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1SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials.
A. Chan, J. Tetzlaff, P. Gøtzsche, D. Altman, H. Mann, J. Berlin, K. Dickersin, A. Hróbjartsson, K. Schulz, W. Parulekar and 3 other author(s). BMJ (Clinical research ed.), (January 2013)7139<m:linebreak></m:linebreak>JID: 8900488; OID: NLM: PMC3541470; epublish;<m:linebreak></m:linebreak>Protocol; RCT.
2 years ago by @jepcastel
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PatientSelection
ResearchDesign
QualityControl
ProfessionalRole
Ethics
RandomAllocation
ClinicalProtocols
SampleSize
ResearchPersonnel
MedicalAudit
DataCollection
Checklist
Medical
StatisticsasTopic
ClinicalTrialsasTopic:methods
DataCollection:methods
ResearchSupportasTopic
ClinicalTrialsDataMonitoringCommittees
Humans
ClinicalTrialsasTopic:statistics&numericald
TimeFactors
ClinicalProtocols:standards
PracticeGuidelinesasTopic
ClinicalTrialsasTopic:standards
ComputerSecurity
ClinicalTrialsasTopic
TreatmentOutcome
SocialResponsibility
PatientSelectionResearchDesignQualityControlProfessionalRoleEthicsRandomAllocationClinicalProtocolsSampleSizeResearchPersonnelMedicalAuditDataCollectionChecklistMedicalStatisticsasTopicClinicalTrialsasTopic:methodsDataCollection:methodsResearchSupportasTopicClinicalTrialsDataMonitoringCommitteesHumansClinicalTrialsasTopic:statistics&numericaldTimeFactorsClinicalProtocols:standardsPracticeGuidelinesasTopicClinicalTrialsasTopic:standardsComputerSecurityClinicalTrialsasTopicTreatmentOutcomeSocialResponsibility
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1Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative.
P. Bossuyt, J. Reitsma, D. Bruns, C. Gatsonis, P. Glasziou, L. Irwig, J. Lijmer, D. Moher, D. Rennie, and H. de Vet. BMJ (Clinical research ed.), 326 (7379): 41-4 (January 2003)7132<m:linebreak></m:linebreak>LR: 20120306; JID: 8900488; CIN: BMJ. 2003 Mar 15;326(7389):601. PMID: 12637417; CIN: BMJ. 2003 Jan 4;326(7379):3-4. PMID: 12511433; RF: 19; OID: NLM: PMC1124931; ppublish;<m:linebreak></m:linebreak>Publicació; Proves diagnòstiques.
2 years ago by @jepcastel
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Publishing
DiagnosticTechniquesandProcedures:standards
Algorithms
ResearchDesign
GuidelinesasTopic
ClinicalTrialsasTopic:standards
ResearchDesign:standards
Bias(Epidemiology)
DiagnosticTechniquesandProcedures
ClinicalTrialsasTopic
Publishing:standards
PublishingDiagnosticTechniquesandProcedures:standardsAlgorithmsResearchDesignGuidelinesasTopicClinicalTrialsasTopic:standardsResearchDesign:standardsBias(Epidemiology)DiagnosticTechniquesandProceduresClinicalTrialsasTopicPublishing:standards
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1No surgical innovation without evaluation: the IDEAL recommendations.
P. McCulloch, D. Altman, W. Campbell, D. Flum, P. Glasziou, J. Marshall, J. Nicholl, J. Aronson, J. Barkun, J. Blazeby and 38 other author(s). Lancet, 374 (9695): 1105-12 (September 2009)5332 JID: 2985213R; ppublish; Tipus d'estudis; Cirurgia.
2 years ago by @jepcastel
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BiomedicalResearch
EvaluationStudiesasTopic
ResearchSupportasTopic
RCT
ResearchDesign
Operative:standards
Humans
EditorialPolicies
SurgicalProcedures
Operative
ClinicalTrialsasTopic
TreatmentOutcome
BiomedicalResearchEvaluationStudiesasTopicResearchSupportasTopicRCTResearchDesignOperative:standardsHumansEditorialPoliciesSurgicalProceduresOperativeClinicalTrialsasTopicTreatmentOutcome
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1The use of systematic reviews when designing studies.
N. Cooper, D. Jones, and A. Sutton. Clinical trials (London, England), 2 (3): 260-4 (January 2005)4553<m:linebreak></m:linebreak>LR: 20071115; PUBM: Print; JID: 101197451; ppublish;<m:linebreak></m:linebreak>Disseny; Critical appraisal; Metaanàlisi.
2 years ago by @jepcastel
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Meta-AnalysisasTopic
ReviewLiteratureasTopic
ResearchDesign
Humans
DatabasesasTopic
Evidence-BasedMedicine
ClinicalTrialsasTopic
Meta-AnalysisasTopicReviewLiteratureasTopicResearchDesignHumansDatabasesasTopicEvidence-BasedMedicineClinicalTrialsasTopic
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1Statistics in medicine--reporting of subgroup analyses in clinical trials.
R. Wang, S. Lagakos, J. Ware, D. Hunter, and J. Drazen. The New England journal of medicine, 357 (21): 2189-94 (November 2007)4348 LR: 20080320; PUBM: Print; JID: 0255562; CIN: N Engl J Med. 2008 Mar 13;358(11):1199; author reply 1199-200. PMID: 18337613; CIN: N Engl J Med. 2008 Mar 13;358(11):1199; author reply 1199-200. PMID: 18340666; ppublish; Comparacions múltiples; Anàlisi de subgrups; RCT.
2 years ago by @jepcastel
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QualityControl
ClinicalTrialsasTopic:standards
StatisticsasTopic:methods
Statistical
ClinicalTrialsasTopic:statistics&numericald
ClinicalTrialsasTopic
DataInterpretation
StatisticsasTopic
QualityControlClinicalTrialsasTopic:standardsStatisticsasTopic:methodsStatisticalClinicalTrialsasTopic:statistics&numericaldClinicalTrialsasTopicDataInterpretationStatisticsasTopic
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1Missing data: discussion points from the PSI missing data expert group.
T. Burzykowski, J. Carpenter, C. Coens, D. Evans, L. France, M. Kenward, P. Lane, J. Matcham, D. Morgan, A. Phillips and 4 other author(s). Pharmaceutical statistics, 9 (4): 288-97 (2010)6078 CI: Copyright (c) 2009; JID: 101201192; ppublish; Dades censurades; Imputació múltiple.
2 years ago by @jepcastel
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DrugIndustry
PracticeGuidelinesasTopic:standards
PracticeGuidelinesasTopic
ResearchDesign
Humans
DrugIndustry:standards
ClinicalTrialsasTopic:standards
ResearchDesign:standards
ClinicalTrialsasTopic
DrugIndustryPracticeGuidelinesasTopic:standardsPracticeGuidelinesasTopicResearchDesignHumansDrugIndustry:standardsClinicalTrialsasTopic:standardsResearchDesign:standardsClinicalTrialsasTopic
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1Design of clinical trials.
D. Rollo, S. Machado, and M. Ceschin. Seminars in nuclear medicine, 40 (5): 332-7 (September 2010)5927<m:linebreak></m:linebreak>CI: Copyright 2010; JID: 1264464; 0 (Radiopharmaceuticals); ppublish;<m:linebreak></m:linebreak>Disseny; Tipus d'estudis; RCT.
2 years ago by @jepcastel
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Radiopharmaceuticals:economics
Radiopharmaceuticals:supply&distribution
ResearchDesign
Radiopharmaceuticals:adverseeffects
Humans
Radiopharmaceuticals:diagnosticuse
EarlyTerminationofClinicalTrials
EpidemiologicResearchDesign
Drug-RelatedSideEffectsandAdverseReactions
DiagnosticImaging
Disclosure
TimeFactors
NuclearMedicine:methods
NuclearMedicine
Bias(Epidemiology)
ClinicalTrialsasTopic
Radiopharmaceuticals
SocialResponsibility
DrugLabeling
ClinicalTrialsasTopic:methods
Radiopharmaceuticals:economicsRadiopharmaceuticals:supply&distributionResearchDesignRadiopharmaceuticals:adverseeffectsHumansRadiopharmaceuticals:diagnosticuseEarlyTerminationofClinicalTrialsEpidemiologicResearchDesignDrug-RelatedSideEffectsandAdverseReactionsDiagnosticImagingDisclosureTimeFactorsNuclearMedicine:methodsNuclearMedicineBias(Epidemiology)ClinicalTrialsasTopicRadiopharmaceuticalsSocialResponsibilityDrugLabelingClinicalTrialsasTopic:methods
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1The persistent exclusion of older patients from ongoing clinical trials regarding heart failure.
A. Cherubini, J. Oristrell, X. Pla, C. Ruggiero, R. Ferretti, G. Diestre, A. Clarfield, P. Crome, C. Hertogh, V. Lesauskaite and 6 other author(s). Archives of internal medicine, 171 (6): 550-6 (March 2011)6058.
2 years ago by @jepcastel
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Factual
PatientSelection
80andover
Humans
HeartFailure
LogisticModels
HeartFailure:drugtherapy
Aged
ClinicalTrialsasTopic
Databases
FactualPatientSelection80andoverHumansHeartFailureLogisticModelsHeartFailure:drugtherapyAgedClinicalTrialsasTopicDatabases
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1Canadian-led capacity-building in biostatistics and methodology in cardiovascular and diabetes trials: the CANNeCTIN Biostatistics and Methodological Innovation Working Group.
L. Thabane, G. Wells, R. Cook, R. Platt, J. Pogue, E. Pullenayegum, D. Matthews, T. McCready, P. Devereaux, J. Cairns and 1 other author(s). Trials, (January 2011)6243<m:linebreak></m:linebreak>GR: Canadian Institutes of Health Research/Canada; JID: 101263253; OID: NLM: PMC3049182; 2010/11/14 received; 2011/02/18 accepted; 2011/02/18 aheadofprint; epublish;<m:linebreak></m:linebreak>Recursos/Organització; Consulting.
2 years ago by @jepcastel
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Biostatistics
ProgramDevelopment
HealthServicesResearch:statistics&numericald
InformationDissemination
CardiovascularDiseases:therapy
DataInterpretation
Mentors
BiomedicalResearch
Canada
HealthServicesResearch:organization&administr
BiomedicalResearch:organization&administration
Statistical
DiabetesMellitus
Videoconferencing
CongressesasTopic
Humans
ClinicalTrialsasTopic:statistics&numericald
HealthServicesResearch
OrganizationalObjectives
ClinicalTrialsasTopic
DiabetesMellitus:therapy
TreatmentOutcome
BiomedicalResearch:statistics&numericaldata
CardiovascularDiseases
CapacityBuilding
BiostatisticsProgramDevelopmentHealthServicesResearch:statistics&numericaldInformationDisseminationCardiovascularDiseases:therapyDataInterpretationMentorsBiomedicalResearchCanadaHealthServicesResearch:organization&administrBiomedicalResearch:organization&administrationStatisticalDiabetesMellitusVideoconferencingCongressesasTopicHumansClinicalTrialsasTopic:statistics&numericaldHealthServicesResearchOrganizationalObjectivesClinicalTrialsasTopicDiabetesMellitus:therapyTreatmentOutcomeBiomedicalResearch:statistics&numericaldataCardiovascularDiseasesCapacityBuilding
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1Balancing the outcomes: reporting adverse events.
A. Keech, S. Wonders, D. Cook, and V. Gebski. The Medical journal of Australia, 181 (4): 215-8 (August 2004)5103<m:linebreak></m:linebreak>LR: 20071115; JID: 0400714; 2004/07/06 received; 2004/07/08 accepted; ppublish;.
2 years ago by @jepcastel
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AdverseDrugReactionReportingSystems:legislati
Publishing
RCT
PracticeGuidelinesasTopic
Humans
OutcomeAssessment(HealthCare)
ClinicalTrialsasTopic
AdverseDrugReactionReportingSystems
AdverseDrugReactionReportingSystems:legislatiPublishingRCTPracticeGuidelinesasTopicHumansOutcomeAssessment(HealthCare)ClinicalTrialsasTopicAdverseDrugReactionReportingSystems
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1Better reporting of interventions: template for intervention description and replication (TIDieR) checklist and guide.
T. Hoffmann, P. Glasziou, I. Boutron, R. Milne, R. Perera, D. Moher, D. Altman, V. Barbour, H. Macdonald, M. Johnston and 6 other author(s). BMJ (Clinical research ed.), (January 2014)Publicació; Checklist; Intervenció/placebo.
2 years ago by @jepcastel
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ReproducibilityofResults
ResearchReport
BiomedicalResearch
ProgramEvaluation
DelphiTechnique
ResearchDesign
Humans
ClinicalTrialsasTopic:standards
ResearchDesign:standards
Checklist
ClinicalTrialsasTopic
ResearchReport:standards
ReproducibilityofResultsResearchReportBiomedicalResearchProgramEvaluationDelphiTechniqueResearchDesignHumansClinicalTrialsasTopic:standardsResearchDesign:standardsChecklistClinicalTrialsasTopicResearchReport:standards
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1Expectations, validity, and reality in gene expression profiling.
K. Kim, S. Zakharkin, and D. Allison. Journal of clinical epidemiology, 63 (9): 950-9 (September 2010)7117<m:linebreak></m:linebreak>LR: 20110913; GR: P01 AG025532-02/AG/NIA NIH HHS/United States; GR: P01 AG025532-03/AG/NIA NIH HHS/United States; GR: P01AG025532/AG/NIA NIH HHS/United States; GR: P30 DK056336-05/DK/NIDDK NIH HHS/United States; GR: P30DK056336/DK/NIDDK NIH HHS/United States; JID: 8801383; 0 (Biological Markers); NIHMS199602; OID: NLM: NIHMS199602; OID: NLM: PMC2910173; 2009/06/11 received; 2010/02/09 revised; 2010/02/11 accepted; 2010/06/25 aheadofprint; ppublish;<m:linebreak></m:linebreak>Epidemiologia genètica.
2 years ago by @jepcastel
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Neoplasms:diagnosis
Humans
GeneExpressionProfiling:instrumentation
Neoplasms:genetics
Transcription
Genetic
Neoplasms
BiologicalMarkers
GeneExpressionProfiling
InformationStorageandRetrieval:methods
ReproducibilityofResults
MicroarrayAnalysis:methods
MicroarrayAnalysis
InformationStorageandRetrieval
GeneExpressionProfiling:methods
Genetic:genetics
ClinicalTrialsasTopic
Databases
Neoplasms:diagnosisHumansGeneExpressionProfiling:instrumentationNeoplasms:geneticsTranscriptionGeneticNeoplasmsBiologicalMarkersGeneExpressionProfilingInformationStorageandRetrieval:methodsReproducibilityofResultsMicroarrayAnalysis:methodsMicroarrayAnalysisInformationStorageandRetrievalGeneExpressionProfiling:methodsGenetic:geneticsClinicalTrialsasTopicDatabases
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2The ADVANTAGE seeding trial: a review of internal documents.
K. Hill, J. Ross, D. Egilman, and H. Krumholz. Annals of internal medicine, 149 (4): 251-8 (August 2008)4606<m:linebreak></m:linebreak>LR: 20081203; JID: 0372351; 0 (Cyclooxygenase 2 Inhibitors); 0 (Lactones); 0 (Sulfones); 0 (rofecoxib); CIN: Ann Intern Med. 2008 Aug 19;149(4):279-80. PMID: 18711161; CIN: Ann Intern Med. 2008 Nov 18;149(10):773; author reply 773-4. PMID: 19017606; CIN: Ann Intern Med. 2008 Nov 18;149(10):774. PMID: 19017608; RF: 32; ppublish;<m:linebreak></m:linebreak>Tipus d'estudis; Seeding trials.
2 years ago by @jepcastel
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EthicsCommittees
Cyclooxygenase2Inhibitors
GastrointestinalDiseases
Sulfones:therapeuticuse
ClinicalTrialsasTopic:ethics
GastrointestinalDiseases:chemicallyinduced
Humans
Deception
Cyclooxygenase2Inhibitors:therapeuticuse
Lactones:therapeuticuse
Research
Marketing:ethics
Marketing
Disclosure
Cyclooxygenase2Inhibitors:adverseeffects
Lactones
DrugIndustry:ethics
DrugIndustry
Sulfones:adverseeffects
Lactones:adverseeffects
ClinicalTrialsasTopic:standards
ConflictofInterest
ClinicalTrialsasTopic
Sulfones
EthicsCommitteesCyclooxygenase2InhibitorsGastrointestinalDiseasesSulfones:therapeuticuseClinicalTrialsasTopic:ethicsGastrointestinalDiseases:chemicallyinducedHumansDeceptionCyclooxygenase2Inhibitors:therapeuticuseLactones:therapeuticuseResearchMarketing:ethicsMarketingDisclosureCyclooxygenase2Inhibitors:adverseeffectsLactonesDrugIndustry:ethicsDrugIndustrySulfones:adverseeffectsLactones:adverseeffectsClinicalTrialsasTopic:standardsConflictofInterestClinicalTrialsasTopicSulfones
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1A framework for risk-benefit evaluations in biomedical research.
A. Rid, and D. Wendler. Kennedy Institute of Ethics journal, 21 (2): 141-79 (June 2011)6275<m:linebreak></m:linebreak>JID: 9109135; ppublish; Consultar-lo a la web (40 pàgines!)<m:linebreak></m:linebreak>Relació benefici/risc.
2 years ago by @jepcastel
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BiomedicalResearch:standards
RiskAssessment
ClinicalTrialsasTopic:ethics
Humans
Research:standards
Research
InformedConsent
Ethics
BiomedicalResearch
RiskAssessment:standards
BiomedicalResearch:organization&administration
InformedConsent:standards
ClinicalTrialsasTopic:standards
InformedConsent:ethics
SocialValues
Research:organization&administration
RiskAssessment:methods
ClinicalTrialsasTopic
BiomedicalResearch:ethics
RiskAssessment:trends
BiomedicalResearch:standardsRiskAssessmentClinicalTrialsasTopic:ethicsHumansResearch:standardsResearchInformedConsentEthicsBiomedicalResearchRiskAssessment:standardsBiomedicalResearch:organization&administrationInformedConsent:standardsClinicalTrialsasTopic:standardsInformedConsent:ethicsSocialValuesResearch:organization&administrationRiskAssessment:methodsClinicalTrialsasTopicBiomedicalResearch:ethicsRiskAssessment:trends
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1Breaking up is hard to do: the heartbreak of dichotomizing continuous data.
D. Streiner. Canadian journal of psychiatry. Revue canadienne de psychiatrie, 47 (3): 262-6 (April 2002)5206<m:linebreak></m:linebreak>LR: 20071115; JID: 7904187; CIN: Can J Psychiatry. 2002 Nov;47(9):886. PMID: 12500760; CIN: Can J Psychiatry. 2003 Jul;48(6):429-30; author reply 430. PMID: 12894624; ppublish;<m:linebreak></m:linebreak>Anàlisi de dades; Categorització.
2 years ago by @jepcastel
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Humans
PsychiatricStatusRatingScales:statistics&num
Psychometrics
Statistical
ClinicalTrialsasTopic:statistics&numericald
Bias(Epidemiology)
OutcomeAssessment(HealthCare)
ClinicalTrialsasTopic
DataInterpretation
PsychiatricStatusRatingScales
OutcomeAssessment(HealthCare):statistics&num
HumansPsychiatricStatusRatingScales:statistics&numPsychometricsStatisticalClinicalTrialsasTopic:statistics&numericaldBias(Epidemiology)OutcomeAssessment(HealthCare)ClinicalTrialsasTopicDataInterpretationPsychiatricStatusRatingScalesOutcomeAssessment(HealthCare):statistics&num
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1Recommended methods for determining responsiveness and minimally important differences for patient-reported outcomes.
D. Revicki, R. Hays, D. Cella, and J. Sloan. Journal of clinical epidemiology, 61 (2): 102-9 (February 2008)4488<m:linebreak></m:linebreak>PUBM: Print-Electronic; GR: AG-02-004/AG/United States NIA; GR: AG20679-01/AG/United States NIA; GR: P20-MD00148-01/MD/United States NCMHD; JID: 8801383; RF: 52; 2006/10/06 received; 2007/03/27 revised; 2007/03/31 accepted; 2007/08/03 aheadofprint; ppublish;<m:linebreak></m:linebreak>MDCI.
2 years ago by @jepcastel
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QualityofLife
ResearchDesign
Humans
OutcomeAssessment(HealthCare):methods
PatientSatisfaction
Statistical
HealthStatusIndicators
OutcomeAssessment(HealthCare)
ClinicalTrialsasTopic
DataInterpretation
TreatmentOutcome
ClinicalTrialsasTopic:methods
QualityofLifeResearchDesignHumansOutcomeAssessment(HealthCare):methodsPatientSatisfactionStatisticalHealthStatusIndicatorsOutcomeAssessment(HealthCare)ClinicalTrialsasTopicDataInterpretationTreatmentOutcomeClinicalTrialsasTopic:methods
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1Clinician-trialist rounds: 7. Mentoring: why every clinician-trialist needs to get mentored.
S. Straus, and D. Sackett. Clinical trials (London, England), 8 (6): 765-7 (December 2011)6627<m:linebreak></m:linebreak>JID: 101197451; ppublish;<m:linebreak></m:linebreak>Disseny; RCT; Recerca clínica.
2 years ago by @jepcastel
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MedicalStaff
BiomedicalResearch
AcademicMedicalCenters
Humans
Hospital
ClinicalTrialsasTopic
Mentors
MedicalStaffBiomedicalResearchAcademicMedicalCentersHumansHospitalClinicalTrialsasTopicMentors
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1Dangers of non-specific composite outcome measures in clinical trials.
D. Prieto-Merino, L. Smeeth, T. van Staa, and I. Roberts. BMJ (Clinical research ed.), (January 2013)7569<m:linebreak></m:linebreak>Comparacions múltiples; Composite endpoints.
2 years ago by @jepcastel
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ResearchDesign
Humans
OutcomeAssessment(HealthCare):methods
OutcomeAssessment(HealthCare)
ClinicalTrialsasTopic
StatisticsasTopic
TreatmentOutcome
Causality
ClinicalTrialsasTopic:methods
ResearchDesignHumansOutcomeAssessment(HealthCare):methodsOutcomeAssessment(HealthCare)ClinicalTrialsasTopicStatisticsasTopicTreatmentOutcomeCausalityClinicalTrialsasTopic:methods
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publications (hide)18
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1SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials.

1Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative.

1No surgical innovation without evaluation: the IDEAL recommendations.

1The use of systematic reviews when designing studies.

1Statistics in medicine--reporting of subgroup analyses in clinical trials.

1Missing data: discussion points from the PSI missing data expert group.

1Design of clinical trials.

1The persistent exclusion of older patients from ongoing clinical trials regarding heart failure.

1Canadian-led capacity-building in biostatistics and methodology in cardiovascular and diabetes trials: the CANNeCTIN Biostatistics and Methodological Innovation Working Group.

1Balancing the outcomes: reporting adverse events.

1Better reporting of interventions: template for intervention description and replication (TIDieR) checklist and guide.

1Expectations, validity, and reality in gene expression profiling.

2The ADVANTAGE seeding trial: a review of internal documents.

1A framework for risk-benefit evaluations in biomedical research.

1Breaking up is hard to do: the heartbreak of dichotomizing continuous data.

1Recommended methods for determining responsiveness and minimally important differences for patient-reported outcomes.

1Clinician-trialist rounds: 7. Mentoring: why every clinician-trialist needs to get mentored.

1Dangers of non-specific composite outcome measures in clinical trials.

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publications (hide)18 displayallpublications onlypublications per page5102050100 sort byadded attitleauthorpublication dateentry typehelp for advanced sorting... RSSBibTeXRDFmore...

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