The availability and utility of genome-scale metabolic reconstructions have exploded since the first genome-scale reconstruction was published a decade ago. Reconstructions have now been built for a wide variety of organisms, and have been used toward five major ends: (1) contextualization of high-throughput data, (2) guidance of metabolic engineering, (3) directing hypothesis-driven discovery, (4) interrogation of multi-species relationships, and (5) network property discovery. In this review, we examine the many uses and future directions of genome-scale metabolic reconstructions, and we highlight trends and opportunities in the field that will make the greatest impact on many fields of biology.
Description
Applications of genome-scale metabolic reconstruct... [Mol Syst Biol. 2009] - PubMed result
%0 Journal Article
%1 Oberhardt:2009:Mol-Syst-Biol:19888215
%A Oberhardt, M A
%A Palsson, B Ø
%A Papin, J A
%D 2009
%J Mol Syst Biol
%K imported proj:0915
%P 320-320
%R 10.1038/msb.2009.77
%T Applications of genome-scale metabolic reconstructions
%U http://www.ncbi.nlm.nih.gov/pubmed/19888215?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1
%V 5
%X The availability and utility of genome-scale metabolic reconstructions have exploded since the first genome-scale reconstruction was published a decade ago. Reconstructions have now been built for a wide variety of organisms, and have been used toward five major ends: (1) contextualization of high-throughput data, (2) guidance of metabolic engineering, (3) directing hypothesis-driven discovery, (4) interrogation of multi-species relationships, and (5) network property discovery. In this review, we examine the many uses and future directions of genome-scale metabolic reconstructions, and we highlight trends and opportunities in the field that will make the greatest impact on many fields of biology.
@article{Oberhardt:2009:Mol-Syst-Biol:19888215,
abstract = {The availability and utility of genome-scale metabolic reconstructions have exploded since the first genome-scale reconstruction was published a decade ago. Reconstructions have now been built for a wide variety of organisms, and have been used toward five major ends: (1) contextualization of high-throughput data, (2) guidance of metabolic engineering, (3) directing hypothesis-driven discovery, (4) interrogation of multi-species relationships, and (5) network property discovery. In this review, we examine the many uses and future directions of genome-scale metabolic reconstructions, and we highlight trends and opportunities in the field that will make the greatest impact on many fields of biology.},
added-at = {2009-11-12T00:23:05.000+0100},
author = {Oberhardt, M A and Palsson, B {\O} and Papin, J A},
biburl = {https://www.bibsonomy.org/bibtex/27422fdf700000c0011fb41dc36caf7b8/wnpxrz},
description = {Applications of genome-scale metabolic reconstruct... [Mol Syst Biol. 2009] - PubMed result},
doi = {10.1038/msb.2009.77},
interhash = {33f8b60bbee43be607b875e43df066ca},
intrahash = {7422fdf700000c0011fb41dc36caf7b8},
journal = {Mol Syst Biol},
keywords = {imported proj:0915},
pages = {320-320},
pmid = {19888215},
timestamp = {2009-11-12T00:23:05.000+0100},
title = {Applications of genome-scale metabolic reconstructions},
url = {http://www.ncbi.nlm.nih.gov/pubmed/19888215?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1},
volume = 5,
year = 2009
}