Hoffmann > Humans | BibSonomy

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1Better reporting of interventions: template for intervention description and replication (TIDieR) checklist and guide.
T. Hoffmann, P. Glasziou, I. Boutron, R. Milne, R. Perera, D. Moher, D. Altman, V. Barbour, H. Macdonald, M. Johnston and 6 other author(s). BMJ (Clinical research ed.), (January 2014)Publicació; Checklist; Intervenció/placebo.
2 years ago by @jepcastel
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ReproducibilityofResults
ResearchReport
BiomedicalResearch
ProgramEvaluation
DelphiTechnique
ResearchDesign
Humans
ClinicalTrialsasTopic:standards
ResearchDesign:standards
Checklist
ClinicalTrialsasTopic
ResearchReport:standards
ReproducibilityofResultsResearchReportBiomedicalResearchProgramEvaluationDelphiTechniqueResearchDesignHumansClinicalTrialsasTopic:standardsResearchDesign:standardsChecklistClinicalTrialsasTopicResearchReport:standards
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1A functional polymorphism in the NAD(P)H oxidase subunit CYBA is related to gene expression, enzyme activity, and outcome in non-Hodgkin lymphoma
M. Hoffmann, M. Schirmer, M. Tzvetkov, M. Kreuz, M. Ziepert, L. Wojnowski, D. Kube, M. Pfreundschuh, L. Trümper, M. Loeffler and 1 other author(s). Cancer research, 70 (6): 2328–2338 (2010)
10 years ago by @drtester
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Middle_Aged
RNA,_Messenger/biosynthesis/genetics
Treatment_Outcome
Doxorubicin/administration_&_dosage
Humans
Prednisolone/administration_&_dosage
Male
Gene_Expression
Polymorphism,_Single_Nucleotide
Vincristine/administration_&_dosage
Protein_Subunits
Young_Adult
Adolescent
Cyclophosphamide/administration_&_dosage
Antineoplastic_Combined_Chemotherapy_Protocols/administration_&_dosage/therapeutic_use
NADPH_Oxidase/biosynthesis/genetics/metabolism
Adult
Lymphoma,_Non-Hodgkin/drug_therapy/enzymology/genetics
Etoposide/administration_&_dosage
Female
Middle_AgedRNA,_Messenger/biosynthesis/geneticsTreatment_OutcomeDoxorubicin/administration_&_dosageHumansPrednisolone/administration_&_dosageMaleGene_ExpressionPolymorphism,_Single_NucleotideVincristine/administration_&_dosageProtein_SubunitsYoung_AdultAdolescentCyclophosphamide/administration_&_dosageAntineoplastic_Combined_Chemotherapy_Protocols/administration_&_dosage/therapeutic_useNADPH_Oxidase/biosynthesis/genetics/metabolismAdultLymphoma,_Non-Hodgkin/drug_therapy/enzymology/geneticsEtoposide/administration_&_dosageFemale
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1Imaging genetics of FOXP2 in dyslexia
A. Wilcke, C. Ligges, J. Burkhardt, M. Alexander, C. Wolf, E. Quente, P. Ahnert, P. Hoffmann, A. Becker, B. Müller-Myhsok and 3 other author(s). European journal of human genetics : EJHG, 20 (2): 224–229 (2012)
10 years ago by @drtester
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Middle_Aged
Magnetic_Resonance_Imaging
Hippocampus/metabolism/pathology
Humans
Child,_Preschool
Male
Infant
Polymorphism,_Single_Nucleotide
Young_Adult
Gene_Expression_Profiling
Infant,_Newborn
Adolescent
Alleles
Gene_Expression_Regulation
Adult
Forkhead_Transcription_Factors/genetics
Child
Dyslexia/diagnosis/genetics
Female
Middle_AgedMagnetic_Resonance_ImagingHippocampus/metabolism/pathologyHumansChild,_PreschoolMaleInfantPolymorphism,_Single_NucleotideYoung_AdultGene_Expression_ProfilingInfant,_NewbornAdolescentAllelesGene_Expression_RegulationAdultForkhead_Transcription_Factors/geneticsChildDyslexia/diagnosis/geneticsFemale
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1Microarray-based genotyping and clinical outcomes of Staphylococcus aureus bloodstream infection: an exploratory study
S. Rieg, D. Jonas, A. Kaasch, C. Porzelius, G. Peyerl-Hoffmann, C. Theilacker, M. Küpper, C. Schneider, H. Seifert, and W. Kern. PloS one, 8 (8): e71259 (2013)
10 years ago by @drtester
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Prognosis
Genotyping_Techniques
Tropism/genetics
Oligonucleotide_Array_Sequence_Analysis
Humans
Bacteremia/diagnosis/microbiology
Male
Staphylococcus_aureus/genetics/growth_&_development/physiology
Prospective_Studies
Blood_Vessels/microbiology
Staphylococcal_Infections/diagnosis/microbiology
Cohort_Studies
Joint_Diseases/microbiology
Bone_Diseases,_Infectious/diagnosis/microbiology
Aged
Endocarditis,_Bacterial/diagnosis/microbiology
Female
PrognosisGenotyping_TechniquesTropism/geneticsOligonucleotide_Array_Sequence_AnalysisHumansBacteremia/diagnosis/microbiologyMaleStaphylococcus_aureus/genetics/growth_&_development/physiologyProspective_StudiesBlood_Vessels/microbiologyStaphylococcal_Infections/diagnosis/microbiologyCohort_StudiesJoint_Diseases/microbiologyBone_Diseases,_Infectious/diagnosis/microbiologyAgedEndocarditis,_Bacterial/diagnosis/microbiologyFemale
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4Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing
J. Richter, M. Schlesner, S. Hoffmann, M. Kreuz, E. Leich, B. Burkhardt, M. Rosolowski, O. Ammerpohl, R. Wagener, S. Bernhart and 45 other author(s). Nature genetics, 44 (12): 1316–1320 (2012)
10 years ago by @drtester
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Transcriptome/genetics
Molecular_Sequence_Data
Humans
Genes,_myc/genetics
Male
Burkitt_Lymphoma/genetics
Somatic_Hypermutation,_Immunoglobulin
Translocation,_Genetic/genetics
Chromosome_Mapping
Cohort_Studies
Genes,_Immunoglobulin
Base_Sequence
Inhibitor_of_Differentiation_Proteins/genetics
Mutation
Genome,_Human
Female
Chromosomes,_Human,_Pair_14/genetics
Neoplasm_Proteins/genetics
Chromosomes,_Human,_Pair_8/genetics
Sequence_Analysis,_DNA
Transcriptome/geneticsMolecular_Sequence_DataHumansGenes,_myc/geneticsMaleBurkitt_Lymphoma/geneticsSomatic_Hypermutation,_ImmunoglobulinTranslocation,_Genetic/geneticsChromosome_MappingCohort_StudiesGenes,_ImmunoglobulinBase_SequenceInhibitor_of_Differentiation_Proteins/geneticsMutationGenome,_HumanFemaleChromosomes,_Human,_Pair_14/geneticsNeoplasm_Proteins/geneticsChromosomes,_Human,_Pair_8/geneticsSequence_Analysis,_DNA
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1Alu elements in ANRIL non-coding RNA at chromosome 9p21 modulate atherogenic cell functions through trans-regulation of gene networks
L. Holdt, S. Hoffmann, K. Sass, D. Langenberger, M. Scholz, K. Krohn, K. Finstermeier, A. Stahringer, W. Wilfert, F. Beutner and 8 other author(s). PLoS genetics, 9 (7): e1003588 (2013)
10 years ago by @drtester
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RNA,_Long_Noncoding/genetics
Chromosomes,_Human,_Pair_9/genetics
Humans
Polymorphism,_Single_Nucleotide
Apoptosis/genetics
Cell_Proliferation
Genome-Wide_Association_Study
Genetic_Predisposition_to_Disease
Atherosclerosis/genetics/pathology
Alu_Elements/genetics
HEK293_Cells
Gene_Expression_Regulation
Gene_Regulatory_Networks
Cell_Adhesion/genetics
Epigenesis,_Genetic
Polycomb-Group_Proteins
Coronary_Artery_Disease/genetics/pathology
RNA,_Long_Noncoding/geneticsChromosomes,_Human,_Pair_9/geneticsHumansPolymorphism,_Single_NucleotideApoptosis/geneticsCell_ProliferationGenome-Wide_Association_StudyGenetic_Predisposition_to_DiseaseAtherosclerosis/genetics/pathologyAlu_Elements/geneticsHEK293_CellsGene_Expression_RegulationGene_Regulatory_NetworksCell_Adhesion/geneticsEpigenesis,_GeneticPolycomb-Group_ProteinsCoronary_Artery_Disease/genetics/pathology
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1Novel mutants of the human beta1-adrenergic receptor reveal amino acids relevant for receptor activation
B. Behr, C. Hoffmann, G. Ottolina, and K. Klotz. J Biol Chem, 281 (26): 18120-5 (June 2006)Behr, Bjorn Hoffmann, Carsten Ottolina, Gianluca Klotz, Karl-Norbert Research Support, Non-U.S. Gov't United States The Journal of biological chemistry J Biol Chem. 2006 Jun 30;281(26):18120-5. Epub 2006 Apr 28..
14 years ago by @pharmawuerz
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Structure,
Cricetinae
Secondary
Tertiary
Radioligand
Data
Sequence
Protein
Animals
Receptor
Mutagenesis
Ligands
Terbutaline/metabolism/pharmacology
Acid
Acid/genetics
Humans
Lysine/genetics
CHO
Isoleucine/genetics
Isoxazoles/metabolism/pharmacology
Adrenergic
beta-1/chemistry/*genetics/*metabolism
Assay
Molecular
Valine/genetics
Amino
Aspartic
beta-Agonists/metabolism/pharmacology
Cell
Structure,CricetinaeSecondaryTertiaryRadioligandDataSequenceProteinAnimalsReceptorMutagenesisLigandsTerbutaline/metabolism/pharmacologyAcidAcid/geneticsHumansLysine/geneticsCHOIsoleucine/geneticsIsoxazoles/metabolism/pharmacologyAdrenergicbeta-1/chemistry/*genetics/*metabolismAssayMolecularValine/geneticsAminoAsparticbeta-Agonists/metabolism/pharmacologyCell
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1Conformational changes in G-protein-coupled receptors-the quest for functionally selective conformations is open
C. Hoffmann, A. Zurn, M. Bunemann, and M. Lohse. Br J Pharmacol, (March 2008)Hoffmann, C Zurn, A Bunemann, M Lohse, M J Research Support, Non-U.S. Gov't Review England British journal of pharmacology Br J Pharmacol. 2008 Mar;153 Suppl 1:S358-66. Epub 2007 Dec 3..
14 years ago by @pharmawuerz
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beta-2/chemistry/drug
M3/chemistry/drug
Humans
Rhodopsin/chemistry/drug
Fluorescence
Muscarinic
Drug/chemistry/drug
Adrenergic
G-Protein-Coupled/*chemistry/drug
Protein
effects
Agents/pharmacology
Animals
Receptor
Chelating
Transfer
Resonance
Energy
Conformation
beta-2/chemistry/drugM3/chemistry/drugHumansRhodopsin/chemistry/drugFluorescenceMuscarinicDrug/chemistry/drugAdrenergicG-Protein-Coupled/*chemistry/drugProteineffectsAgents/pharmacologyAnimalsReceptorChelatingTransferResonanceEnergyConformation
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1Monitoring receptor signaling by intramolecular FRET
M. Lohse, M. Bunemann, C. Hoffmann, J. Vilardaga, and V. Nikolaev. Curr Opin Pharmacol, 7 (5): 547-53 (October 2007)Lohse, Martin J Bunemann, Moritz Hoffmann, Carsten Vilardaga, Jean-Pierre Nikolaev, Viacheslav O Review England Current opinion in pharmacology Curr Opin Pharmacol. 2007 Oct;7(5):547-53. Epub 2007 Oct 4..
14 years ago by @pharmawuerz
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Humans
Arrestins/metabolism
*Signal
Animals
Receptor
*Fluorescence
Cyclic
Transfer
Resonance
Transduction
Energy
G-Protein-Coupled/metabolism
AMP/metabolism
HumansArrestins/metabolism*SignalAnimalsReceptor*FluorescenceCyclicTransferResonanceTransductionEnergyG-Protein-Coupled/metabolismAMP/metabolism
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1Paradoxical block of parathormone secretion is mediated by increased activity of G alpha subunits
U. Quitterer, M. Hoffmann, M. Freichel, and M. Lohse. J Biol Chem, 276 (9): 6763-9 (March 2001)Quitterer, U Hoffmann, M Freichel, M Lohse, M J Research Support, Non-U.S. Gov't United States The Journal of biological chemistry J Biol Chem. 2001 Mar 2;276(9):6763-9. Epub 2000 Dec 1..
14 years ago by @pharmawuerz
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Calcium-Sensing
Deficiency/*metabolism
Inositol
Magnesium/metabolism
Rats
Protein
Proteins/*physiology
Toxin
Animals
Receptor
Cyclic
Surface/*physiology
Phosphates/biosynthesis
Humans
Virulence
Hormone/*secretion
Bordetella/pharmacology
Factors,
Magnesium
AMP/biosynthesis
Subunits
GTP-Binding
Parathyroid
Cell
Pertussis
Calcium-SensingDeficiency/*metabolismInositolMagnesium/metabolismRatsProteinProteins/*physiologyToxinAnimalsReceptorCyclicSurface/*physiologyPhosphates/biosynthesisHumansVirulenceHormone/*secretionBordetella/pharmacologyFactors,MagnesiumAMP/biosynthesisSubunitsGTP-BindingParathyroidCellPertussis
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1Site-specific, orthogonal labeling of proteins in intact cells with two small biarsenical fluorophores
A. Zurn, C. Klenk, U. Zabel, S. Reiner, M. Lohse, and C. Hoffmann. Bioconjug Chem, 21 (5): 853-9 (May 2010)Zurn, Alexander Klenk, Christoph Zabel, Ulrike Reiner, Susanne Lohse, Martin J Hoffmann, Carsten Research Support, Non-U.S. Gov't United States Bioconjugate chemistry Bioconjug Chem. 2010 May 19;21(5):853-9..
14 years ago by @pharmawuerz
show all tags
Binding
Transfer/*methods
Acid
Hormone,
Humans
Data
Sequence
Fluorescence
Arrestins/analysis/chemistry/metabolism
Protein
Type
1/analysis/chemistry/metabolism
Receptor
Molecular
Proteins/*analysis/chemistry/*metabolism
Line
Fluorescent
Resonance
Amino
Energy
Parathyroid
Dyes/*chemistry/metabolism
Cell
BindingTransfer/*methodsAcidHormone,HumansDataSequenceFluorescenceArrestins/analysis/chemistry/metabolismProteinType1/analysis/chemistry/metabolismReceptorMolecularProteins/*analysis/chemistry/*metabolismLineFluorescentResonanceAminoEnergyParathyroidDyes/*chemistry/metabolismCell
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1Agonist-selective, receptor-specific interaction of human P2Y receptors with beta-arrestin-1 and -2
C. Hoffmann, N. Ziegler, S. Reiner, C. Krasel, and M. Lohse. J Biol Chem, 283 (45): 30933-41 (November 2008)Hoffmann, Carsten Ziegler, Nicole Reiner, Susanne Krasel, Cornelius Lohse, Martin J Research Support, Non-U.S. Gov't United States The Journal of biological chemistry J Biol Chem. 2008 Nov 7;283(45):30933-41. Epub 2008 Aug 14..
14 years ago by @pharmawuerz
show all tags
aethiops
Humans
effects/physiology
Transport/drug
COS
Purinergic
P2/*agonists/genetics/*metabolism
Transduction/drug
Catalytic
Diphosphate/*pharmacology
Protein
Arrestins/genetics/*metabolism
Animals
Receptor
Uridine
effects/*physiology
Triphosphate/*pharmacology
Cercopithecus
Adenosine
Signal
Cell
Domain/physiology
aethiopsHumanseffects/physiologyTransport/drugCOSPurinergicP2/*agonists/genetics/*metabolismTransduction/drugCatalyticDiphosphate/*pharmacologyProteinArrestins/genetics/*metabolismAnimalsReceptorUridineeffects/*physiologyTriphosphate/*pharmacologyCercopithecusAdenosineSignalCellDomain/physiology
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1A FlAsH-based FRET approach to determine G protein-coupled receptor activation in living cells
C. Hoffmann, G. Gaietta, M. Bunemann, S. Adams, S. Oberdorff-Maass, B. Behr, J. Vilardaga, R. Tsien, M. Ellisman, and M. Lohse. Nat Methods, 2 (3): 171-6 (March 2005)Hoffmann, Carsten Gaietta, Guido Bunemann, Moritz Adams, Stephen R Oberdorff-Maass, Silke Behr, Bjorn Vilardaga, Jean-Pierre Tsien, Roger Y Ellisman, Mark H Lohse, Martin J P41RR004050/RR/NCRR NIH HHS/United States Comparative Study Evaluation Studies Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. United States Nature methods Nat Methods. 2005 Mar;2(3):171-6. Epub 2005 Feb 17..
14 years ago by @pharmawuerz
show all tags
Transfer/*methods
Interaction
COS
Kidney/*metabolism
Protein
Animals
Receptor
Hela
Resonance
Adenosine
Green
Dyes
aethiops
Humans
Mapping/*methods
Fluorescence
Proteins/metabolism
A2A
Proteins
G-Protein-Coupled/*metabolism
Fluorescent
GTP-Binding
Cultured
Energy
Cercopithecus
Cell
Transfer/*methodsInteractionCOSKidney/*metabolismProteinAnimalsReceptorHelaResonanceAdenosineGreenDyesaethiopsHumansMapping/*methodsFluorescenceProteins/metabolismA2AProteinsG-Protein-Coupled/*metabolismFluorescentGTP-BindingCulturedEnergyCercopithecusCell
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1Gs activation is time-limiting in initiating receptor-mediated signaling
P. Hein, F. Rochais, C. Hoffmann, S. Dorsch, V. Nikolaev, S. Engelhardt, C. Berlot, M. Lohse, and M. Bunemann. J Biol Chem, 281 (44): 33345-51 (November 2006)Hein, Peter Rochais, Francesca Hoffmann, Carsten Dorsch, Sandra Nikolaev, Viacheslav O Engelhardt, Stefan Berlot, Catherine H Lohse, Martin J Bunemann, Moritz Research Support, Non-U.S. Gov't United States The Journal of biological chemistry J Biol Chem. 2006 Nov 3;281(44):33345-51. Epub 2006 Sep 8..
14 years ago by @pharmawuerz
show all tags
Factors
Binding
Gs/genetics/*metabolism
beta-1/genetics/*metabolism
Humans
Activation
A2A/genetics/*metabolism
Time
Adrenergic
Protein
*Signal
Receptor
Cyclic
alpha
Line
Kinetics
GTP-Binding
Transduction
Enzyme
Adenosine
AMP/metabolism
Cell
Subunits,
FactorsBindingGs/genetics/*metabolismbeta-1/genetics/*metabolismHumansActivationA2A/genetics/*metabolismTimeAdrenergicProtein*SignalReceptorCyclicalphaLineKineticsGTP-BindingTransductionEnzymeAdenosineAMP/metabolismCellSubunits,
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1A fluorescence resonance energy transfer-based M2 muscarinic receptor sensor reveals rapid kinetics of allosteric modulation
M. Maier-Peuschel, N. Frolich, C. Dees, L. Hommers, C. Hoffmann, V. Nikolaev, and M. Lohse. J Biol Chem, 285 (12): 8793-800 (March 2010)Maier-Peuschel, Monika Frolich, Nadine Dees, Christian Hommers, Leif G Hoffmann, Carsten Nikolaev, Viacheslav O Lohse, Martin J Research Support, Non-U.S. Gov't United States The Journal of biological chemistry J Biol Chem. 2010 Mar 19;285(12):8793-800. Epub 2010 Jan 18..
14 years ago by @pharmawuerz
show all tags
Transfer/*methods
Confocal/methods
Structure,
Cricetinae
Tertiary
Concentration
M2/*chemistry
Acetylcholine/chemistry
Protein
Animals
Proteins/chemistry
Receptor
Inhibitory
Carbachol/chemistry
Microscopy,
Resonance
Gallamine
Ligands
Green
Site
Cricetulus
Triethiodide/chemistry
Humans
CHO
Fluorescence
Muscarinic
Allosteric
Fluorescent
50
Energy
Phthalimides/chemistry
Cell
Transfer/*methodsConfocal/methodsStructure,CricetinaeTertiaryConcentrationM2/*chemistryAcetylcholine/chemistryProteinAnimalsProteins/chemistryReceptorInhibitoryCarbachol/chemistryMicroscopy,ResonanceGallamineLigandsGreenSiteCricetulusTriethiodide/chemistryHumansCHOFluorescenceMuscarinicAllostericFluorescent50EnergyPhthalimides/chemistryCell
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1beta-Arrestin-2 interaction and internalization of the human P2Y1 receptor are dependent on C-terminal phosphorylation sites
S. Reiner, N. Ziegler, C. Leon, K. Lorenz, K. von Hayn, C. Gachet, M. Lohse, and C. Hoffmann. Mol Pharmacol, 76 (6): 1162-71 (December 2009)Reiner, Susanne Ziegler, Nicole Leon, Catherine Lorenz, Kristina von Hayn, Kathrin Gachet, Christian Lohse, Martin J Hoffmann, Carsten Research Support, Non-U.S. Gov't United States Molecular pharmacology Mol Pharmacol. 2009 Dec;76(6):1162-71. Epub 2009 Sep 9..
14 years ago by @pharmawuerz
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Arrestins/metabolism/*physiology
Catalytic
Calcium/analysis
Protein
effects
Enzyme-Linked
Receptor
Kinase
P2/metabolism/*physiology
Line
C/physiology
Microscopy,
Transfer
Resonance
Binding/drug
Phosphorylation
Humans
Purinergic
Confocal
Fluorescence
Calcium-Calmodulin-Dependent
Kidney/chemistry/enzymology/metabolism
Assay
Kinases/physiology
Immunosorbent
Energy
Cell
Domain/drug
Arrestins/metabolism/*physiologyCatalyticCalcium/analysisProteineffectsEnzyme-LinkedReceptorKinaseP2/metabolism/*physiologyLineC/physiologyMicroscopy,TransferResonanceBinding/drugPhosphorylationHumansPurinergicConfocalFluorescenceCalcium-Calmodulin-DependentKidney/chemistry/enzymology/metabolismAssayKinases/physiologyImmunosorbentEnergyCellDomain/drug
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1Synthesis of enantiopure Delta2-isoxazoline derivatives and evaluation of their affinity and efficacy profiles at human beta-adrenergic receptor subtypes
C. Dallanoce, G. Meroni, M. Amici, C. Hoffmann, K. Klotz, and C. Micheli. Bioorg Med Chem, 14 (13): 4393-401 (July 2006)Dallanoce, Clelia Meroni, Giuseppe De Amici, Marco Hoffmann, Carsten Klotz, Karl-Norbert De Micheli, Carlo Research Support, Non-U.S. Gov't England Bioorganic & medicinal chemistry Bioorg Med Chem. 2006 Jul 1;14(13):4393-401. Epub 2006 Mar 10..
14 years ago by @pharmawuerz
show all tags
beta-Antagonists/chemical
Cricetinae
Cricetulus
Humans
Isoxazoles/chemical
Stereoisomerism
CHO
Adrenergic
effects
Animals
Receptor
synthesis/*chemistry/*pharmacology
Cell
beta/*drug
beta-Antagonists/chemicalCricetinaeCricetulusHumansIsoxazoles/chemicalStereoisomerismCHOAdrenergiceffectsAnimalsReceptorsynthesis/*chemistry/*pharmacologyCellbeta/*drug
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1Kinetic analysis of G protein-coupled receptor signaling using fluorescence resonance energy transfer in living cells
M. Lohse, C. Hoffmann, V. Nikolaev, J. Vilardaga, and M. Bunemann. Adv Protein Chem, (2007)Lohse, Martin J Hoffmann, Carsten Nikolaev, Viacheslav O Vilardaga, Jean-Pierre Bunemann, Moritz Research Support, Non-U.S. Gov't Review United States Advances in protein chemistry Adv Protein Chem. 2007;74:167-88..
14 years ago by @pharmawuerz
show all tags
Transfer/*methods
Heterotrimeric
Humans
Fluorescence
Survival
*Signal
Animals
Receptor
G-Protein-Coupled/*chemistry/*metabolism
Proteins/chemistry/metabolism
Kinetics
GTP-Binding
Resonance
Transduction
Energy
Cell
Transfer/*methodsHeterotrimericHumansFluorescenceSurvival*SignalAnimalsReceptorG-Protein-Coupled/*chemistry/*metabolismProteins/chemistry/metabolismKineticsGTP-BindingResonanceTransductionEnergyCell
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1Fluorescence resonance energy transfer analysis of alpha 2a-adrenergic receptor activation reveals distinct agonist-specific conformational changes
A. Zurn, U. Zabel, J. Vilardaga, H. Schindelin, M. Lohse, and C. Hoffmann. Mol Pharmacol, 75 (3): 534-41 (March 2009)Zurn, A Zabel, U Vilardaga, J-P Schindelin, H Lohse, M J Hoffmann, C Comparative Study Research Support, Non-U.S. Gov't United States Molecular pharmacology Mol Pharmacol. 2009 Mar;75(3):534-41. Epub 2008 Dec 23..
14 years ago by @pharmawuerz
show all tags
Humans
effects/physiology
Octopamine/metabolism
Fluorescence
Norepinephrine/metabolism
Adrenergic
Protein
effects
Animals
Receptor
Clonidine/metabolism
Line
alpha-2/*agonists/*chemistry/metabolism
Dopamine/metabolism
Mice
Resonance
Conformation/drug
Ligands
Energy
Agonists/metabolism/*pharmacology
Binding/drug
Cell
Transfer/methods
Humanseffects/physiologyOctopamine/metabolismFluorescenceNorepinephrine/metabolismAdrenergicProteineffectsAnimalsReceptorClonidine/metabolismLinealpha-2/*agonists/*chemistry/metabolismDopamine/metabolismMiceResonanceConformation/drugLigandsEnergyAgonists/metabolism/*pharmacologyBinding/drugCellTransfer/methods
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1The amino-terminal domain of G-protein-coupled receptor kinase 2 is a regulatory Gbeta gamma binding site
T. Eichmann, K. Lorenz, M. Hoffmann, J. Brockmann, C. Krasel, M. Lohse, and U. Quitterer. J Biol Chem, 278 (10): 8052-7 (March 2003)Eichmann, Tanja Lorenz, Kristina Hoffmann, Michaela Brockmann, Jorg Krasel, Cornelius Lohse, Martin J Quitterer, Ursula Research Support, Non-U.S. Gov't United States The Journal of biological chemistry J Biol Chem. 2003 Mar 7;278(10):8052-7. Epub 2002 Dec 16..
14 years ago by @pharmawuerz
show all tags
Binding
Humans
Sites
Transfection
Proteins/metabolism
Protein
beta-Adrenergic
Receptor
Kinases
Cyclic
Proteins/chemistry/genetics/metabolism
Line
GTP-Binding
Transduction
Recombinant
Kinases/chemistry/genetics/*metabolism
Signal
AMP-Dependent
Cell
BindingHumansSitesTransfectionProteins/metabolismProteinbeta-AdrenergicReceptorKinasesCyclicProteins/chemistry/genetics/metabolismLineGTP-BindingTransductionRecombinantKinases/chemistry/genetics/*metabolismSignalAMP-DependentCell
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