Comprehensive analysis of genome-wide molecular data challenges bioinformatics methodology in terms of intuitive visualization with single-sample resolution, biomarker selection, functional information mining and highly granular stratification of sample classes. oposSOM combines those functionalities making use of a comprehensive analysis and visualization strategy based on self-organizing maps (SOM) machine learning which we call 'high-dimensional data portraying'. The method was successfully applied in a series of studies using mostly transcriptome data but also data of other OMICs realms.oposSOM is now publicly available as Bioconductor R package.wirth@izbi.uni-leipzig.deSupplementary data are available at Bioinformatics online.
Description
oposSOM: R-package for high-dimensional portraying of genome-wide expression landscapes on bioconductor. - PubMed - NCBI
%0 Journal Article
%1 LofflerWirth:2015:Bioinformatics:26063839
%A Löffler-Wirth, H
%A Kalcher, M
%A Binder, H
%D 2015
%J Bioinformatics
%K bioconductor fulltext mach machine-learning mustread software
%N 19
%P 3225-3227
%R 10.1093/bioinformatics/btv342
%T oposSOM: R-package for high-dimensional portraying of genome-wide expression landscapes on bioconductor
%U https://www.ncbi.nlm.nih.gov/pubmed/26063839
%V 31
%X Comprehensive analysis of genome-wide molecular data challenges bioinformatics methodology in terms of intuitive visualization with single-sample resolution, biomarker selection, functional information mining and highly granular stratification of sample classes. oposSOM combines those functionalities making use of a comprehensive analysis and visualization strategy based on self-organizing maps (SOM) machine learning which we call 'high-dimensional data portraying'. The method was successfully applied in a series of studies using mostly transcriptome data but also data of other OMICs realms.oposSOM is now publicly available as Bioconductor R package.wirth@izbi.uni-leipzig.deSupplementary data are available at Bioinformatics online.
@article{LofflerWirth:2015:Bioinformatics:26063839,
abstract = {Comprehensive analysis of genome-wide molecular data challenges bioinformatics methodology in terms of intuitive visualization with single-sample resolution, biomarker selection, functional information mining and highly granular stratification of sample classes. oposSOM combines those functionalities making use of a comprehensive analysis and visualization strategy based on self-organizing maps (SOM) machine learning which we call 'high-dimensional data portraying'. The method was successfully applied in a series of studies using mostly transcriptome data but also data of other OMICs realms.oposSOM is now publicly available as Bioconductor R package.wirth@izbi.uni-leipzig.deSupplementary data are available at Bioinformatics online.},
added-at = {2020-02-11T23:40:41.000+0100},
author = {L{\"o}ffler-Wirth, H and Kalcher, M and Binder, H},
biburl = {https://www.bibsonomy.org/bibtex/23f556a79a73e864f1cdd1fc13f910295/marcsaric},
description = {oposSOM: R-package for high-dimensional portraying of genome-wide expression landscapes on bioconductor. - PubMed - NCBI},
doi = {10.1093/bioinformatics/btv342},
interhash = {0d27a8bd150c376888fc98d502bdcb28},
intrahash = {3f556a79a73e864f1cdd1fc13f910295},
journal = {Bioinformatics},
keywords = {bioconductor fulltext mach machine-learning mustread software},
month = oct,
number = 19,
pages = {3225-3227},
pmid = {26063839},
timestamp = {2020-02-11T23:41:28.000+0100},
title = {oposSOM: R-package for high-dimensional portraying of genome-wide expression landscapes on bioconductor},
url = {https://www.ncbi.nlm.nih.gov/pubmed/26063839},
volume = 31,
year = 2015
}