%0 Journal Article %1 Elliott1983195Hgm195Aum %A Elliott, A. T. %A Dymond, D. S. %A Stone, D. L. %A Flatman, W. %A Bett, R. %A Cuninghame, J. G. %A Sims, H. E. %A Willis, H. H. %D 1983 %J Physics in Medicine and Biology %K radiation family %N 2 %P 139+ %R 10.1088/0031-9155/28/2/003 %T A 195Hgm-195Aum generator for use in first-pass nuclear angiocardiography %U http://dx.doi.org/10.1088/0031-9155/28/2/003 %V 28 %X The development of a mercury-195m/gold-195m radionuclide generator system is described, together with the results of preliminary experiments in animals and in man. The daughter radionuclide has half-life of 30.5 s with a principal gamma emission at 262 keV, ideal for use with the multicrystal camera but suitable also in conjunction with the Anger design. The half-life of the parent radionuclide is 40 h. The eluant in current use is 2.5 mM sodium cyanide, the column being stored under 2\% sodium nitrate solution when not in use to prevent radiation damage. Generators capable of delivering 550 MBq of 195 Au m in a 0.4 ml bolus have been used for first-pass nuclear angiocardiography, the half-life being long enough to permit administration via peripheral intravenous injection. The radiation dose associated with this radionuclide is much lower than that from conventional 99 Tc m -labelled radiopharmaceuticals, permitting multiple sequential studies, even on children.

@article{Elliott1983195Hgm195Aum, abstract = {The development of a mercury-195m/gold-195m radionuclide generator system is described, together with the results of preliminary experiments in animals and in man. The daughter radionuclide has half-life of 30.5 s with a principal gamma emission at 262 keV, ideal for use with the multicrystal camera but suitable also in conjunction with the Anger design. The half-life of the parent radionuclide is 40 h. The eluant in current use is 2.5 mM sodium cyanide, the column being stored under 2\% sodium nitrate solution when not in use to prevent radiation damage. Generators capable of delivering 550 MBq of 195 Au m in a 0.4 ml bolus have been used for first-pass nuclear angiocardiography, the half-life being long enough to permit administration via peripheral intravenous injection. The radiation dose associated with this radionuclide is much lower than that from conventional 99 Tc m -labelled radiopharmaceuticals, permitting multiple sequential studies, even on children.}, added-at = {2018-06-18T21:23:34.000+0200}, author = {Elliott, A. T. and Dymond, D. S. and Stone, D. L. and Flatman, W. and Bett, R. and Cuninghame, J. G. and Sims, H. E. and Willis, H. H.}, biburl = {https://www.bibsonomy.org/bibtex/26e49a25eb8283ed3f61a4407a7e6a549/pbett}, citeulike-article-id = {13693284}, citeulike-linkout-0 = {http://dx.doi.org/10.1088/0031-9155/28/2/003}, citeulike-linkout-1 = {http://iopscience.iop.org/0031-9155/28/2/003}, day = 01, doi = {10.1088/0031-9155/28/2/003}, interhash = {b31bfc1c01cb72d7e28268eb237bcee6}, intrahash = {6e49a25eb8283ed3f61a4407a7e6a549}, issn = {0031-9155}, journal = {Physics in Medicine and Biology}, keywords = {radiation family}, month = feb, number = 2, pages = {139+}, posted-at = {2015-08-03 10:04:23}, priority = {2}, timestamp = {2018-06-22T18:35:16.000+0200}, title = {A 195Hgm-195Aum generator for use in first-pass nuclear angiocardiography}, url = {http://dx.doi.org/10.1088/0031-9155/28/2/003}, volume = 28, year = 1983 }