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oposSOM: R-package for high-dimensional portraying of genome-wide expression landscapes on bioconductor

, , and . Bioinformatics, 31 (19): 3225-3227 (October 2015)
DOI: 10.1093/bioinformatics/btv342

Abstract

Comprehensive analysis of genome-wide molecular data challenges bioinformatics methodology in terms of intuitive visualization with single-sample resolution, biomarker selection, functional information mining and highly granular stratification of sample classes. oposSOM combines those functionalities making use of a comprehensive analysis and visualization strategy based on self-organizing maps (SOM) machine learning which we call 'high-dimensional data portraying'. The method was successfully applied in a series of studies using mostly transcriptome data but also data of other OMICs realms.oposSOM is now publicly available as Bioconductor R package.wirth@izbi.uni-leipzig.deSupplementary data are available at Bioinformatics online.

Description

oposSOM: R-package for high-dimensional portraying of genome-wide expression landscapes on bioconductor. - PubMed - NCBI

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