917}, volume = 39, year = 2004 }