%0 Journal Article %1 Whiting2011 %A Whiting, Penny F %A Rutjes, Anne W S %A Westwood, Marie E %A Mallett, Susan %A Deeks, Jonathan J %A Reitsma, Johannes B %A Leeflang, Mariska M G %A Sterne, Jonathan A C %A Bossuyt, Patrick M M %D 2011 %J Annals of internal medicine %K Bias(Epidemiology) Diagnosis Evidence-BasedMedicine Humans PatientSelection QualityControl Questionnaires ReferenceStandards ReviewLiteratureasTopic TimeFactors %N 8 %P 529-36 %R 10.7326/0003-4819-155-8-201110180-00009 %T QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. %U http://www.annals.org/content/155/8/529.abstract http://www.ncbi.nlm.nih.gov/pubmed/22007046 %V 155 %X In 2003, the QUADAS tool for systematic reviews of diagnostic accuracy studies was developed. Experience, anecdotal reports, and feedback suggested areas for improvement; therefore, QUADAS-2 was developed. This tool comprises 4 domains: patient selection, index test, reference standard, and flow and timing. Each domain is assessed in terms of risk of bias, and the first 3 domains are also assessed in terms of concerns regarding applicability. Signalling questions are included to help judge risk of bias. The QUADAS-2 tool is applied in 4 phases: summarize the review question, tailor the tool and produce review-specific guidance, construct a flow diagram for the primary study, and judge bias and applicability. This tool will allow for more transparent rating of bias and applicability of primary diagnostic accuracy studies.

@article{Whiting2011, abstract = {In 2003, the QUADAS tool for systematic reviews of diagnostic accuracy studies was developed. Experience, anecdotal reports, and feedback suggested areas for improvement; therefore, QUADAS-2 was developed. This tool comprises 4 domains: patient selection, index test, reference standard, and flow and timing. Each domain is assessed in terms of risk of bias, and the first 3 domains are also assessed in terms of concerns regarding applicability. Signalling questions are included to help judge risk of bias. The QUADAS-2 tool is applied in 4 phases: summarize the review question, tailor the tool and produce review-specific guidance, construct a flow diagram for the primary study, and judge bias and applicability. This tool will allow for more transparent rating of bias and applicability of primary diagnostic accuracy studies.}, added-at = {2023-02-03T11:44:35.000+0100}, author = {Whiting, Penny F and Rutjes, Anne W S and Westwood, Marie E and Mallett, Susan and Deeks, Jonathan J and Reitsma, Johannes B and Leeflang, Mariska M G and Sterne, Jonathan A C and Bossuyt, Patrick M M}, biburl = {https://www.bibsonomy.org/bibtex/274a3816d54f3a4ab8a3f8b04bd60a0cf/jepcastel}, doi = {10.7326/0003-4819-155-8-201110180-00009}, interhash = {86b31452bdc69b2491036994fa486dd2}, intrahash = {74a3816d54f3a4ab8a3f8b04bd60a0cf}, issn = {1539-3704}, journal = {Annals of internal medicine}, keywords = {Bias(Epidemiology) Diagnosis Evidence-BasedMedicine Humans PatientSelection QualityControl Questionnaires ReferenceStandards ReviewLiteratureasTopic TimeFactors}, month = {10}, note = {6383<m:linebreak></m:linebreak>Proves diagnòstiques; Critical appraisal; Checklist}, number = 8, pages = {529-36}, pmid = {22007046}, timestamp = {2023-02-03T11:44:35.000+0100}, title = {QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies.}, url = {http://www.annals.org/content/155/8/529.abstract http://www.ncbi.nlm.nih.gov/pubmed/22007046}, volume = 155, year = 2011 }