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1A new synthesis of sulfonamides by aminolysis of p-nitrophenylsulfonates yielding potent and selective adenosine A2B receptor antagonists
L. Yan, D. Bertarelli, A. Hayallah, H. Meyer, K. Klotz, and C. Muller. J Med Chem, 49 (14): 4384-91 (July 2006)Yan, Luo Bertarelli, Daniela C G Hayallah, Alaa M Meyer, Heiko Klotz, Karl-Norbert Muller, Christa E In Vitro Research Support, Non-U.S. Gov't United States Journal of medicinal chemistry J Med Chem. 2006 Jul 13;49(14):4384-91..
14 years ago by @pharmawuerz
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inhibitors
Cricetinae
Cricetulus
&
Humans
Radioligand
Proteins/antagonists
CHO
Rats
Arylsulfonates/*chemistry
Sulfonamides/*chemical
Assay
Animals
Receptor
A2B/*antagonists
Relationship
synthesis/chemistry/pharmacology
Structure-Activity
Brain/metabolism
Recombinant
Adenosine
Xanthines/*chemical
Cell
inhibitorsCricetinaeCricetulus&HumansRadioligandProteins/antagonistsCHORatsArylsulfonates/*chemistrySulfonamides/*chemicalAssayAnimalsReceptorA2B/*antagonistsRelationshipsynthesis/chemistry/pharmacologyStructure-ActivityBrain/metabolismRecombinantAdenosineXanthines/*chemicalCell
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