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A comprehensive guide for managing antibiotic therapy in pediatric pneumonia

, , , , , and . World Journal of Biology Pharmacy and Health Sciences, 12 (1): 174–189 (October 2022)
DOI: 10.30574/wjbphs.2022.12.1.0167

Abstract

Pneumonia is a respiratory infection characterized by inflammation of the alveolar space and interstitial tissue of the lungs. Pneumonia has numerous potential etiologies, the most common of which is infectious and is classified according to several factors. Pneumonia is most transmitted via aspiration of airborne pathogens but may also result from the aspiration of stomach contents. The most likely causal pathogens can be narrowed down based on the patient’s age, immune status, and where the infection was acquired. Pathogens that commonly affect the pediatric population often differ from those seen in adults. Typical pneumonia manifests with, fever, sudden onset of malaise, and a productive cough. On auscultation, crackles and bronchial breath sounds are audible. Atypical pneumonia manifests with the gradual onset of unproductive cough, dyspnea, and extrapulmonary manifestations. Diagnosis is based on history and exam. In some cases, supportive information is obtained through lab investigations and imaging reports. Management consists of empiric antibiotic treatment and supportive measures.

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