M. > Membrane protein

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1Mitochondrial Protein Translocation-Associated Degradation.
C. M\aartensson, C. Priesnitz, J. Song, L. Ellenrieder, K. Doan, F. Boos, A. Floerchinger, N. Zufall, S. Oeljeklaus, B. Warscheid and 1 other author(s). Nature, 569 (7758): 679--683 (May 2019)
6 months ago by @warscheidlab
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Proteins,Mitochondrial
Proteins/*metabolism,Protein
Import
Proteins/metabolism,Saccharomyces
Degradation,Membrane
*Proteolysis,Carrier
Precursor
Protein
Complex
Containing
Proteins/metabolism,Mitochondria/*metabolism,Mitochondrial
Membrane
Proteins/metabolism,Endoplasmic
Proteins/metabolism,Mitochondrial
cerevisiae
cerevisiae/*cytology/*metabolism,to_read,Valosin
Reticulum-Associated
Transport
Transport,Saccharomyces
Protein/metabolism
Proteins,MitochondrialProteins/*metabolism,ProteinImportProteins/metabolism,SaccharomycesDegradation,Membrane*Proteolysis,CarrierPrecursorProteinComplexContainingProteins/metabolism,Mitochondria/*metabolism,MitochondrialMembraneProteins/metabolism,EndoplasmicProteins/metabolism,Mitochondrialcerevisiaecerevisiae/*cytology/*metabolism,to_read,ValosinReticulum-AssociatedTransportTransport,SaccharomycesProtein/metabolism
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1Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans
B. Bielesz, Y. Sirin, H. Si, T. Niranjan, A. Gruenwald, S. Ahn, H. Kato, J. Pullman, M. Gessler, V. Haase and 1 other author(s). J Clin Invest, 120 (11): 4040--4054 (2010)
12 years ago by @ebch
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Peptides;Proteins/genetics/metabolism
Receptor;Notch1/genetics/*metabolism
Secretases/antagonists
Kidney/cytology/*metabolism/*pathology
Mice;Transgenic
Proliferation
{\&}
Protein
Signaling
Animals
Failure;Chronic/metabolism/pathology
Homeodomain
Mice
Epithelial
inhibitors
Factors/genetics/metabolism
Basic
Fibrosis/pathology
Humans
Helix-Loop-Helix
Intercellular
Transcription
Male
Calcium-Binding
Kidney
Proteins/genetics/metabolism
Precursor
Transduction/*physiology
Membrane
Nephritis;Interstitial/metabolism/pathology
Amyloid
Signal
Cell
Cells/cytology/*metabolism
Tubules/*cytology
Peptides;Proteins/genetics/metabolismReceptor;Notch1/genetics/*metabolismSecretases/antagonistsKidney/cytology/*metabolism/*pathologyMice;TransgenicProliferation{\&}ProteinSignalingAnimalsFailure;Chronic/metabolism/pathologyHomeodomainMiceEpithelialinhibitorsFactors/genetics/metabolismBasicFibrosis/pathologyHumansHelix-Loop-HelixIntercellularTranscriptionMaleCalcium-BindingKidneyProteins/genetics/metabolismPrecursorTransduction/*physiologyMembraneNephritis;Interstitial/metabolism/pathologyAmyloidSignalCellCells/cytology/*metabolismTubules/*cytology
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1Cloning and expression analysis of the mouse stroma marker Snep encoding a novel nidogen domain protein
C. Leimeister, N. Schumacher, H. Diez, and M. Gessler. Dev Dyn, 230 (2): 371--377 (2004)
12 years ago by @ebch
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Cloning;Molecular
Profiling
Embryonic
Stromal
Data
Sequence
Glycoproteins/*chemistry
Extracellular
*Gene
Protein
Proteins/*chemistry/*genetics
Animals
Matrix
Molecular
Kidney/cytology/embryology/metabolism
Cells/metabolism
Gene
Membrane
Structure;Tertiary
Mice
Expression
Regulation;Developmental
RNA;Messenger/genetics/metabolism
Development/genetics
Cloning;MolecularProfilingEmbryonicStromalDataSequenceGlycoproteins/*chemistryExtracellular*GeneProteinProteins/*chemistry/*geneticsAnimalsMatrixMolecularKidney/cytology/embryology/metabolismCells/metabolismGeneMembraneStructure;TertiaryMiceExpressionRegulation;DevelopmentalRNA;Messenger/genetics/metabolismDevelopment/genetics
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1Oscillating expression of c-Hey2 in the presomitic mesoderm suggests that the segmentation clock may use combinatorial signaling through multiple interacting bHLH factors
C. Leimeister, K. Dale, A. Fischer, B. Klamt, M. Hrabe de Angelis, F. Radtke, M. McGrew, O. Pourquie, and M. Gessler. Dev Biol, 227 (1): 91--103 (2000)
12 years ago by @ebch
show all tags
RNA;Messenger/analysis/genetics
Binding
Factors/chemistry/genetics/*metabolism
Clocks/*physiology
Techniques
Proteins/genetics/physiology
Data
Biological
Sequence
Two-Hybrid
*Gene
Protein
Animals
Motifs
Mesoderm/*metabolism
Proteins/chemistry/genetics/metabolism
Mice
Transduction
Expression
Receptor;Notch1
Regulation;Developmental
Repressor
*Receptors;Cell
*Avian
Factors
Embryo
Basic
Acid
In
Hybridization
Helix-Loop-Helix
Transcription
Chick
*Helix-Loop-Helix
Surface
Proteins/metabolism
System
Proteins
Morphogenesis
Situ
*Signal
Somites/metabolism
Molecular
Alignment
Membrane
Amino
Mice;Knockout
RNA;Messenger/analysis/geneticsBindingFactors/chemistry/genetics/*metabolismClocks/*physiologyTechniquesProteins/genetics/physiologyDataBiologicalSequenceTwo-Hybrid*GeneProteinAnimalsMotifsMesoderm/*metabolismProteins/chemistry/genetics/metabolismMiceTransductionExpressionReceptor;Notch1Regulation;DevelopmentalRepressor*Receptors;Cell*AvianFactorsEmbryoBasicAcidInHybridizationHelix-Loop-HelixTranscriptionChick*Helix-Loop-HelixSurfaceProteins/metabolismSystemProteinsMorphogenesisSitu*SignalSomites/metabolismMolecularAlignmentMembraneAminoMice;Knockout
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1Identification of BOIP, a novel cDNA highly expressed during spermatogenesis that encodes a protein interacting with the orange domain of the hairy-related transcription factor HRT1/Hey1 in Xenopus and mouse
R. van Wayenbergh, V. Taelman, B. Pichon, A. Fischer, S. Kricha, M. Gessler, D. Christophe, and E. Bellefroid. Dev Dyn, 228 (4): 716--725 (2003)
12 years ago by @ebch
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Embryo;Nonmammalian
DNA;Complementary/*metabolism
Plasmids/metabolism
Techniques
Cycle
*Gene
Cells
Proteins/biosynthesis/genetics
Nuclear
Receptors;Notch
Structure;Tertiary
Mice
Library
Expression
Ribonucleases/metabolism
Xenopus
Factors
Hybridization
Homology;Amino
Humans
Helix-Loop-Helix
Proteins/*biosynthesis/*genetics
Transcription
Testis/metabolism
Situ
RNA/metabolism
Carrier
Spermatozoa/*metabolism
Membrane
*Spermatogenesis
Cell
Cloning;Molecular
Binding
Precipitin
RNA;Messenger/metabolism
Data
Sequence
Two-Hybrid
Conserved
Protein
Animals
Hela
Transduction
Regulation;Developmental
Proteins/*chemistry/metabolism
Basic
Acid
In
Immunohistochemistry
Male
Embryo;Mammalian/metabolism
Transfection
Proteins/metabolism
System
Tests
Luciferases/metabolism
Molecular
Gene
Amino
Signal
Embryo;NonmammalianDNA;Complementary/*metabolismPlasmids/metabolismTechniquesCycle*GeneCellsProteins/biosynthesis/geneticsNuclearReceptors;NotchStructure;TertiaryMiceLibraryExpressionRibonucleases/metabolismXenopusFactorsHybridizationHomology;AminoHumansHelix-Loop-HelixProteins/*biosynthesis/*geneticsTranscriptionTestis/metabolismSituRNA/metabolismCarrierSpermatozoa/*metabolismMembrane*SpermatogenesisCellCloning;MolecularBindingPrecipitinRNA;Messenger/metabolismDataSequenceTwo-HybridConservedProteinAnimalsHelaTransductionRegulation;DevelopmentalProteins/*chemistry/metabolismBasicAcidInImmunohistochemistryMaleEmbryo;Mammalian/metabolismTransfectionProteins/metabolismSystemTestsLuciferases/metabolismMolecularGeneAminoSignal
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1Comparative analysis of the human and mouse Hey1 promoter: Hey genes are new Notch target genes
M. Maier, and M. Gessler. Biochem Biophys Res Commun, 275 (2): 652--660 (2000)
12 years ago by @ebch
show all tags
Factors/*genetics
Data
Primers
Sequence
Regions
Base
Protein
Animals
Motifs
DNA
Mice
Receptor;Notch1
*Receptors;Cell
*Nuclear
(Genetics)
Acid
Recombination
Humans
Up-Regulation
*Promoter
Transcription
Sequence-Binding
J
Immunoglobulin
*Helix-Loop-Helix
Surface
Proteins/metabolism
Proteins
Homology;Nucleic
Molecular
DNA-Binding
Transcription;Genetic
Membrane
Signal
Factors/*geneticsDataPrimersSequenceRegionsBaseProteinAnimalsMotifsDNAMiceReceptor;Notch1*Receptors;Cell*Nuclear(Genetics)AcidRecombinationHumansUp-Regulation*PromoterTranscriptionSequence-BindingJImmunoglobulin*Helix-Loop-HelixSurfaceProteins/metabolismProteinsHomology;NucleicMolecularDNA-BindingTranscription;GeneticMembraneSignal
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1Defining targets for complement components C4b and C3b on the pathogenic neisseriae
L. Lewis, S. Ram, A. Prasad, S. Gulati, S. Getzlaff, A. Blom, U. Vogel, and P. Rice. Infection and Immunity, 76 (1): 339--350 (January 2008)PMID: 17984207.
14 years ago by @ag_vogel
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Bacterial
Porins,
Binding,
C4b,
C3b,
Complement
serum_resistance
Outer
Protein
Humans,
meningitidis,
Proteins,
Isoforms
Neisseria
Membrane
gonorrhoeae,
BacterialPorins,Binding,C4b,C3b,Complementserum_resistanceOuterProteinHumans,meningitidis,Proteins,IsoformsNeisseriaMembranegonorrhoeae,
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1Rapid sequence-based identification of gonococcal transmission clusters in a large metropolitan area
I. Martin, C. Ison, D. Aanensen, K. Fenton, and B. Spratt. The Journal of Infectious Diseases, 189 (8): 1497--1505 (April 2004)PMID: 15073688.
14 years ago by @jelias
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Serotyping,
Analysis,
B,
Cluster
Sequence
{DNA,}
Gonorrhea,
Protein
Variation,
Humans,
Polymerase
Sensitivity
London,
Male,
Reproducibility
Neisseria
Bacterial
Chain
Reaction,
Bacterial,
Results,
Female,
Genetic
Outer
Alleles,
Urban
Proteins,
Tests,
of
Membrane
Population
Microbial
{Transferrin-Binding}
gonorrhoeae,
Serotyping,Analysis,B,ClusterSequence{DNA,}Gonorrhea,ProteinVariation,Humans,PolymeraseSensitivityLondon,Male,ReproducibilityNeisseriaBacterialChainReaction,Bacterial,Results,Female,GeneticOuterAlleles,UrbanProteins,Tests,ofMembranePopulationMicrobial{Transferrin-Binding}gonorrhoeae,
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1Conserved outer membrane protein of Neisseria meningitidis involved in capsule expression
M. Frosch, D. Müller, K. Bousset, and A. Müller. Infection and Immunity, 60 (3): 798--803 (March 1992)PMID: 1371768.
14 years ago by @jelias
show all tags
Animals,
Bacterial
Epitopes,
Mice,
Acid
C,
{BALB}
Outer
Sequence
Data,
Base
Protein
Molecular
meningitidis,
Proteins,
Antibodies,
Neisseria
Membrane
Amino
Monoclonal,
Sequence,
Inbred
Conformation
Animals,BacterialEpitopes,Mice,AcidC,{BALB}OuterSequenceData,BaseProteinMolecularmeningitidis,Proteins,Antibodies,NeisseriaMembraneAminoMonoclonal,Sequence,InbredConformation
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1Improved immunogenicity of a H44/76 group B outer membrane vesicle vaccine with over-expressed genome-derived Neisserial antigen 1870
O. Koeberling, J. Welsch, and D. Granoff. Vaccine, 25 (10): 1912--20 (February 2007)PMID: 16677743.
14 years ago by @jelias
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Binding
Mice,
Meningococcal,
B,
Flow
Vaccines,
Protein
Humans,
meningitidis,
Neisseria
Serogroup
Meningitis,
Animals,
Bacterial
Bacterial,
Female,
C3b,
Assay,
Complement
Cytometry,
Outer
Meningococcal
{Enzyme-Linked}
Proteins,
Antibodies,
Viability,
Immunosorbent
Membrane
Microbial
Antigens,
BindingMice,Meningococcal,B,FlowVaccines,ProteinHumans,meningitidis,NeisseriaSerogroupMeningitis,Animals,BacterialBacterial,Female,C3b,Assay,ComplementCytometry,OuterMeningococcal{Enzyme-Linked}Proteins,Antibodies,Viability,ImmunosorbentMembraneMicrobialAntigens,
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1Breakdown of axonal synaptic vesicle precursor transport by microglial nitric oxide
M. Stagi, P. Dittrich, N. Frank, A. Iliev, P. Schwille, and H. Neumann. J Neurosci, 25 (2): 352-62 (January 2005)Stagi, Massimiliano Dittrich, Petra S Frank, Nadja Iliev, Asparouh I Schwille, Petra Neumann, Harald Research Support, Non-U.S. Gov't United States The Journal of neuroscience : the official journal of the Society for Neuroscience J Neurosci. 2005 Jan 12;25(2):352-62..
14 years ago by @pharmawuerz
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C57BL
Vesicles/*metabolism
Inflammation/metabolism
Nitric
Kinases/metabolism
Protein
Animals
Synaptotagmins
Mice
Fusion
Green
Synaptophysin/metabolism
Mitogen-Activated
Synaptic
JNK
I
Calcium-Binding
Hippocampus/cytology/metabolism
Oxide/*physiology
Proteins/metabolism
Tissue
Glycoproteins/metabolism
Nerve
Fluorescent
Membrane
Synaptotagmin
Cultured
Axonal
Recombinant
Microglia/*metabolism
Transport/*physiology
Cell
C57BLVesicles/*metabolismInflammation/metabolismNitricKinases/metabolismProteinAnimalsSynaptotagminsMiceFusionGreenSynaptophysin/metabolismMitogen-ActivatedSynapticJNKICalcium-BindingHippocampus/cytology/metabolismOxide/*physiologyProteins/metabolismTissueGlycoproteins/metabolismNerveFluorescentMembraneSynaptotagminCulturedAxonalRecombinantMicroglia/*metabolismTransport/*physiologyCell
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1Functional regulation of L-type calcium channels via protein kinase A-mediated phosphorylation of the beta(2) subunit
M. Bunemann, B. Gerhardstein, T. Gao, and M. Hosey. J Biol Chem, 274 (48): 33851-4 (November 1999)Bunemann, M Gerhardstein, B L Gao, T Hosey, M M HL23306/HL/NHLBI NIH HHS/United States T32-DK07169/DK/NIDDK NIH HHS/United States Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. United states The Journal of biological chemistry J Biol Chem. 1999 Nov 26;274(48):33851-4..
14 years ago by @pharmawuerz
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Rabbits
Patch-Clamp
Techniques
Phosphorylation/drug
Electric
Channels,
Rats
Protein
effects
Animals
Cyclic
Line,
Fusion
Potentials/drug
Compounds/pharmacology
Barium
Calcium
Humans
Serine/metabolism
L-Type/chemistry/genetics/*metabolism
Stimulation
Proteins/genetics/metabolism
Chlorides/pharmacology
Transformed
Kinases/*pharmacology
Membrane
Recombinant
AMP-Dependent
Cell
RabbitsPatch-ClampTechniquesPhosphorylation/drugElectricChannels,RatsProteineffectsAnimalsCyclicLine,FusionPotentials/drugCompounds/pharmacologyBariumCalciumHumansSerine/metabolismL-Type/chemistry/genetics/*metabolismStimulationProteins/genetics/metabolismChlorides/pharmacologyTransformedKinases/*pharmacologyMembraneRecombinantAMP-DependentCell
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1Receptor-specific desensitization with purified proteins. Kinase dependence and receptor specificity of beta-arrestin and arrestin in the beta 2-adrenergic receptor and rhodopsin systems
M. Lohse, S. Andexinger, J. Pitcher, S. Trukawinski, J. Codina, J. Faure, M. Caron, and R. Lefkowitz. J Biol Chem, 267 (12): 8558-64 (April 1992)Lohse, M J Andexinger, S Pitcher, J Trukawinski, S Codina, J Faure, J P Caron, M G Lefkowitz, R J DK 19318/DK/NIDDK NIH HHS/United States HL 16037/HL/NHLBI NIH HHS/United States Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. United states The Journal of biological chemistry J Biol Chem. 1992 Apr 25;267(12):8558-64..
14 years ago by @pharmawuerz
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*Arrestins
Cricetinae
Electrophoresis,
&
DNA/genetics
Gel
Protein
beta-Adrenergic
*Cyclic
1
Substrate
beta/*metabolism
Animals
Receptor
Blotting,
Kinase
Kinases/*metabolism
Liquid
Line
purification/*metabolism
Proteins/isolation
GTP
Phosphorylation
Polyacrylamide
Activation
Arrestin
Phosphohydrolases/metabolism
Adrenergic
Proteins/metabolism
Rhodopsin/*metabolism
Eye
beta-Antagonists/metabolism
Kinases
Western
Specificity
Membrane
G-Protein-Coupled
GTP-Binding
Enzyme
Chromatography,
Antigens/isolation
AMP-Dependent
Cell
*ArrestinsCricetinaeElectrophoresis,&DNA/geneticsGelProteinbeta-Adrenergic*Cyclic1Substratebeta/*metabolismAnimalsReceptorBlotting,KinaseKinases/*metabolismLiquidLinepurification/*metabolismProteins/isolationGTPPhosphorylationPolyacrylamideActivationArrestinPhosphohydrolases/metabolismAdrenergicProteins/metabolismRhodopsin/*metabolismEyebeta-Antagonists/metabolismKinasesWesternSpecificityMembraneG-Protein-CoupledGTP-BindingEnzymeChromatography,Antigens/isolationAMP-DependentCell
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1Phosducin, potential role in modulation of olfactory signaling
I. Boekhoff, K. Touhara, S. Danner, J. Inglese, M. Lohse, H. Breer, and R. Lefkowitz. J Biol Chem, 272 (7): 4606-12 (February 1997)Boekhoff, I Touhara, K Danner, S Inglese, J Lohse, M J Breer, H Lefkowitz, R J HL16037/HL/NHLBI NIH HHS/United States Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. United states The Journal of biological chemistry J Biol Chem. 1997 Feb 14;272(7):4606-12..
14 years ago by @pharmawuerz
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Olfactory
*Protein-Serine-Threonine
Mutagenesis,
Rats
Kinases/metabolism
Protein
3
Animals
Proteins/genetics/*metabolism
Receptor
Site-Directed
Cyclic
Kinase
Transduction
Pathways/*metabolism
AMP/metabolism
Regulators
Phosphorylation
Protein-Tyrosine
Humans
Proteins/metabolism
Eye
*Signal
Kinases
Phosphoproteins/genetics/*metabolism
Membrane
G-Protein-Coupled
GTP-Binding
Sprague-Dawley
Olfactory*Protein-Serine-ThreonineMutagenesis,RatsKinases/metabolismProtein3AnimalsProteins/genetics/*metabolismReceptorSite-DirectedCyclicKinaseTransductionPathways/*metabolismAMP/metabolismRegulatorsPhosphorylationProtein-TyrosineHumansProteins/metabolismEye*SignalKinasesPhosphoproteins/genetics/*metabolismMembraneG-Protein-CoupledGTP-BindingSprague-Dawley
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1C-terminal fragments of the alpha 1C (CaV1.2) subunit associate with and regulate L-type calcium channels containing C-terminal-truncated alpha 1C subunits
T. Gao, A. Cuadra, H. Ma, M. Bunemann, B. Gerhardstein, T. Cheng, R. Eick, and M. Hosey. J Biol Chem, 276 (24): 21089-97 (June 2001)Gao, T Cuadra, A E Ma, H Bunemann, M Gerhardstein, B L Cheng, T Eick, R T Hosey, M M HL23306/HL/NHLBI NIH HHS/United States T32-DK07169/DK/NIDDK NIH HHS/United States Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. United States The Journal of biological chemistry J Biol Chem. 2001 Jun 15;276(24):21089-97. Epub 2001 Mar 26..
14 years ago by @pharmawuerz
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Patch-Clamp
Barium/pharmacology
Techniques
Channels,
Sequence
Mammals
Fragments/chemistry/pharmacology
Protein
Animals
Line
Kinetics
effects/metabolism
L-Type/*chemistry/drug
effects/*physiology
Potentials/drug
Calcium
Humans
effects/physiology
Transfection
Membrane/physiology
Subunits
Membrane
Proteins/chemistry/drug
Deletion
Peptide
Recombinant
Cell
Patch-ClampBarium/pharmacologyTechniquesChannels,SequenceMammalsFragments/chemistry/pharmacologyProteinAnimalsLineKineticseffects/metabolismL-Type/*chemistry/drugeffects/*physiologyPotentials/drugCalciumHumanseffects/physiologyTransfectionMembrane/physiologySubunitsMembraneProteins/chemistry/drugDeletionPeptideRecombinantCell
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1Spatiotemporal dynamics of beta-adrenergic cAMP signals and L-type Ca2+ channel regulation in adult rat ventricular myocytes: role of phosphodiesterases
J. Leroy, A. Abi-Gerges, V. Nikolaev, W. Richter, P. Lechene, J. Mazet, M. Conti, R. Fischmeister, and G. Vandecasteele. Circ Res, 102 (9): 1091-100 (May 2008)Leroy, Jerome Abi-Gerges, Aniella Nikolaev, Viacheslav O Richter, Wito Lechene, Patrick Mazet, Jean-Luc Conti, Marco Fischmeister, Rodolphe Vandecasteele, Gregoire HD20788/HD/NICHD NIH HHS/United States Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't United States Circulation research Circ Res. 2008 May 9;102(9):1091-100. Epub 2008 Mar 27..
14 years ago by @pharmawuerz
show all tags
Techniques
Fluorescence/methods
Nucleotide
Rats
Biosensing
Wistar
Exchange
effects
*Myocardial
Potentials
AMP/*metabolism
Inhibitors/pharmacology
Kinetics
Transfer
Resonance
effects/*metabolism
Calcium
Activation
Phosphodiesterases,
Sarcolemma/metabolism
Dose-Response
L-Type/*metabolism
Membrane
Cultured
Relationship,
Energy
Cell
Phosphodiesterase
&
inhibitors/*metabolism
Contraction/drug
4/antagonists
Channels,
Transduction/drug
Ventricles/metabolism
Kinases/metabolism
Protein
Cation
Type
Cardiac/drug
Animals
Receptor
Nucleotide-Gated
Cyclic
3/antagonists
Quinolones/pharmacology
Microscopy,
beta/drug
beta-Agonists/pharmacology
Cytosol/metabolism
Isoproterenol/pharmacology
Factors/genetics/metabolism
Heart
Phosphorylation
Myocytes,
effects/enzymology/*metabolism
Male
Fluorescence
Transfection
Adrenergic
Guanine
*Signal
Channels/genetics/metabolism
Enzyme
AMP-Dependent
4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone/pharmacology
Drug
TechniquesFluorescence/methodsNucleotideRatsBiosensingWistarExchangeeffects*MyocardialPotentialsAMP/*metabolismInhibitors/pharmacologyKineticsTransferResonanceeffects/*metabolismCalciumActivationPhosphodiesterases,Sarcolemma/metabolismDose-ResponseL-Type/*metabolismMembraneCulturedRelationship,EnergyCellPhosphodiesterase&inhibitors/*metabolismContraction/drug4/antagonistsChannels,Transduction/drugVentricles/metabolismKinases/metabolismProteinCationTypeCardiac/drugAnimalsReceptorNucleotide-GatedCyclic3/antagonistsQuinolones/pharmacologyMicroscopy,beta/drugbeta-Agonists/pharmacologyCytosol/metabolismIsoproterenol/pharmacologyFactors/genetics/metabolismHeartPhosphorylationMyocytes,effects/enzymology/*metabolismMaleFluorescenceTransfectionAdrenergicGuanine*SignalChannels/genetics/metabolismEnzymeAMP-Dependent4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone/pharmacologyDrug
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1Regulators of G-protein-mediated signalling
M. Lohse, K. Bluml, S. Danner, and C. Krasel. Biochem Soc Trans, 24 (4): 975-80 (November 1996)Lohse, M J Bluml, K Danner, S Krasel, C Review England Biochemical Society transactions Biochem Soc Trans. 1996 Nov;24(4):975-80..
14 years ago by @pharmawuerz
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Caveolin
ADP-Ribosylation
Protein
1
Proteins/*physiology
Animals
Proteins/physiology
Receptor
*Caveolins
Factors
Regulators
Glycoproteins/physiology
Protein-Tyrosine
Phosphoproteins/physiology
Humans
Tissue
Eye
Nerve
GAP-43
Transduction/*physiology
Kinases/physiology
Membrane
GTP-Binding
Tubulin/physiology
Signal
CaveolinADP-RibosylationProtein1Proteins/*physiologyAnimalsProteins/physiologyReceptor*CaveolinsFactorsRegulatorsGlycoproteins/physiologyProtein-TyrosinePhosphoproteins/physiologyHumansTissueEyeNerveGAP-43Transduction/*physiologyKinases/physiologyMembraneGTP-BindingTubulin/physiologySignal
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1Comparative rates of desensitization of beta-adrenergic receptors by the beta-adrenergic receptor kinase and the cyclic AMP-dependent protein kinase
N. Roth, P. Campbell, M. Caron, R. Lefkowitz, and M. Lohse. Proc Natl Acad Sci U S A, 88 (14): 6201-4 (July 1991)Roth, N S Campbell, P T Caron, M G Lefkowitz, R J Lohse, M J HL16037/HL/NHLBI NIH HHS/United States Comparative Study Research Support, U.S. Gov't, P.H.S. United states Proceedings of the National Academy of Sciences of the United States of America Proc Natl Acad Sci U S A. 1991 Jul 15;88(14):6201-4..
14 years ago by @pharmawuerz
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Isoproterenol/*pharmacology
Humans
Permeability
A/pharmacology
Adrenergic
Concanavalin
Proteins/metabolism
Protein
beta-Adrenergic
*Cyclic
Receptor
Kinases
Kinases/*metabolism
Line
Carcinoma,
Membrane
Kinetics
GTP-Binding
beta/drug
effects/*metabolism
Squamous
AMP-Dependent
Cell
Isoproterenol/*pharmacologyHumansPermeabilityA/pharmacologyAdrenergicConcanavalinProteins/metabolismProteinbeta-Adrenergic*CyclicReceptorKinasesKinases/*metabolismLineCarcinoma,MembraneKineticsGTP-Bindingbeta/drugeffects/*metabolismSquamousAMP-DependentCell
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1Common genomic response in different mouse models of beta-adrenergic-induced cardiomyopathy
V. Gaussin, J. Tomlinson, C. Depre, S. Engelhardt, C. Antos, G. Takagi, L. Hein, J. Topper, S. Liggett, E. Olson and 3 other author(s). Circulation, 108 (23): 2926-33 (December 2003)Gaussin, Vinciane Tomlinson, James E Depre, Christophe Engelhardt, Stefan Antos, Christopher L Takagi, Gen Hein, Lutz Topper, James N Liggett, Stephen B Olson, Eric N Lohse, Martin J Vatner, Stephen F Vatner, Dorothy E AG14121/AG/NIA NIH HHS/United States HL33107/HL/NHLBI NIH HHS/United States HL59139/HL/NHLBI NIH HHS/United States HL69020/HL/NHLBI NIH HHS/United States Comparative Study Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. United States Circulation Circulation. 2003 Dec 9;108(23):2926-33. Epub 2003 Nov 17..
14 years ago by @pharmawuerz
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1Mutation of Asn293 to Asp in transmembrane helix VI abolishes agonist-induced but not constitutive activity of the beta(2)-adrenergic receptor
A. Hannawacker, C. Krasel, and M. Lohse. Mol Pharmacol, 62 (6): 1431-7 (December 2002)Hannawacker, Annette Krasel, Cornelius Lohse, Martin J Research Support, Non-U.S. Gov't United States Molecular pharmacology Mol Pharmacol. 2002 Dec;62(6):1431-7..
14 years ago by @pharmawuerz
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1Mitochondrial Protein Translocation-Associated Degradation.

1Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans

1Cloning and expression analysis of the mouse stroma marker Snep encoding a novel nidogen domain protein

1Oscillating expression of c-Hey2 in the presomitic mesoderm suggests that the segmentation clock may use combinatorial signaling through multiple interacting bHLH factors

1Identification of BOIP, a novel cDNA highly expressed during spermatogenesis that encodes a protein interacting with the orange domain of the hairy-related transcription factor HRT1/Hey1 in Xenopus and mouse

1Comparative analysis of the human and mouse Hey1 promoter: Hey genes are new Notch target genes

1Defining targets for complement components C4b and C3b on the pathogenic neisseriae

1Rapid sequence-based identification of gonococcal transmission clusters in a large metropolitan area

1Conserved outer membrane protein of Neisseria meningitidis involved in capsule expression

1Improved immunogenicity of a H44/76 group B outer membrane vesicle vaccine with over-expressed genome-derived Neisserial antigen 1870

1Breakdown of axonal synaptic vesicle precursor transport by microglial nitric oxide

1Functional regulation of L-type calcium channels via protein kinase A-mediated phosphorylation of the beta(2) subunit

1Receptor-specific desensitization with purified proteins. Kinase dependence and receptor specificity of beta-arrestin and arrestin in the beta 2-adrenergic receptor and rhodopsin systems

1Phosducin, potential role in modulation of olfactory signaling

1C-terminal fragments of the alpha 1C (CaV1.2) subunit associate with and regulate L-type calcium channels containing C-terminal-truncated alpha 1C subunits

1Spatiotemporal dynamics of beta-adrenergic cAMP signals and L-type Ca2+ channel regulation in adult rat ventricular myocytes: role of phosphodiesterases

1Regulators of G-protein-mediated signalling

1Comparative rates of desensitization of beta-adrenergic receptors by the beta-adrenergic receptor kinase and the cyclic AMP-dependent protein kinase

1Common genomic response in different mouse models of beta-adrenergic-induced cardiomyopathy

1Mutation of Asn293 to Asp in transmembrane helix VI abolishes agonist-induced but not constitutive activity of the beta(2)-adrenergic receptor

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