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1Designing and analyzing clinical trials with composite outcomes: consideration of possible treatment differences between the individual outcomes.
J. Pogue, P. Devereaux, L. Thabane, and S. Yusuf. PloS one, 7 (4): e34785 (January 2012)6637<m:linebreak></m:linebreak>JID: 101285081; OID: NLM: PMC3328496; 2011/11/08 received; 2012/03/09 accepted; 2012/04/17 epublish; ppublish;<m:linebreak></m:linebreak>Comparacions múltiples; Composite endpoints; RCT; Heterogeneïtat.
2 years ago by @jepcastel
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BiomedicalResearch
RCT
ResearchDesign
Humans
Statistical
Models
TreatmentOutcome
BiomedicalResearchRCTResearchDesignHumansStatisticalModelsTreatmentOutcome
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1Working covariance model selection for generalized estimating equations.
V. Carey, and Y. Wang. Statistics in medicine, 30 (26): 3117-24 (November 2011)6264.
2 years ago by @jepcastel
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gamma-AminobutyricAcid:therapeuticuse
RCT
Software:statistics&numericaldata
Humans
RandomizedControlledTrialsasTopic:statistics
gamma-AminobutyricAcid:analogs&derivatives
Epilepsy
LongitudinalStudies
DataInterpretation
ComputerSimulation
Anticonvulsants
LongitudinalStudies:statistics&numericaldata
NormalDistribution
gamma-AminobutyricAcid
Anticonvulsants:therapeuticuse
Statistical
Models
Software
Epilepsy:epidemiology
gamma-AminobutyricAcid:therapeuticuseRCTSoftware:statistics&numericaldataHumansRandomizedControlledTrialsasTopic:statisticsgamma-AminobutyricAcid:analogs&derivativesEpilepsyLongitudinalStudiesDataInterpretationComputerSimulationAnticonvulsantsLongitudinalStudies:statistics&numericaldataNormalDistributiongamma-AminobutyricAcidAnticonvulsants:therapeuticuseStatisticalModelsSoftwareEpilepsy:epidemiology
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1Statistics notes: missing outcomes in randomised trials.
A. Vickers, and D. Altman. BMJ (Clinical research ed.), (January 2013)7403 JID: 8900488; epublish; Dades censurades; RCT; Introductori; Imputació múltiple.
2 years ago by @jepcastel
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DataCollection:methods
RCT
ResearchDesign
RandomizedControlledTrialsasTopic:statistics
ResearchDesign:standards
Statistical
DataCollection
DataInterpretation
TreatmentOutcome
DataCollection:methodsRCTResearchDesignRandomizedControlledTrialsasTopic:statisticsResearchDesign:standardsStatisticalDataCollectionDataInterpretationTreatmentOutcome
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1A comparison between traditional methods and multilevel regression for the analysis of multicenter intervention studies.
M. Moerbeek, G. van Breukelen, and M. Berger. Journal of clinical epidemiology, 56 (4): 341-50 (April 2003)3107<m:linebreak></m:linebreak>Multilevel.
2 years ago by @jepcastel
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RCT
ResearchDesign
Humans
Smoking:prevention&control
DataInterpretation
MulticenterStudiesasTopic:methods
Adolescent
Smoking
Statistical
Models
RegressionAnalysis
Child
MulticenterStudiesasTopic
TreatmentOutcome
ClusterAnalysis
RCTResearchDesignHumansSmoking:prevention&controlDataInterpretationMulticenterStudiesasTopic:methodsAdolescentSmokingStatisticalModelsRegressionAnalysisChildMulticenterStudiesasTopicTreatmentOutcomeClusterAnalysis
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1Listen to the data when results are not significant.
C. Hewitt, N. Mitchell, and D. Torgerson. BMJ (Clinical research ed.), 336 (7634): 23-5 (January 2008)4863<m:linebreak></m:linebreak>LR: 20081120; JID: 8900488; 0 (Abortifacient Agents, Nonsteroidal); 0 (Anesthetics, Local); 137-58-6 (Lidocaine); 59122-46-2 (Misoprostol); OID: NLM: PMC2174757; ppublish; Exemples de recomanacions en sentit contrari als resultats<m:linebreak></m:linebreak>Presentació de dades; Interpretació de resultats.
2 years ago by @jepcastel
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Nonsteroidal:administration&dosage
Administration
Evidence-BasedMedicine
Lidocaine:administration&dosage
Local
DataInterpretation
Anesthetics
Inhalation
Pregnancy
Adolescent
Misoprostol:administration&dosage
Induced
Induced:methods
Statistical
Bias(Epidemiology)
Local:administration&dosage
Lidocaine
RCT
Humans
RandomizedControlledTrialsasTopic:statistics
WoundsandInjuries:prevention&control
EquipmentSafety
Oral
Infant
Misoprostol
WoundsandInjuries
Nonsteroidal
Pain
Labor
AbortifacientAgents
SexEducation:statistics&numericaldata
Pain:prevention&control
SexEducation
Female
Nonsteroidal:administration&dosageAdministrationEvidence-BasedMedicineLidocaine:administration&dosageLocalDataInterpretationAnestheticsInhalationPregnancyAdolescentMisoprostol:administration&dosageInducedInduced:methodsStatisticalBias(Epidemiology)Local:administration&dosageLidocaineRCTHumansRandomizedControlledTrialsasTopic:statisticsWoundsandInjuries:prevention&controlEquipmentSafetyOralInfantMisoprostolWoundsandInjuriesNonsteroidalPainLaborAbortifacientAgentsSexEducation:statistics&numericaldataPain:prevention&controlSexEducationFemale
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1Design of Major Randomized Trials: Part 3 of a 4-Part Series on Statistics for Clinical Trials.
S. Pocock, T. Clayton, and G. Stone. Journal of the American College of Cardiology, 66 (24): 2757-66 (December 2015)Disseny; RCT; Introductori; CV Exemples i gràfics.
2 years ago by @jepcastel
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RCT
PatientSelection
Humans
RandomizedControlledTrialsasTopic:statistics
Statistical
CardiovascularDiseases:therapy
DataInterpretation
CardiovascularDiseases
RCTPatientSelectionHumansRandomizedControlledTrialsasTopic:statisticsStatisticalCardiovascularDiseases:therapyDataInterpretationCardiovascularDiseases
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1When is a further clinical trial justified?
M. Ferreira, R. Herbert, M. Crowther, A. Verhagen, and A. Sutton. BMJ (Clinical research ed.), (January 2012)7186<m:linebreak></m:linebreak>JID: 8900488; epublish;<m:linebreak></m:linebreak>MDCI; RCT; Relació benefici/risc; Metaanàlisi.
2 years ago by @jepcastel
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Meta-AnalysisasTopic
RCT
ChronicPain
ExerciseTherapy
ResearchDesign
BackPain:rehabilitation
Humans
RandomizedControlledTrialsasTopic:statistics
Statistical
DataInterpretation
BackPain
Meta-AnalysisasTopicRCTChronicPainExerciseTherapyResearchDesignBackPain:rehabilitationHumansRandomizedControlledTrialsasTopic:statisticsStatisticalDataInterpretationBackPain
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1Ophthalmic Statistics Note 4: analysing data from randomised controlled trials with baseline and follow-up measurements.
R. Nash, C. Bunce, N. Freemantle, C. Doré, and C. Rogers. The British journal of ophthalmology, 98 (11): 1467-9 (November 2014)Anàlisi de dades; Canvi.
2 years ago by @jepcastel
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Follow-UpStudies
RCT
VascularEndothelialGrowthFactorA
Humans
AngiogenesisInhibitors:therapeuticuse
Humanized
Antibodies
DataInterpretation
MacularDegeneration:drugtherapy
VisualAcuity:physiology
VisualAcuity:drugeffects
MacularDegeneration
Monoclonal
VascularEndothelialGrowthFactorA:antagonists
Statistical
Humanized:therapeuticuse
AngiogenesisInhibitors
MacularDegeneration:physiopathology
VisualAcuity
Follow-UpStudiesRCTVascularEndothelialGrowthFactorAHumansAngiogenesisInhibitors:therapeuticuseHumanizedAntibodiesDataInterpretationMacularDegeneration:drugtherapyVisualAcuity:physiologyVisualAcuity:drugeffectsMacularDegenerationMonoclonalVascularEndothelialGrowthFactorA:antagonistsStatisticalHumanized:therapeuticuseAngiogenesisInhibitorsMacularDegeneration:physiopathologyVisualAcuity
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1A primer on the design, conduct, and interpretation of clinical trials.
L. Appel. Clinical journal of the American Society of Nephrology : CJASN, 1 (6): 1360-7 (November 2006)5015<m:linebreak></m:linebreak>LR: 20071115; JID: 101271570; 2006/10/11 aheadofprint; ppublish;<m:linebreak></m:linebreak>Disseny; Introductori; RCT; Nefrologia.
2 years ago by @jepcastel
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FactorAnalysis
RandomizedControlledTrialsasTopic:standards
RCT
PatientSelection
ResearchDesign
Humans
ClinicalTrialsasTopic:standards
Statistical
ClinicalTrialsasTopic
ClinicalTrialsasTopic:methods
FactorAnalysisRandomizedControlledTrialsasTopic:standardsRCTPatientSelectionResearchDesignHumansClinicalTrialsasTopic:standardsStatisticalClinicalTrialsasTopicClinicalTrialsasTopic:methods
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1Statistics for clinicians: An introduction to logistic regression.
M. Wiest, K. Lee, and J. Carlin. Journal of paediatrics and child health, 51 (7): 670-3 (July 2015)Regressió logística; Introductori; Pediatria.
2 years ago by @jepcastel
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Premature
RCT
Humans
RespiratoryDistressSyndrome
Risk
Newborn:therapy
ContinuousPositiveAirwayPressure
Infant
LogisticModels
Intratracheal
DataInterpretation
Newborn
OddsRatio
Statistical
Intubation
TreatmentOutcome
PrematureRCTHumansRespiratoryDistressSyndromeRiskNewborn:therapyContinuousPositiveAirwayPressureInfantLogisticModelsIntratrachealDataInterpretationNewbornOddsRatioStatisticalIntubationTreatmentOutcome
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1Statistics notes: Analysing controlled trials with baseline and follow up measurements.
A. Vickers, and D. Altman. BMJ (Clinical research ed.), 323 (7321): 1123-1124 (November 2001)2761 Estadístics.
2 years ago by @jepcastel
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ChronicDisease:therapy
Follow-UpStudies
AnalysisofVariance
RCT
Humans
ShoulderPain
ShoulderPain:therapy
AcupunctureAnalgesia
Statistical
DataInterpretation
ChronicDisease
ChronicDisease:therapyFollow-UpStudiesAnalysisofVarianceRCTHumansShoulderPainShoulderPain:therapyAcupunctureAnalgesiaStatisticalDataInterpretationChronicDisease
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1Interpretation and inference in noninferiority randomized controlled trials in drug research.
G. Wangge, O. Klungel, K. Roes, A. de Boer, A. Hoes, and M. Knol. Clinical pharmacology and therapeutics, 88 (3): 420-3 (September 2010)5991<m:linebreak></m:linebreak>JID: 0372741; 0 (Pharmaceutical Preparations); 2010/07/28 aheadofprint; ppublish;<m:linebreak></m:linebreak>Tests d'equivalència; Tipus d'estudis; Introductori.
2 years ago by @jepcastel
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PharmaceuticalPreparations:administration&dosa
TherapeuticEquivalency
RCT
PharmaceuticalPreparations:metabolism
ResearchDesign
Humans
Statistical
PharmaceuticalPreparations
DataInterpretation
PharmaceuticalPreparations:administration&dosaTherapeuticEquivalencyRCTPharmaceuticalPreparations:metabolismResearchDesignHumansStatisticalPharmaceuticalPreparationsDataInterpretation
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1Evolving statistical methods to facilitate evaluation of the causal association between erythropoiesis-stimulating agent dose and mortality in nonexperimental research: strengths and limitations.
B. Bradbury, M. Brookhart, W. Winkelmayer, C. Critchlow, R. Kilpatrick, M. Joffe, H. Feldman, J. Acquavella, O. Wang, and K. Rothman. American journal of kidney diseases : the official journal of the National Kidney Foundation, 54 (3): 554-60 (September 2009)5279<m:linebreak></m:linebreak>JID: 8110075; 0 (Hematinics); RF: 40; 2008/12/19 received; 2009/05/06 accepted; 2009/07/09 aheadofprint; ppublish;.
2 years ago by @jepcastel
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Hematinics
DrugEvaluation:mortality
RCT
Humans
Hematinics:administration&dosage
Mortality
Hematinics:adverseeffects
DrugEvaluation
BiomedicalResearch
BiomedicalResearch:methods
DrugEvaluation:methods
RandomizedControlledTrialsasTopic:mortality
Statistical
Models
HematinicsDrugEvaluation:mortalityRCTHumansHematinics:administration&dosageMortalityHematinics:adverseeffectsDrugEvaluationBiomedicalResearchBiomedicalResearch:methodsDrugEvaluation:methodsRandomizedControlledTrialsasTopic:mortalityStatisticalModels
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1Reporting attrition in randomised controlled trials.
J. Dumville, D. Torgerson, and C. Hewitt. BMJ (Clinical research ed.), 332 (7547): 969-71 (April 2006)4285<m:linebreak></m:linebreak>LR: 20071115; PUBM: Print; JID: 8900488; RF: 11; ppublish;<m:linebreak></m:linebreak>Generalització.
2 years ago by @jepcastel
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RandomizedControlledTrialsasTopic:standards
Follow-UpStudies
RCT
ResearchDesign
RandomizedControlledTrialsasTopic:statistics
ResearchDesign:standards
PatientDropouts
Statistical
Bias(Epidemiology)
DataInterpretation
RandomizedControlledTrialsasTopic:standardsFollow-UpStudiesRCTResearchDesignRandomizedControlledTrialsasTopic:statisticsResearchDesign:standardsPatientDropoutsStatisticalBias(Epidemiology)DataInterpretation
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1Using numerical results from systematic reviews in clinical practice.
H. McQuay, and R. Moore. Annals of internal medicine, 126 (9): 712-20 (May 1997)3010<m:linebreak></m:linebreak>Mesures de contrast.
2 years ago by @jepcastel
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RCT
ReviewLiteratureasTopic
Humans
Statistical
DataInterpretation
RCTReviewLiteratureasTopicHumansStatisticalDataInterpretation
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1Demystifying trial networks and network meta-analysis.
E. Mills, K. Thorlund, and J. Ioannidis. BMJ (Clinical research ed.), (January 2013)7326 JID: 8900488; epublish; Network meta-analysis; Introductori.
2 years ago by @jepcastel
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Meta-AnalysisasTopic
RCT
ResearchDesign
Humans
Male
Statistical
Ontario
DataInterpretation
SensitivityandSpecificity
Female
InformationServices
Meta-AnalysisasTopicRCTResearchDesignHumansMaleStatisticalOntarioDataInterpretationSensitivityandSpecificityFemaleInformationServices
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1In search of fewer independent risk factors.
D. Brotman, E. Walker, M. Lauer, and R. O'Brien. Archives of internal medicine, 165 (2): 138-45 (January 2005)3841<m:linebreak></m:linebreak>Mesures d'associació.
2 years ago by @jepcastel
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CardiovascularDiseases:epidemiology
RCT
Humans
Male
AgeFactors
MultivariateAnalysis
PredictiveValueofTests
EpidemiologicMethods
RiskFactors
OddsRatio
Statistical
Models
ConfoundingFactors(Epidemiology)
CardiovascularDiseases:diagnosis
SensitivityandSpecificity
SexFactors
Female
CardiovascularDiseases
CardiovascularDiseases:epidemiologyRCTHumansMaleAgeFactorsMultivariateAnalysisPredictiveValueofTestsEpidemiologicMethodsRiskFactorsOddsRatioStatisticalModelsConfoundingFactors(Epidemiology)CardiovascularDiseases:diagnosisSensitivityandSpecificitySexFactorsFemaleCardiovascularDiseases
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1Impact of allocation concealment on conclusions drawn from meta-analyses of randomized trials.
J. Pildal, A. Hróbjartsson, K. Jørgensen, J. Hilden, D. Altman, and P. Gøtzsche. International journal of epidemiology, 36 (4): 847-57 (August 2007)5316<m:linebreak></m:linebreak>LR: 20080616; JID: 7802871; EIN: Int J Epidemiol. 2008 Apr;37(2):422; 2007/05/21 aheadofprint; ppublish;<m:linebreak></m:linebreak>Metaanàlisi.
2 years ago by @jepcastel
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Meta-AnalysisasTopic
Double-BlindMethod
RCT
Humans
Single-BlindMethod
Statistical
Bias(Epidemiology)
DataInterpretation
TreatmentOutcome
SensitivityandSpecificity
Meta-AnalysisasTopicDouble-BlindMethodRCTHumansSingle-BlindMethodStatisticalBias(Epidemiology)DataInterpretationTreatmentOutcomeSensitivityandSpecificity
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1Real longitudinal data analysis for real people: building a good enough mixed model.
J. Cheng, L. Edwards, M. Maldonado-Molina, K. Komro, and K. Muller. Statistics in medicine, 29 (4): 504-20 (February 2010)5490<m:linebreak></m:linebreak>CP: Copyright © 2009 John Wiley & Sons, Ltd.; PN: 0277-6715;<m:linebreak></m:linebreak>Mixed models.
2 years ago by @jepcastel
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RCT
Humans
Chicago
RandomizedControlledTrialsasTopic:statistics
LongitudinalStudies
AfricanAmericans:statistics&numericaldata
EuropeanContinentalAncestryGroup
AfricanAmericans
AlcoholDrinking
MultivariateAnalysis
LinearModels
AlcoholDrinking:prevention&control
Adolescent
EuropeanContinentalAncestryGroup:statistics&
HispanicAmericans:statistics&numericaldata
Statistical
Models
Child
HispanicAmericans
RCTHumansChicagoRandomizedControlledTrialsasTopic:statisticsLongitudinalStudiesAfricanAmericans:statistics&numericaldataEuropeanContinentalAncestryGroupAfricanAmericansAlcoholDrinkingMultivariateAnalysisLinearModelsAlcoholDrinking:prevention&controlAdolescentEuropeanContinentalAncestryGroup:statistics&HispanicAmericans:statistics&numericaldataStatisticalModelsChildHispanicAmericans
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1Interpreting the results of patient reported outcome measures in clinical trials: the clinician's perspective.
H. Schünemann, E. Akl, and G. Guyatt. Health and quality of life outcomes, (January 2006)4487<m:linebreak></m:linebreak>LR: 20071115; PUBM: Electronic; JID: 101153626; PMC: PMC1584217; 2006/08/02 received; 2006/09/14 accepted; 2006/09/14 aheadofprint; epublish;<m:linebreak></m:linebreak>MDCI.
2 years ago by @jepcastel
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RiskAssessment
RCT
Humans
RandomizedControlledTrialsasTopic:statistics
OutcomeAssessment(HealthCare):methods
OutcomeAssessment(HealthCare)
DataInterpretation
DecisionSupportTechniques
OutcomeAssessment(HealthCare):statistics&num
QualityofLife
SicknessImpactProfile
Judgment
Statistical
RegressionAnalysis
RiskAssessmentRCTHumansRandomizedControlledTrialsasTopic:statisticsOutcomeAssessment(HealthCare):methodsOutcomeAssessment(HealthCare)DataInterpretationDecisionSupportTechniquesOutcomeAssessment(HealthCare):statistics&numQualityofLifeSicknessImpactProfileJudgmentStatisticalRegressionAnalysis
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1Designing and analyzing clinical trials with composite outcomes: consideration of possible treatment differences between the individual outcomes.

1Working covariance model selection for generalized estimating equations.

1Statistics notes: missing outcomes in randomised trials.

1A comparison between traditional methods and multilevel regression for the analysis of multicenter intervention studies.

1Listen to the data when results are not significant.

1Design of Major Randomized Trials: Part 3 of a 4-Part Series on Statistics for Clinical Trials.

1When is a further clinical trial justified?

1Ophthalmic Statistics Note 4: analysing data from randomised controlled trials with baseline and follow-up measurements.

1A primer on the design, conduct, and interpretation of clinical trials.

1Statistics for clinicians: An introduction to logistic regression.

1Statistics notes: Analysing controlled trials with baseline and follow up measurements.

1Interpretation and inference in noninferiority randomized controlled trials in drug research.

1Evolving statistical methods to facilitate evaluation of the causal association between erythropoiesis-stimulating agent dose and mortality in nonexperimental research: strengths and limitations.

1Reporting attrition in randomised controlled trials.

1Using numerical results from systematic reviews in clinical practice.

1Demystifying trial networks and network meta-analysis.

1In search of fewer independent risk factors.

1Impact of allocation concealment on conclusions drawn from meta-analyses of randomized trials.

1Real longitudinal data analysis for real people: building a good enough mixed model.

1Interpreting the results of patient reported outcome measures in clinical trials: the clinician's perspective.

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publications (hide)20
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