Article,

Staphylococcus aureus biofilms promote horizontal transfer of antibiotic resistance

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Antimicrob Agents Chemother, 57 (4): 1968-1970 (April 2013)
DOI: 10.1128/AAC.02008-12

Abstract

Growth as a biofilm facilitates the emergence of antibiotic resistance by mutation in Staphylococcus aureus. Here we demonstrate that biofilm growth of this species also dramatically increases horizontal transfer of plasmid-borne antibiotic resistance determinants by conjugation/mobilization and that standard laboratory practices to induce conjugation in staphylococci achieve optimal efficiency owing to the presence of a biofilm.

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