%0 Journal Article %1 WolfeBryant_99 %A Wolfe, J. %A Bryant, G. %D 1999 %J Cryobiology %K bibtex-import, cellular, citeulikeExport cryo, freezing, physics, solutes, tolerance %P 103--129 %T Freezing, drying and/or vitrification of membrane solute-water systems %U http://www.phys.unsw.edu.au/\~jw/Cryo99.pdf %V 39

@article{WolfeBryant_99, added-at = {2019-03-31T01:14:40.000+0100}, author = {Wolfe, J. and Bryant, G.}, biburl = {https://www.bibsonomy.org/bibtex/2656b7a17e7292fd9c2ca474333eec171/dianella}, citeulike-article-id = {1524128}, citeulike-linkout-0 = {http://www.phys.unsw.edu.au/\~{}jw/Cryo99.pdf}, comment = {(private-note)Vitrification of water if freeze fast enough. Viscosity increases with solute concentration, and the physical presence of solutes hinders nucleation of ice. Trehalose vs other sugars: it's less prone to crystalisation than eg. Sucrose, other sugars. A sucrose solution with small amounts of raffinose is also able to vitrify rather than crystallising. Trehalose has a higher glass transition temperature, though. Vitrification reduces the mechanical stresses on the macromolecules and membranes if it occurs near them. ---=note-separator=--- (private-note)The probability of nucleation (i.e., the formation of nuclei larger than the critical volume) is related to sample volume, the amount of undercooling (DT 5 Tf 2 T), and the viscosity of the liquid. As the liquid is cooled, the viscosity rises. If the liquid is cooled sufficiently quickly the viscosity may become so great that molecular rearrangements in the liquid become extremely slow or stop. Nucleation and crystal growth will be hindered, and the liquid will be in a stable nonequilibrium phase, which is amorphous (i.e., it has no long-range order, like a liquid), but which has mechanical properties like a solid. Such a phase is called a glass or vitrified solid, and the process by which it forms is called vitrification. A solution is said to be vitrified if its viscosity is greater than 10^14 Pa . s (15). For comparison the viscosity of water is \~{}1 mPa . s at 20°C.}, interhash = {934ca98aa4b33e6ff4776324e08da9e2}, intrahash = {656b7a17e7292fd9c2ca474333eec171}, journal = {Cryobiology}, keywords = {bibtex-import, cellular, citeulikeExport cryo, freezing, physics, solutes, tolerance}, pages = {103--129}, posted-at = {2007-07-31 07:40:19}, priority = {2}, timestamp = {2019-03-31T01:16:26.000+0100}, title = {{Freezing, drying and/or vitrification of membrane solute-water systems}}, url = {http://www.phys.unsw.edu.au/\~{}jw/Cryo99.pdf}, volume = 39, year = 1999 }