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1Dual regulation of the parathyroid hormone (PTH)/PTH-related peptide receptor signaling by protein kinase C and beta-arrestins
M. Castro, F. Dicker, J. Vilardaga, C. Krasel, M. Bernhardt, and M. Lohse. Endocrinology, 143 (10): 3854-65 (October 2002)Castro, Marian Dicker, Frank Vilardaga, Jean-Pierre Krasel, Cornelius Bernhardt, Manfred Lohse, Martin J Research Support, Non-U.S. Gov't United States Endocrinology Endocrinology. 2002 Oct;143(10):3854-65..
14 years ago by @pharmawuerz
show all tags
Inositol
Arrestins/pharmacology/*physiology
COS
Messenger
Protein
1
Type
Animals
Receptor
Second
Cyclic
Kinase
Systems/physiology
C/*physiology
Fragments/metabolism
Hormone/chemistry/metabolism/*physiology
Hormone,
Hormone/pharmacology
AMP/physiology
Phosphates/physiology
Phosphotransferases/physiology
Transduction/*physiology
Parathyroid
Peptide
Signal
Cell
InositolArrestins/pharmacology/*physiologyCOSMessengerProtein1TypeAnimalsReceptorSecondCyclicKinaseSystems/physiologyC/*physiologyFragments/metabolismHormone/chemistry/metabolism/*physiologyHormone,Hormone/pharmacologyAMP/physiologyPhosphates/physiologyPhosphotransferases/physiologyTransduction/*physiologyParathyroidPeptideSignalCell
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1Turn-on switch in parathyroid hormone receptor by a two-step parathyroid hormone binding mechanism
M. Castro, V. Nikolaev, D. Palm, M. Lohse, and J. Vilardaga. Proc Natl Acad Sci U S A, 102 (44): 16084-9 (November 2005)Castro, Marian Nikolaev, Viacheslav O Palm, Dieter Lohse, Martin J Vilardaga, Jean-Pierre Research Support, Non-U.S. Gov't United States Proceedings of the National Academy of Sciences of the United States of America Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):16084-9. Epub 2005 Oct 18..
14 years ago by @pharmawuerz
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Binding
Dyes
Structure,
Hormone,
Humans
Tertiary
1/chemistry/*metabolism
Fluorescence
Protein
Type
Receptor
Fluorescent
Kinetics
Transfer
Resonance
Energy
Parathyroid
Hormone/metabolism
BindingDyesStructure,Hormone,HumansTertiary1/chemistry/*metabolismFluorescenceProteinTypeReceptorFluorescentKineticsTransferResonanceEnergyParathyroidHormone/metabolism
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1Measurement of the millisecond activation switch of G protein-coupled receptors in living cells
J. Vilardaga, M. Bunemann, C. Krasel, M. Castro, and M. Lohse. Nat Biotechnol, 21 (7): 807-12 (July 2003)Vilardaga, Jean-Pierre Bunemann, Moritz Krasel, Cornelius Castro, Marian Lohse, Martin J Comparative Study Research Support, Non-U.S. Gov't United States Nature biotechnology Nat Biotechnol. 2003 Jul;21(7):807-12. Epub 2003 Jun 15..
14 years ago by @pharmawuerz
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Binding
Clonidine/pharmacology
Proteins/*chemistry/*metabolism
&
Spectrometry,
G-Protein-Coupled/agonists/antagonists
1/agonists/antagonists
Protein
Type
inhibitors/metabolism
Receptor
Line
effects/metabolism
inhibitors/chemistry
Hormone,
inhibitors/*chemistry/*metabolism
Humans
Hormone/pharmacology
Adrenergic
Techniques/*methods
Fluorescence/*methods
alpha-2/agonists/antagonists
Kidney/chemistry/drug
Transduction/*physiology
GTP-Binding
Parathyroid
Signal
Culture
Cell
BindingClonidine/pharmacologyProteins/*chemistry/*metabolism&Spectrometry,G-Protein-Coupled/agonists/antagonists1/agonists/antagonistsProteinTypeinhibitors/metabolismReceptorLineeffects/metabolisminhibitors/chemistryHormone,inhibitors/*chemistry/*metabolismHumansHormone/pharmacologyAdrenergicTechniques/*methodsFluorescence/*methodsalpha-2/agonists/antagonistsKidney/chemistry/drugTransduction/*physiologyGTP-BindingParathyroidSignalCultureCell
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1Site-specific, orthogonal labeling of proteins in intact cells with two small biarsenical fluorophores
A. Zurn, C. Klenk, U. Zabel, S. Reiner, M. Lohse, and C. Hoffmann. Bioconjug Chem, 21 (5): 853-9 (May 2010)Zurn, Alexander Klenk, Christoph Zabel, Ulrike Reiner, Susanne Lohse, Martin J Hoffmann, Carsten Research Support, Non-U.S. Gov't United States Bioconjugate chemistry Bioconjug Chem. 2010 May 19;21(5):853-9..
14 years ago by @pharmawuerz
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Binding
Transfer/*methods
Acid
Hormone,
Humans
Data
Sequence
Fluorescence
Arrestins/analysis/chemistry/metabolism
Protein
Type
1/analysis/chemistry/metabolism
Receptor
Molecular
Proteins/*analysis/chemistry/*metabolism
Line
Fluorescent
Resonance
Amino
Energy
Parathyroid
Dyes/*chemistry/metabolism
Cell
BindingTransfer/*methodsAcidHormone,HumansDataSequenceFluorescenceArrestins/analysis/chemistry/metabolismProteinType1/analysis/chemistry/metabolismReceptorMolecularProteins/*analysis/chemistry/*metabolismLineFluorescentResonanceAminoEnergyParathyroidDyes/*chemistry/metabolismCell
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1Formation of a ternary complex among NHERF1, beta-arrestin, and parathyroid hormone receptor
C. Klenk, T. Vetter, A. Zurn, J. Vilardaga, P. Friedman, B. Wang, and M. Lohse. J Biol Chem, 285 (39): 30355-62 (September 2010)Klenk, Christoph Vetter, Thorsten Zurn, Alexander Vilardaga, Jean-Pierre Friedman, Peter A Wang, Bin Lohse, Martin J DK069998/DK/NIDDK NIH HHS/United States DK087688/DK/NIDDK NIH HHS/United States DK54171/DK/NIDDK NIH HHS/United States Research Support, N.I.H., Extramural United States The Journal of biological chemistry J Biol Chem. 2010 Sep 24;285(39):30355-62. Epub 2010 Jul 23..
14 years ago by @pharmawuerz
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Structure,
Sodium-Hydrogen
Cricetinae
Hormone,
Cricetulus
Humans
Quaternary
CHO
Multiprotein
Antiporter/genetics/*metabolism
Protein
Type
Arrestins/genetics/*metabolism
Animals
Receptor
Transduction/physiology
Phosphoproteins/genetics/*metabolism
Complexes/genetics/*metabolism
Parathyroid
Signal
1/genetics/*metabolism
Cell
Structure,Sodium-HydrogenCricetinaeHormone,CricetulusHumansQuaternaryCHOMultiproteinAntiporter/genetics/*metabolismProteinTypeArrestins/genetics/*metabolismAnimalsReceptorTransduction/physiologyPhosphoproteins/genetics/*metabolismComplexes/genetics/*metabolismParathyroidSignal1/genetics/*metabolismCell
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2Agonist-regulated cleavage of the extracellular domain of parathyroid hormone receptor type 1
C. Klenk, S. Schulz, D. Calebiro, and M. Lohse. J Biol Chem, 285 (12): 8665-74 (March 2010)Klenk, Christoph Schulz, Stefan Calebiro, Davide Lohse, Martin J Research Support, Non-U.S. Gov't United States The Journal of biological chemistry J Biol Chem. 2010 Mar 19;285(12):8665-74. Epub 2010 Jan 15..
14 years ago by @pharmawuerz
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Binding
Structure,
Cricetinae
Tertiary
Epitopes/chemistry
Rats
Protein
Type
Animals
Receptor
DNA,
G-Protein-Coupled/chemistry
Line,
Regulation
Expression
Ligands
Hormone,
1/*agonists/*chemistry
Exons
Disulfides
Cricetulus
Humans
CHO
Post-Translational
Gene
Tumor
Parathyroid
Complementary/metabolism
Processing,
Cell
BindingStructure,CricetinaeTertiaryEpitopes/chemistryRatsProteinTypeAnimalsReceptorDNA,G-Protein-Coupled/chemistryLine,RegulationExpressionLigandsHormone,1/*agonists/*chemistryExonsDisulfidesCricetulusHumansCHOPost-TranslationalGeneTumorParathyroidComplementary/metabolismProcessing,Cell
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1Differential conformational requirements for activation of G proteins and the regulatory proteins arrestin and G protein-coupled receptor kinase in the G protein-coupled receptor for parathyroid hormone (PTH)/PTH-related protein
J. Vilardaga, M. Frank, C. Krasel, C. Dees, R. Nissenson, and M. Lohse. J Biol Chem, 276 (36): 33435-43 (September 2001)Vilardaga, J P Frank, M Krasel, C Dees, C Nissenson, R A Lohse, M J Research Support, Non-U.S. Gov't United States The Journal of biological chemistry J Biol Chem. 2001 Sep 7;276(36):33435-43. Epub 2001 May 31..
14 years ago by @pharmawuerz
show all tags
COS
Protein-Serine-Threonine
Competitive
Inhibitory
Kinetics
Mutation
Conformation
Factors
Compounds/pharmacology
Hormone/*metabolism
Hormone,
Activation
Immunoblotting
Ions/metabolism
Chlorides/pharmacology
Time
Arrestin/*metabolism
Dose-Response
50
Relationship,
Phosphates/metabolism
Cell
Histidine/chemistry
Binding
Inositol
Sites
Zinc
Concentration
Membrane/metabolism
Protein
1
Type
Animals
Receptor
Cyclic
Kinases/*metabolism
Zinc/metabolism
Transduction
Ligands
AMP/metabolism
Phosphorylation
Binding,
Arrestins/metabolism
Proteins/metabolism
GTP-Binding
Enzyme
Parathyroid
Signal
Drug
COSProtein-Serine-ThreonineCompetitiveInhibitoryKineticsMutationConformationFactorsCompounds/pharmacologyHormone/*metabolismHormone,ActivationImmunoblottingIons/metabolismChlorides/pharmacologyTimeArrestin/*metabolismDose-Response50Relationship,Phosphates/metabolismCellHistidine/chemistryBindingInositolSitesZincConcentrationMembrane/metabolismProtein1TypeAnimalsReceptorCyclicKinases/*metabolismZinc/metabolismTransductionLigandsAMP/metabolismPhosphorylationBinding,Arrestins/metabolismProteins/metabolismGTP-BindingEnzymeParathyroidSignalDrug
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1Immunohistochemical identification of the PTHR1 parathyroid hormone receptor in normal and neoplastic human tissues
A. Lupp, C. Klenk, C. Rocken, M. Evert, C. Mawrin, and S. Schulz. Eur J Endocrinol, 162 (5): 979-86 (May 2010)Lupp, Amelie Klenk, Christoph Rocken, Christoph Evert, Matthias Mawrin, Christian Schulz, Stefan England European journal of endocrinology / European Federation of Endocrine Societies Eur J Endocrinol. 2010 May;162(5):979-86. Epub 2010 Feb 15..
14 years ago by @pharmawuerz
show all tags
Colorectal
Cricetinae
Neoplasms/chemistry
Osteosarcoma/chemistry
Prostatic
Type
Animals
Receptor
Carcinoma,
Bones/chemistry
Intestines/chemistry
Bone
Cell/chemistry
Hormone,
Cricetulus
Humans
Immunohistochemistry
Male
CHO
Kidney/chemistry
Renal
1/*analysis/immunology
and
Parathyroid
Cell
ColorectalCricetinaeNeoplasms/chemistryOsteosarcoma/chemistryProstaticTypeAnimalsReceptorCarcinoma,Bones/chemistryIntestines/chemistryBoneCell/chemistryHormone,CricetulusHumansImmunohistochemistryMaleCHOKidney/chemistryRenal1/*analysis/immunologyandParathyroidCell
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1Buffering of calcium in the vicinity of a channel pore.
M. Stern. Cell Calcium, 13 (3): 183-92 (March 1992)
16 years ago by @hake
show all tags
Lactation,
Human
Calcium,
Biological,
Products,
Rumen,
Superoxide
Rhodamines,
Animal
Thiourea,
Sodium
Indoles,
Inbred
Animals,
Oxygen,
Calcium
Hormone,
Female,
Growth
Research
Cells,
Naphthols,
Thiazoles,
Dismutase,
Hypoxia,
Vitro,
U.S.
Concentration,
Fish
Fluorescent
Membrane
Soybeans,
Buffers,
Cell
Piperidines,
Hydrogen-Ion
Feed,
Calibration,
Cytosol,
Channels,
Contraction,
Potentials,
Support,
Rats,
Extracellular
Reticulum,
Ischemia,
P.H.S.,
Sodium,
ATPase,
Survival,
Models,
Space,
Benzofurans,
{N}a$^{+}$-{K}$^{+}$-Exchanging
In
Mitochondria,
Myocardium,
Cardiovascular,
Sarcoplasmic
Strains,
Dietary
Gov't,
1315621
Comparative
Diffusion,
Cyclic,
Kinetics,
Proteins,
Esterification,
Digestion,
Non-U.S.
Myocardial
Mathematics,
Ethers,
Study,
Dyes,
Cultured,
Heart,
Lactation,HumanCalcium,Biological,Products,Rumen,SuperoxideRhodamines,AnimalThiourea,SodiumIndoles,InbredAnimals,Oxygen,CalciumHormone,Female,GrowthResearchCells,Naphthols,Thiazoles,Dismutase,Hypoxia,Vitro,U.S.Concentration,FishFluorescentMembraneSoybeans,Buffers,CellPiperidines,Hydrogen-IonFeed,Calibration,Cytosol,Channels,Contraction,Potentials,Support,Rats,ExtracellularReticulum,Ischemia,P.H.S.,Sodium,ATPase,Survival,Models,Space,Benzofurans,{N}a$^{+}$-{K}$^{+}$-ExchangingInMitochondria,Myocardium,Cardiovascular,SarcoplasmicStrains,DietaryGov't,1315621ComparativeDiffusion,Cyclic,Kinetics,Proteins,Esterification,Digestion,Non-U.S.MyocardialMathematics,Ethers,Study,Dyes,Cultured,Heart,
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1Theory of excitation-contraction coupling in cardiac muscle.
M. Stern. Biophys. J., 63 (2): 497-517 (August 1992)
16 years ago by @hake
show all tags
Lactation,
Human
Calcium,
Products,
Rumen,
Animal
Sodium
Indoles,
Animals,
Calcium
Hormone,
Female,
Growth
Research
Cells,
Thiazoles,
Hypoxia,
U.S.
Concentration,
Fish
Membrane
Soybeans,
Cell
Piperidines,
Hydrogen-Ion
Feed,
Cytosol,
Channels,
Contraction,
Potentials,
Support,
Rats,
Reticulum,
Ischemia,
P.H.S.,
Sodium,
ATPase,
Models,
Benzofurans,
{N}a$^{+}$-{K}$^{+}$-Exchanging
Mitochondria,
Myocardium,
11203466
Cardiovascular,
Sarcoplasmic
Dietary
Gov't,
Comparative
Cyclic,
Kinetics,
Proteins,
Digestion,
Non-U.S.
Myocardial
Mathematics,
Ethers,
Study,
Cultured,
Heart,
Lactation,HumanCalcium,Products,Rumen,AnimalSodiumIndoles,Animals,CalciumHormone,Female,GrowthResearchCells,Thiazoles,Hypoxia,U.S.Concentration,FishMembraneSoybeans,CellPiperidines,Hydrogen-IonFeed,Cytosol,Channels,Contraction,Potentials,Support,Rats,Reticulum,Ischemia,P.H.S.,Sodium,ATPase,Models,Benzofurans,{N}a$^{+}$-{K}$^{+}$-ExchangingMitochondria,Myocardium,11203466Cardiovascular,SarcoplasmicDietaryGov't,ComparativeCyclic,Kinetics,Proteins,Digestion,Non-U.S.MyocardialMathematics,Ethers,Study,Cultured,Heart,
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publications (hide)11 displayallpublications onlypublications per page5102050100 sort byadded attitleauthorpublication dateentry typehelp for advanced sorting... RSSBibTeXRDFmore...

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publications (hide)11
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