%0 Journal Article %1 zlamy_immunogenicity_2011 %A Zlamy, Manuela %A Elias, Johannes %A Vogel, Ulrich %A Frosch, Matthias %A Jeller, Verena %A Cortina, Gerard %A Jungraithmayr, Therese %A Prelog, Martina %D 2011 %J Vaccine %K Children Gutachtersystem Habilitation Meningococcus_C_vaccination Transplantation je {SBA}_titers %N 37 %P 6163--6166 %R 10.1016/j.vaccine.2011.06.033 %T Immunogenicity of conjugate Meningococcus C vaccine in pediatric solid organ transplant recipients %U http://www.sciencedirect.com/science/article/pii/S0264410X11008978 %V 29 %X The present study was aimed to evaluate the immunogenicity of a single dose of conjugate Meningococcus C (Men C) vaccine by analyzing the serum bactericidal antibody (SBA) titers in 10 pediatric solid organ transplant (SOT) patients. Four patients showed a delayed immune response after 1 month, but all patients demonstrated an increase of SBA titers after vaccination. A significant decrease of SBA titers was seen after 6 months. However, all patients maintained protective SBA titers (≥1:8) despite rapidly waning titers. For patients with significantly decreasing titers, a booster dose may be discussed with close monitoring of SBA titers over time.

@article{zlamy_immunogenicity_2011, abstract = {The present study was aimed to evaluate the immunogenicity of a single dose of conjugate Meningococcus C {(Men} C) vaccine by analyzing the serum bactericidal antibody {(SBA)} titers in 10 pediatric solid organ transplant {(SOT)} patients. Four patients showed a delayed immune response after 1 month, but all patients demonstrated an increase of {SBA} titers after vaccination. A significant decrease of {SBA} titers was seen after 6 months. However, all patients maintained protective {SBA} titers (≥1:8) despite rapidly waning titers. For patients with significantly decreasing titers, a booster dose may be discussed with close monitoring of {SBA} titers over time.}, added-at = {2011-10-20T16:39:31.000+0200}, author = {Zlamy, Manuela and Elias, Johannes and Vogel, Ulrich and Frosch, Matthias and Jeller, Verena and Cortina, Gerard and Jungraithmayr, Therese and Prelog, Martina}, biburl = {https://www.bibsonomy.org/bibtex/22c0ae8cabc6050e3a100ed9aad3e541d/ag_vogel}, doi = {10.1016/j.vaccine.2011.06.033}, interhash = {1dbfc2f8bfa67187de3e22f0c88f0aa0}, intrahash = {2c0ae8cabc6050e3a100ed9aad3e541d}, issn = {{0264-410X}}, journal = {Vaccine}, keywords = {Children Gutachtersystem Habilitation Meningococcus_C_vaccination Transplantation je {SBA}_titers}, month = aug, number = 37, pages = {6163--6166}, timestamp = {2014-02-06T18:29:18.000+0100}, title = {Immunogenicity of conjugate Meningococcus C vaccine in pediatric solid organ transplant recipients}, url = {http://www.sciencedirect.com/science/article/pii/S0264410X11008978}, volume = 29, year = 2011 }