M. > Protein Patch-Clamp

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1G Protein activation without subunit dissociation depends on a Galpha(i)-specific region
M. Frank, L. Thumer, M. Lohse, und M. Bunemann. J Biol Chem, 280 (26): 24584-90 (Juli 2005)Frank, Monika Thumer, Leonore Lohse, Martin J Bunemann, Moritz United States The Journal of biological chemistry J Biol Chem. 2005 Jul 1;280(26):24584-90. Epub 2005 May 2..
vor 14 Jahren von @pharmawuerz
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Luminescent
Binding
Patch-Clamp
Structure,
Gi-Go/*chemistry/metabolism
Techniques
Tertiary
Data
Mutagenesis,
Sequence
Rats
Protein
Animals
Proteins/chemistry
Site-Directed
DNA,
Transfer
Resonance
Transduction
Fusion
Green
Bacterial
Factors
Acid
Electrophysiology
Fluorescence
Time
Proteins/metabolism
Molecular
alpha
Homology,
Fluorescent
GTP-Binding
Amino
Energy
Dimerization
Complementary/metabolism
Recombinant
Signal
Buffers
Proteins/*chemistry
Subunits,
LuminescentBindingPatch-ClampStructure,Gi-Go/*chemistry/metabolismTechniquesTertiaryDataMutagenesis,SequenceRatsProteinAnimalsProteins/chemistrySite-DirectedDNA,TransferResonanceTransductionFusionGreenBacterialFactorsAcidElectrophysiologyFluorescenceTimeProteins/metabolismMolecularalphaHomology,FluorescentGTP-BindingAminoEnergyDimerizationComplementary/metabolismRecombinantSignalBuffersProteins/*chemistrySubunits,
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1Functional regulation of L-type calcium channels via protein kinase A-mediated phosphorylation of the beta(2) subunit
M. Bunemann, B. Gerhardstein, T. Gao, und M. Hosey. J Biol Chem, 274 (48): 33851-4 (November 1999)Bunemann, M Gerhardstein, B L Gao, T Hosey, M M HL23306/HL/NHLBI NIH HHS/United States T32-DK07169/DK/NIDDK NIH HHS/United States Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. United states The Journal of biological chemistry J Biol Chem. 1999 Nov 26;274(48):33851-4..
vor 14 Jahren von @pharmawuerz
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Rabbits
Patch-Clamp
Techniques
Phosphorylation/drug
Electric
Channels,
Rats
Protein
effects
Animals
Cyclic
Line,
Fusion
Potentials/drug
Compounds/pharmacology
Barium
Calcium
Humans
Serine/metabolism
L-Type/chemistry/genetics/*metabolism
Stimulation
Proteins/genetics/metabolism
Chlorides/pharmacology
Transformed
Kinases/*pharmacology
Membrane
Recombinant
AMP-Dependent
Cell
RabbitsPatch-ClampTechniquesPhosphorylation/drugElectricChannels,RatsProteineffectsAnimalsCyclicLine,FusionPotentials/drugCompounds/pharmacologyBariumCalciumHumansSerine/metabolismL-Type/chemistry/genetics/*metabolismStimulationProteins/genetics/metabolismChlorides/pharmacologyTransformedKinases/*pharmacologyMembraneRecombinantAMP-DependentCell
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1Role of the C terminus of the alpha 1C (CaV1.2) subunit in membrane targeting of cardiac L-type calcium channels
T. Gao, M. Bunemann, B. Gerhardstein, H. Ma, und M. Hosey. J Biol Chem, 275 (33): 25436-44 (August 2000)Gao, T Bunemann, M Gerhardstein, B L Ma, H Hosey, M M HL 23306/HL/NHLBI NIH HHS/United States Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. United states The Journal of biological chemistry J Biol Chem. 2000 Aug 18;275(33):25436-44..
vor 14 Jahren von @pharmawuerz
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Binding
Patch-Clamp
Structure,
Antibody
Precipitin
Technique
Techniques
Tertiary
Channels,
Mutagenesis,
Membrane/metabolism
Protein
Site-Directed
Line
Ligands
Calcium
Humans
Immunoblotting
Transfection
Tests
Gene
Fluorescent
Deletion
L-Type/*chemistry/metabolism/physiology
Cell
Proline/chemistry
BindingPatch-ClampStructure,AntibodyPrecipitinTechniqueTechniquesTertiaryChannels,Mutagenesis,Membrane/metabolismProteinSite-DirectedLineLigandsCalciumHumansImmunoblottingTransfectionTestsGeneFluorescentDeletionL-Type/*chemistry/metabolism/physiologyCellProline/chemistry
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1C-terminal fragments of the alpha 1C (CaV1.2) subunit associate with and regulate L-type calcium channels containing C-terminal-truncated alpha 1C subunits
T. Gao, A. Cuadra, H. Ma, M. Bunemann, B. Gerhardstein, T. Cheng, R. Eick, und M. Hosey. J Biol Chem, 276 (24): 21089-97 (Juni 2001)Gao, T Cuadra, A E Ma, H Bunemann, M Gerhardstein, B L Cheng, T Eick, R T Hosey, M M HL23306/HL/NHLBI NIH HHS/United States T32-DK07169/DK/NIDDK NIH HHS/United States Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. United States The Journal of biological chemistry J Biol Chem. 2001 Jun 15;276(24):21089-97. Epub 2001 Mar 26..
vor 14 Jahren von @pharmawuerz
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Patch-Clamp
Barium/pharmacology
Techniques
Channels,
Sequence
Mammals
Fragments/chemistry/pharmacology
Protein
Animals
Line
Kinetics
effects/metabolism
L-Type/*chemistry/drug
effects/*physiology
Potentials/drug
Calcium
Humans
effects/physiology
Transfection
Membrane/physiology
Subunits
Membrane
Proteins/chemistry/drug
Deletion
Peptide
Recombinant
Cell
Patch-ClampBarium/pharmacologyTechniquesChannels,SequenceMammalsFragments/chemistry/pharmacologyProteinAnimalsLineKineticseffects/metabolismL-Type/*chemistry/drugeffects/*physiologyPotentials/drugCalciumHumanseffects/physiologyTransfectionMembrane/physiologySubunitsMembraneProteins/chemistry/drugDeletionPeptideRecombinantCell
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1Potentiation of fractional sarcoplasmic reticulum calcium release by total and free intra-sarcoplasmic reticulum calcium concentration.
T. Shannon, K. Ginsburg, und D. Bers. Biophys. J., 78 (1): 334--343 (Januar 2000)
vor 16 Jahren von @hake
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Ruthenium
Mice,
{C}a$^{2+}$-Transporting
Calcium,
Failure,
Ion
beta-Agonists,
Biological,
Electric
Simulation,
Transport,
Humans,
Stimulation,
Kinases,
Intracellular
Techniques,
Caffeine,
Thermodynamics,
Membrane,
10620297
Ventricles,
Animals,
Calcium
Dogs,
Calcium-Binding
Regulation,
Research
Time
Cells,
Fibers,
Factors,
Allosteric
U.S.
Membrane
Tetracaine,
Muscle
Cell
Patch-Clamp
Membranes,
Cytosol,
Channels,
Biological
Mutagenesis,
Catalytic
Contraction,
Potentials,
Support,
Sodium-Calcium
Congestive,
Protein
Reticulum,
P.H.S.,
Cyclic
Isoproterenol,
ATPase,
Microsomes,
Domain,
Knockout,
Nickel,
Activation,
Models,
Exchanger,
Rabbits,
Red,
Adenosine
Ferrets,
Signaling,
Action
Heart
Hydrolysis,
Myocytes,
Binding,
Myocardium,
Cardiovascular,
Sarcoplasmic
Gov't,
Adrenergic
Triphosphate,
Kinetics,
Proteins,
Thapsigargin,
Cardiac,
Non-U.S.
Inhibitors,
Myocardial
Computer
Diastole,
Phosphorylation,
Enzyme
AMP-Dependent
Cultured,
Heart,
RutheniumMice,{C}a$^{2+}$-TransportingCalcium,Failure,Ionbeta-Agonists,Biological,ElectricSimulation,Transport,Humans,Stimulation,Kinases,IntracellularTechniques,Caffeine,Thermodynamics,Membrane,10620297Ventricles,Animals,CalciumDogs,Calcium-BindingRegulation,ResearchTimeCells,Fibers,Factors,AllostericU.S.MembraneTetracaine,MuscleCellPatch-ClampMembranes,Cytosol,Channels,BiologicalMutagenesis,CatalyticContraction,Potentials,Support,Sodium-CalciumCongestive,ProteinReticulum,P.H.S.,CyclicIsoproterenol,ATPase,Microsomes,Domain,Knockout,Nickel,Activation,Models,Exchanger,Rabbits,Red,AdenosineFerrets,Signaling,ActionHeartHydrolysis,Myocytes,Binding,Myocardium,Cardiovascular,SarcoplasmicGov't,AdrenergicTriphosphate,Kinetics,Proteins,Thapsigargin,Cardiac,Non-U.S.Inhibitors,MyocardialComputerDiastole,Phosphorylation,EnzymeAMP-DependentCultured,Heart,
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1Four kinetically distinct depolarization-activated K$^+$ currents in adult mouse ventricular myocytes.
H. Xu, W. Guo, und J. Nerbonne. J. Gen. Physiol., 113 (5): 661--678 (Mai 1999)
vor 16 Jahren von @hake
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Luminescent
10228181
Mice,
Electric
Humans,
Techniques,
Inbred
Ventricles,
Green
Animals,
Transfection,
C57BL,
Research
Time
Cells,
Electrophysiology,
Fibers,
Factors,
Vitro,
Dominant,
U.S.
Up-Regulation,
Fluorescent
Algorithms,
Membrane
Indicators
Muscle
Cell
Patch-Clamp
Voltage-Gated,
Genes,
Transgenic,
Channels,
Potentials,
Support,
Reagents,
Protein
P.H.S.,
Blotting,
Post-Translational,
Line,
Knockout,
Kidney,
Potassium
Action
Heart
In
Myocardium,
Gov't,
Comparative
Potassium,
Western,
Expression,
Kinetics,
Proteins,
Gene
Non-U.S.
and
Study,
Electrocardiography,
Processing,
Cultured,
Isoforms,
Conductivity,
Luminescent10228181Mice,ElectricHumans,Techniques,InbredVentricles,GreenAnimals,Transfection,C57BL,ResearchTimeCells,Electrophysiology,Fibers,Factors,Vitro,Dominant,U.S.Up-Regulation,FluorescentAlgorithms,MembraneIndicatorsMuscleCellPatch-ClampVoltage-Gated,Genes,Transgenic,Channels,Potentials,Support,Reagents,ProteinP.H.S.,Blotting,Post-Translational,Line,Knockout,Kidney,PotassiumActionHeartInMyocardium,Gov't,ComparativePotassium,Western,Expression,Kinetics,Proteins,GeneNon-U.S.andStudy,Electrocardiography,Processing,Cultured,Isoforms,Conductivity,
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1Reverse mode of the sarcoplasmic reticulum calcium pump and load-dependent cytosolic calcium decline in voltage-clamped cardiac ventricular myocytes.
T. Shannon, K. Ginsburg, und D. Bers. Biophys. J., 78 (1): 322--333 (Januar 2000)
vor 16 Jahren von @hake
alle anzeigen
Ruthenium
Mice,
{C}a$^{2+}$-Transporting
Calcium,
Failure,
Ion
beta-Agonists,
Biological,
Electric
Simulation,
Transport,
Humans,
Stimulation,
Kinases,
Troponin,
Intracellular
Techniques,
Caffeine,
Thermodynamics,
10620296
Membrane,
Ventricles,
Animals,
Calcium
Dogs,
Calcium-Binding
Regulation,
Research
Time
Cells,
Fibers,
Factors,
Allosteric
U.S.
Membrane
Tetracaine,
Muscle
lular
Cell
Patch-Clamp
Membranes,
Cytosol,
Channels,
Biological
Mutagenesis,
Catalytic
Contraction,
Potentials,
Support,
Sodium-Calcium
Congestive,
Protein
Reticulum,
P.H.S.,
Cyclic
Isoproterenol,
ATPase,
Microsomes,
Domain,
Knockout,
Nickel,
Activation,
Intracel,
Models,
Exchanger,
Rabbits,
Red,
Adenosine
Ferrets,
Signaling,
Action
Heart
Hydrolysis,
Myocytes,
Binding,
Myocardium,
Cardiovascular,
Sarcoplasmic
Gov't,
Adrenergic
Triphosphate,
Kinetics,
Proteins,
Thapsigargin,
Cardiac,
Non-U.S.
Inhibitors,
Myocardial
Computer
Diastole,
Phosphorylation,
Enzyme
AMP-Dependent
Cultured,
Heart,
RutheniumMice,{C}a$^{2+}$-TransportingCalcium,Failure,Ionbeta-Agonists,Biological,ElectricSimulation,Transport,Humans,Stimulation,Kinases,Troponin,IntracellularTechniques,Caffeine,Thermodynamics,10620296Membrane,Ventricles,Animals,CalciumDogs,Calcium-BindingRegulation,ResearchTimeCells,Fibers,Factors,AllostericU.S.MembraneTetracaine,MusclelularCellPatch-ClampMembranes,Cytosol,Channels,BiologicalMutagenesis,CatalyticContraction,Potentials,Support,Sodium-CalciumCongestive,ProteinReticulum,P.H.S.,CyclicIsoproterenol,ATPase,Microsomes,Domain,Knockout,Nickel,Activation,Intracel,Models,Exchanger,Rabbits,Red,AdenosineFerrets,Signaling,ActionHeartHydrolysis,Myocytes,Binding,Myocardium,Cardiovascular,SarcoplasmicGov't,AdrenergicTriphosphate,Kinetics,Proteins,Thapsigargin,Cardiac,Non-U.S.Inhibitors,MyocardialComputerDiastole,Phosphorylation,EnzymeAMP-DependentCultured,Heart,
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1Differential distribution and regulation of mouse cardiac Na$^+$/K$^+$-ATPase alpha1 and alpha2 subunits in T-tubule and surface sarcolemmal membranes.
R. Berry, S. Despa, W. Fuller, D. Bers, und M. Shattock. Cardiovasc. Res., 73 (1): 92--100 (Januar 2007)
vor 16 Jahren von @hake
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Ventricles;
Patch-Clamp
Mice,
beta-Agonists,
Techniques;
analysis/metabolism
Formamides;
metabolism;
Protein
enzymology;
Mice;
C57BL;
Sodium,
Kinases,
Cyclic
Isoproterenol,
analysis/metabolism;
pharmacology;
ATPase,
Animals;
Microscopy,
Inbred
Heart
Myocytes,
Confocal;
Adrenergic
Isoenzymes,
Fibers,
Cardiac,
Sarcolemma,
Muscle
Sodium-Potassium-Exchanging
enzymology/ultrastructure;
AMP-Dependent
Ventricles;Patch-ClampMice,beta-Agonists,Techniques;analysis/metabolismFormamides;metabolism;Proteinenzymology;Mice;C57BL;Sodium,Kinases,CyclicIsoproterenol,analysis/metabolism;pharmacology;ATPase,Animals;Microscopy,InbredHeartMyocytes,Confocal;AdrenergicIsoenzymes,Fibers,Cardiac,Sarcolemma,MuscleSodium-Potassium-Exchangingenzymology/ultrastructure;AMP-Dependent
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1Calcium fluxes involved in control of cardiac myocyte contraction.
D. Bers. Circ. Res., 87 (4): 275--281 (August 2000)
vor 16 Jahren von @hake
alle anzeigen
Ruthenium
Mice,
{C}a$^{2+}$-Transporting
Calcium,
Electric
Transport,
Humans,
Stimulation,
Kinases,
Intracellular
Techniques,
Caffeine,
Thermodynamics,
Ventricles,
Animals,
Calcium
Cold,
Calcium-Binding
Research
Time
Chlorides,
Electrophysiology,
Fibers,
Factors,
10948060
U.S.
Membrane
Muscle
Temperature,
Patch-Clamp
Membranes,
Channels,
Sprague-Dawley,
Biological
Catalytic
Contraction,
Potentials,
Support,
Acid,
Rats,
Protein
Reticulum,
P.H.S.,
Cations,
Sodium,
Cyclic
ATPase,
Microsomes,
Domain,
Knockout,
Activation,
Rabbits,
Red,
Adenosine
Action
Heart
Hydrolysis,
Binding,
Myocardium,
Sarcoplasmic
Gov't,
Comparative
Triphosphate,
Kinetics,
Niflumic
Proteins,
Thapsigargin,
Non-U.S.
Inhibitors,
Myocardial
Study,
Phosphorylation,
Enzyme
AMP-Dependent
RutheniumMice,{C}a$^{2+}$-TransportingCalcium,ElectricTransport,Humans,Stimulation,Kinases,IntracellularTechniques,Caffeine,Thermodynamics,Ventricles,Animals,CalciumCold,Calcium-BindingResearchTimeChlorides,Electrophysiology,Fibers,Factors,10948060U.S.MembraneMuscleTemperature,Patch-ClampMembranes,Channels,Sprague-Dawley,BiologicalCatalyticContraction,Potentials,Support,Acid,Rats,ProteinReticulum,P.H.S.,Cations,Sodium,CyclicATPase,Microsomes,Domain,Knockout,Activation,Rabbits,Red,AdenosineActionHeartHydrolysis,Binding,Myocardium,SarcoplasmicGov't,ComparativeTriphosphate,Kinetics,NiflumicProteins,Thapsigargin,Non-U.S.Inhibitors,MyocardialStudy,Phosphorylation,EnzymeAMP-Dependent
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Publikationen (verstecken)9
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1G Protein activation without subunit dissociation depends on a Galpha(i)-specific region

1Functional regulation of L-type calcium channels via protein kinase A-mediated phosphorylation of the beta(2) subunit

1Role of the C terminus of the alpha 1C (CaV1.2) subunit in membrane targeting of cardiac L-type calcium channels

1C-terminal fragments of the alpha 1C (CaV1.2) subunit associate with and regulate L-type calcium channels containing C-terminal-truncated alpha 1C subunits

1Potentiation of fractional sarcoplasmic reticulum calcium release by total and free intra-sarcoplasmic reticulum calcium concentration.

1Four kinetically distinct depolarization-activated K$^+$ currents in adult mouse ventricular myocytes.

1Reverse mode of the sarcoplasmic reticulum calcium pump and load-dependent cytosolic calcium decline in voltage-clamped cardiac ventricular myocytes.

1Differential distribution and regulation of mouse cardiac Na$^+$/K$^+$-ATPase alpha1 and alpha2 subunits in T-tubule and surface sarcolemmal membranes.

1Calcium fluxes involved in control of cardiac myocyte contraction.

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Publikationen (verstecken)9 Anzeigeallesnur PublikationenPublikationen pro Seite5102050100 sortieren nachhinzugefügt amTitelAutorErscheinungsdatumEintragstypHilfe für erweiterte Sortierung... RSSBibTeXRDFmehr...

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