Neuroendocrine prostate cancer is a rare entity with a poor prognosis. It can present in a pure form (small or large cell neuroendocrine carcinoma) or mixed, that is to say associated with an adenocarcinomatous contingent. Rarely diagnosed de novo, primary large cell tumors are exceptional. The development of molecular analysis tools has provided important elements for understanding the origin of this histological subtype and the signaling pathways involved. This could also help to identify diagnostic and prognostic biomarkers as well as potential molecular targets. We report here the case of a 63-year-old patient diagnosed with mixed prostate cancer with large cell neuroendocrine component at a localized stage and detail the particularities of his management.
%0 Journal Article
%1 jihane2024neuroendocrine
%A Jihane, Chouef
%A Hajar, Medyouni
%A Imane, Ouafki
%A Oumaima, Siyouri
%A Samia, Elhakym
%A Samia, Mhirech
%A Lamiae, Amaadour
%A Karima, Oualla
%A Zineb, Benbrahim
%A Samia, Arifi
%A Nawfel, Mellas
%D 2024
%J African Journal of Medicine and Pharma Research
%K adenocarcinoma surgery therapy tumor
%N 1
%P 5-8
%R https://doi.org/10.5281/zenodo.10972047
%T Neuroendocrine Prostate Tumor: A Case Report and Literature Review
%U https://africanjmpr.com/docs/2024/jan-june-2024/AJMPR-02.pdf
%V 2
%X Neuroendocrine prostate cancer is a rare entity with a poor prognosis. It can present in a pure form (small or large cell neuroendocrine carcinoma) or mixed, that is to say associated with an adenocarcinomatous contingent. Rarely diagnosed de novo, primary large cell tumors are exceptional. The development of molecular analysis tools has provided important elements for understanding the origin of this histological subtype and the signaling pathways involved. This could also help to identify diagnostic and prognostic biomarkers as well as potential molecular targets. We report here the case of a 63-year-old patient diagnosed with mixed prostate cancer with large cell neuroendocrine component at a localized stage and detail the particularities of his management.
@article{jihane2024neuroendocrine,
abstract = {Neuroendocrine prostate cancer is a rare entity with a poor prognosis. It can present in a pure form (small or large cell neuroendocrine carcinoma) or mixed, that is to say associated with an adenocarcinomatous contingent. Rarely diagnosed de novo, primary large cell tumors are exceptional. The development of molecular analysis tools has provided important elements for understanding the origin of this histological subtype and the signaling pathways involved. This could also help to identify diagnostic and prognostic biomarkers as well as potential molecular targets. We report here the case of a 63-year-old patient diagnosed with mixed prostate cancer with large cell neuroendocrine component at a localized stage and detail the particularities of his management.},
added-at = {2024-04-20T19:23:47.000+0200},
author = {Jihane, Chouef and Hajar, Medyouni and Imane, Ouafki and Oumaima, Siyouri and Samia, Elhakym and Samia, Mhirech and Lamiae, Amaadour and Karima, Oualla and Zineb, Benbrahim and Samia, Arifi and Nawfel, Mellas},
biburl = {https://www.bibsonomy.org/bibtex/272be9631cf219554dac9c69d51d6e015/ajmpr},
doi = {https://doi.org/10.5281/zenodo.10972047},
interhash = {08ffbe27d5f7e1113ee1ea311cac78f9},
intrahash = {72be9631cf219554dac9c69d51d6e015},
issn = {E-ISSN: 2992-4197; P-ISSN: 2992-4170},
journal = {African Journal of Medicine and Pharma Research },
keywords = {adenocarcinoma surgery therapy tumor},
language = {English},
month = {Jan-Jun-2024},
number = 1,
pages = {5-8},
subjectarea = {Medical Oncology},
timestamp = {2024-04-20T19:23:47.000+0200},
title = {Neuroendocrine Prostate Tumor: A Case Report and Literature Review},
url = {https://africanjmpr.com/docs/2024/jan-june-2024/AJMPR-02.pdf},
volume = 2,
year = 2024
}