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Features of Metabolic Changes in Hypoxic Lesions of the Central Nervous System in Newborns

. CENTRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCES, (2022)

Abstract

The neonatal period and the first year of a child's life are characterized by the most active period of brain maturation, and the action of such an aggressive factor as hypoxia on the developing brain of a child dictates the need for further study of this pathology. The most significant changes in the statistical indicators of mortality and morbidity were noted among premature babies. The high frequency of severe combined perinatal pathology in this category of children led to an increase in childhood disability, in the structure of which the leading positions (21.2%) belong to the pathology of the nervous system and sensory organs. Among the etiological factors that are most significant in the pathogenesis of perinatal cerebral injuries, the leading role belongs to hypoxia. Literary analysis showed the relevance of this problem, which served as the purpose of the distribution. The aim of the study was to establish the nature of clinical and instrumental, psychomotor and metabolic changes in hypoxic lesions of the central nervous system in newborns. We observed 60 newborns with a gestational age of 28 to 41 weeks with hypoxic lesions of the central nervous system of the early period.

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