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1Structural, vibrational and electrochemical analysis and antibiotic activity study of chalcone (2E)-1-(3 `,-methoxy-4 `,-hydroxyphenyl)-3-(3-nitrophenyl)prop-2-en-1-one
T. Garcia, T. de Freitas, H. dos Santos, P. Bandeira, M. Juliao, J. Rocha, C. Nogueira, R. Pereira, A. Barreto, P. Freire and 2 other author(s). JOURNAL OF MOLECULAR STRUCTURE, (2020)
2 years ago by @ppgfis_ufc_br
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UV-Vis;
Cyclic
{Chalcone;
Antibacterial
Vibrational
voltammetry;
spectroscopy;
activity}
UV-Vis;Cyclic{Chalcone;AntibacterialVibrationalvoltammetry;spectroscopy;activity}
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1Synthesis, characterization, and SAMs electroactivity of ruthenium complexes with sulfur containing ligands
J. de Sousa, I. Diogenes, M. Temperini, F. Sales, S. de Pinheiro, R. Filho, J. de Andrade Junior, and I. de Moreira. JOURNAL OF ORGANOMETALLIC CHEMISTRY, 692 (17): 3691-3699 (2007)
2 years ago by @ppgfis_ufc_br
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cytochrome
ruthenium
simulation;
complexes;
containing
c}
{sulfur
voltammetry;
computational
SAM;
ligands;
cyclic
cytochromerutheniumsimulation;complexes;containingc}{sulfurvoltammetry;computationalSAM;ligands;cyclic
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1On the Mechanism of Co2 Electro-Cycloaddition to Propylene Oxides
S. Gallardo-Fuentes, R. Contreras, M. Isaacs, J. Honores, D. Quezada, E. Landaeta, and R. Ormazabal-Toledo. Journal of Co2 Utilization, (2016)
5 years ago by @dqcauchile
show all tags
reaction
efficient
capture
density
calculations,
system,
synthesis,
complexes,
electrochemical
dqcauchile
catalyst
dioxide,
liquids,
reduction,
cyclic
functional
electro-cycloaddition,
salen
co2
recovery,
conversion,
co2,
atmospheric
mechanism,
high-capacity,
ionic
carbonate
reactionefficientcapturedensitycalculations,system,synthesis,complexes,electrochemicaldqcauchilecatalystdioxide,liquids,reduction,cyclicfunctionalelectro-cycloaddition,salenco2recovery,conversion,co2,atmosphericmechanism,high-capacity,ioniccarbonate
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1Experimental and Theoretical Reduction Potentials of Some Biologically Active Ortho-Carbonyl Para-Quinones
M. Martinez-Cifuentes, R. Salazar, O. Ramirez-Rodriguez, B. Weiss-Lopez, and R. Araya-Maturana. Molecules, (2017)
5 years ago by @dqcauchile
show all tags
models,
electrochemistry,
functional
batteries
solvation
quinones,
botrytis-cinerea,
density-functional
p-benzoquinone,
ion
theory,
density
redox
aprotic-solvents,
dqcauchile
semiquinone,
aqueous-solution,
potential,
properties,
computational
electron-transfer,
voltammetry,
cyclic
models,electrochemistry,functionalbatteriessolvationquinones,botrytis-cinerea,density-functionalp-benzoquinone,iontheory,densityredoxaprotic-solvents,dqcauchilesemiquinone,aqueous-solution,potential,properties,computationalelectron-transfer,voltammetry,cyclic
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1Cyclometalated rhodium(III) complex with phen-dione ligand
G. Mansouri, A. Rezvani, H. Hadadzadeh, H. Khavasi, and H. Saravani. JOURNAL OF ORGANOMETALLIC CHEMISTRY, 692 (17): 3810-3815 (August 2007)
8 years ago by @hkhavasi
show all tags
cyclometalated
crystal
2-phenylpyridine;
1,10-phenanthroline-5,6-dione;
{Rh(III)
voltammetry}
structure;
complex;
cyclic
cyclometalatedcrystal2-phenylpyridine;1,10-phenanthroline-5,6-dione;{Rh(III)voltammetry}structure;complex;cyclic
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1Resistance of Adhesive Bonding of Ultra-High Performance Concrete to Hygrothermal, Corrosive, and Freeze-Thaw Cycling Environments
R. Krelaus, G. Wisner, S. Freisinger-Schadow, M. Schmidt, S. Böhm, and K. Dilger. Journal of ASTM International (JAI), 6 (9): 18 (2009)
11 years ago by @konker
show all tags
UHPC
Performance
climatic
accelerated
Ultra-High
freeze-thaw
bonding
testing
hygrothermal
adhesive
Concrete
aging
UHPFRC
cyclic
UHPCPerformanceclimaticacceleratedUltra-Highfreeze-thawbondingtestinghygrothermaladhesiveConcreteagingUHPFRCcyclic
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1Desensitization of the isolated beta 2-adrenergic receptor by beta-adrenergic receptor kinase, cAMP-dependent protein kinase, and protein kinase C occurs via distinct molecular mechanisms
J. Pitcher, M. Lohse, J. Codina, M. Caron, and R. Lefkowitz. Biochemistry, 31 (12): 3193-7 (March 1992)Pitcher, J Lohse, M J Codina, J Caron, M G Lefkowitz, R J HL16037/HL/NHLBI NIH HHS/United States Research Support, U.S. Gov't, P.H.S. United states Biochemistry Biochemistry. 1992 Mar 31;31(12):3193-7..
14 years ago by @pharmawuerz
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Cricetinae
beta-Agonists/*pharmacology
Lung/chemistry
&
Protein
beta-Adrenergic
*Cyclic
Animals
Proteins/physiology
Receptor
Cyclic
Kinase
Antigens/physiology
beta/*drug
Phosphorylation
Humans
AMP/physiology
Arrestin
Retina/chemistry
Synergism
Adrenergic
Eye
Kinases/*pharmacology
Kinases
C/*pharmacology
effects/isolation
purification
AMP-Dependent
Drug
Cricetinaebeta-Agonists/*pharmacologyLung/chemistry&Proteinbeta-Adrenergic*CyclicAnimalsProteins/physiologyReceptorCyclicKinaseAntigens/physiologybeta/*drugPhosphorylationHumansAMP/physiologyArrestinRetina/chemistrySynergismAdrenergicEyeKinases/*pharmacologyKinasesC/*pharmacologyeffects/isolationpurificationAMP-DependentDrug
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1Widespread receptivity to neuropeptide PDF throughout the neuronal circadian clock network of Drosophila revealed by real-time cyclic AMP imaging
O. Shafer, D. Kim, R. Dunbar-Yaffe, V. Nikolaev, M. Lohse, and P. Taghert. Neuron, 58 (2): 223-37 (April 2008)Shafer, Orie T Kim, Dong Jo Dunbar-Yaffe, Richard Nikolaev, Viacheslav O Lohse, Martin J Taghert, Paul H 2F32NS053222-02/NS/NINDS NIH HHS/United States MH067122/MH/NIMH NIH HHS/United States NS057105/NS/NINDS NIH HHS/United States NS21749/NS/NINDS NIH HHS/United States P30 NS057105-039005/NS/NINDS NIH HHS/United States R01 MH067122-04/MH/NIMH NIH HHS/United States R01 MH067122-05/MH/NIMH NIH HHS/United States R01 NS021749-21/NS/NINDS NIH HHS/United States Research Support, N.I.H., Extramural United States Neuron Neuron. 2008 Apr 24;58(2):223-37..
14 years ago by @pharmawuerz
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Luminescent
Motor
Forskolin/pharmacology
Neuropeptides/*metabolism/pharmacology
Drosophila
Regulation/drug
Systems
Proteins/genetics/*metabolism/pharmacology
Animal
Animals
Cyclic
AMP/*metabolism
Genetically
Neurons/drug
effects/*physiology
Expression
Hormones/genetics/metabolism
Circadian
Animals,
Behavior,
Modified
Diagnostic
Proteins/metabolism
Insect
Dose-Response
Brain/cytology
Gene
Imaging
Computer
Activity/genetics
Relationship,
Rhythm/*physiology
Drug
LuminescentMotorForskolin/pharmacologyNeuropeptides/*metabolism/pharmacologyDrosophilaRegulation/drugSystemsProteins/genetics/*metabolism/pharmacologyAnimalAnimalsCyclicAMP/*metabolismGeneticallyNeurons/drugeffects/*physiologyExpressionHormones/genetics/metabolismCircadianAnimals,Behavior,ModifiedDiagnosticProteins/metabolismInsectDose-ResponseBrain/cytologyGeneImagingComputerActivity/geneticsRelationship,Rhythm/*physiologyDrug
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1Synthetic peptides of the hamster beta 2-adrenoceptor as substrates and inhibitors of the beta-adrenoceptor kinase
J. Benovic, J. Onorato, M. Lohse, H. Dohlman, C. Staniszewski, M. Caron, and R. Lefkowitz. Br J Clin Pharmacol, (1990)Benovic, J L Onorato, J Lohse, M J Dohlman, H G Staniszewski, C Caron, M G Lefkowitz, R J England British journal of clinical pharmacology Br J Clin Pharmacol. 1990;30 Suppl 1:3S-12S..
14 years ago by @pharmawuerz
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synthesis/*metabolism/pharmacology
Cricetinae
Electrophoresis,
beta/*chemistry/metabolism
Data
Sequence
Gel
Peptides/chemical
Protein
beta-Adrenergic
Substrate
Animals
Inhibitors
Receptor
Cyclic
Kinase
Kinases/isolation
purification/*metabolism
Kinetics
Acid
Phosphorylation
Polyacrylamide
Adrenergic
Proteins/metabolism
Kinases
Molecular
Specificity
GTP-Binding
Amino
AMP-Dependent
synthesis/*metabolism/pharmacologyCricetinaeElectrophoresis,beta/*chemistry/metabolismDataSequenceGelPeptides/chemicalProteinbeta-AdrenergicSubstrateAnimalsInhibitorsReceptorCyclicKinaseKinases/isolationpurification/*metabolismKineticsAcidPhosphorylationPolyacrylamideAdrenergicProteins/metabolismKinasesMolecularSpecificityGTP-BindingAminoAMP-Dependent
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1Role of Rac 1 and cAMP in endothelial barrier stabilization and thrombin-induced barrier breakdown
Y. Baumer, V. Spindler, R. Werthmann, M. Bunemann, and J. Waschke. J Cell Physiol, 220 (3): 716-26 (September 2009)Baumer, Y Spindler, V Werthmann, R C Bunemann, M Waschke, J Research Support, Non-U.S. Gov't United States Journal of cellular physiology J Cell Physiol. 2009 Sep;220(3):716-26..
14 years ago by @pharmawuerz
show all tags
Techniques
Forskolin/pharmacology
effects/*enzymology
Cells/drug
inhibitors/*metabolism
Electric
rac1
Transduction/drug
Biosensing
effects
Cyclic
Gap
Inhibitors/pharmacology
Microscopy,
Transfer
Permeability/drug
Resonance
cdc42
Impedance
Factors
Junctions/drug
Humans
AMP/analogs
Thrombin/*metabolism
Fluorescence
Time
derivatives/*metabolism/pharmacology
*Signal
Pyrimidines/pharmacology
Cadherins/metabolism
Aminoquinolines/pharmacology
Protein/antagonists
Rolipram/pharmacology
Capillary
Calcium/metabolism
Endothelial
GTP-Binding
Cultured
Antigens,
Enzyme
Energy
Activators/pharmacology
CD/metabolism
Cell
Protein/metabolism
TechniquesForskolin/pharmacologyeffects/*enzymologyCells/druginhibitors/*metabolismElectricrac1Transduction/drugBiosensingeffectsCyclicGapInhibitors/pharmacologyMicroscopy,TransferPermeability/drugResonancecdc42ImpedanceFactorsJunctions/drugHumansAMP/analogsThrombin/*metabolismFluorescenceTimederivatives/*metabolism/pharmacology*SignalPyrimidines/pharmacologyCadherins/metabolismAminoquinolines/pharmacologyProtein/antagonistsRolipram/pharmacologyCapillaryCalcium/metabolismEndothelialGTP-BindingCulturedAntigens,EnzymeEnergyActivators/pharmacologyCD/metabolismCellProtein/metabolism
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1Pyrazolo4,3-e1,2,4-triazolo1,5-cpyrimidine derivatives as highly potent and selective human A(3) adenosine receptor antagonists: influence of the chain at the N(8) pyrazole nitrogen
P. Baraldi, B. Cacciari, R. Romagnoli, G. Spalluto, S. Moro, K. Klotz, E. Leung, K. Varani, S. Gessi, S. Merighi and 1 other author(s). J Med Chem, 43 (25): 4768-80 (December 2000)Baraldi, P G Cacciari, B Romagnoli, R Spalluto, G Moro, S Klotz, K N Leung, E Varani, K Gessi, S Merighi, S Borea, P A Research Support, Non-U.S. Gov't United states Journal of medicinal chemistry J Med Chem. 2000 Dec 14;43(25):4768-80..
14 years ago by @pharmawuerz
show all tags
inhibitors
Cricetinae
Humans
Radioligand
CHO
Pyrazoles/*chemistry
Purinergic
Assay
Animals
Receptor
Molecular
Cyclic
P1/*antagonists
Pyrimidines/*chemical
AMP/biosynthesis
Relationship
synthesis/chemistry/pharmacology
Models,
Structure-Activity
Adenosine
Structure
Cell
inhibitorsCricetinaeHumansRadioligandCHOPyrazoles/*chemistryPurinergicAssayAnimalsReceptorMolecularCyclicP1/*antagonistsPyrimidines/*chemicalAMP/biosynthesisRelationshipsynthesis/chemistry/pharmacologyModels,Structure-ActivityAdenosineStructureCell
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1Molecular events associated with the regulation of signaling by M2 muscarinic receptors
M. Hosey, R. Pals-Rylaarsdam, K. Lee, A. Roseberry, J. Benovic, V. Gurevich, and M. Bunemann. Life Sci, 64 (6-7): 363-8 (1999)Hosey, M M Pals-Rylaarsdam, R Lee, K B Roseberry, A G Benovic, J L Gurevich, V V Bunemann, M EY11500/EY/NEI NIH HHS/United States GM44944/GM/NIGMS NIH HHS/United States HL 50121/HL/NHLBI NIH HHS/United States etc. Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. England Life sciences Life Sci. 1999;64(6-7):363-8..
14 years ago by @pharmawuerz
show all tags
*GTPase-Activating
Dominant/genetics/physiology
Inwardly-Rectifying
effects
Toxin
Line
Down-Regulation/drug
M2
Humans
Adenylate
Bordetella/pharmacology
Channels
Factors,
Substitution
Muscarinic/genetics/*metabolism
Cell
*Potassium
Barium/pharmacology
&
Blockers
Proteins/antagonists
Channel
inhibitors/*metabolism
Genes,
Proteins/genetics/physiology
Channels,
Protein
beta-Adrenergic
Carbachol/pharmacology
Cyclase
Receptor
Cyclic
Transduction
Potassium
Acid
Phosphorylation
G
Virulence
*RGS
Arrestins/metabolism
Muscarinic
Transfection
Inwardly
Proteins
*Signal
Kinases
Protein-Coupled
Kinases/genetics/physiology
Rectifying
GTP-Binding
Channels/genetics/metabolism
Amino
AMP-Dependent
*GTPase-ActivatingDominant/genetics/physiologyInwardly-RectifyingeffectsToxinLineDown-Regulation/drugM2HumansAdenylateBordetella/pharmacologyChannelsFactors,SubstitutionMuscarinic/genetics/*metabolismCell*PotassiumBarium/pharmacology&BlockersProteins/antagonistsChannelinhibitors/*metabolismGenes,Proteins/genetics/physiologyChannels,Proteinbeta-AdrenergicCarbachol/pharmacologyCyclaseReceptorCyclicTransductionPotassiumAcidPhosphorylationGVirulence*RGSArrestins/metabolismMuscarinicTransfectionInwardlyProteins*SignalKinasesProtein-CoupledKinases/genetics/physiologyRectifyingGTP-BindingChannels/genetics/metabolismAminoAMP-Dependent
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1Phosphorylation of GRK2 by protein kinase C abolishes its inhibition by calmodulin
C. Krasel, S. Dammeier, R. Winstel, J. Brockmann, H. Mischak, and M. Lohse. J Biol Chem, 276 (3): 1911-5 (January 2001)Krasel, C Dammeier, S Winstel, R Brockmann, J Mischak, H Lohse, M J Research Support, Non-U.S. Gov't United States The Journal of biological chemistry J Biol Chem. 2001 Jan 19;276(3):1911-5. Epub 2000 Oct 19..
14 years ago by @pharmawuerz
show all tags
Isoenzymes/*metabolism
High
&
Mutagenesis,
Pressure
inhibitors/genetics/*metabolism
Protein
beta-Adrenergic
Substrate
2
Animals
Receptor
Site-Directed
Cyclic
Kinase
Liquid
Kinases/antagonists
Line
Mass
Phosphorylation
Humans
C/*metabolism
Serine/metabolism
Calmodulin/*metabolism
Kinases
Spectrometry
Specificity
G-Protein-Coupled
Chromatography,
AMP-Dependent
Cell
Isoenzymes/*metabolismHigh&Mutagenesis,Pressureinhibitors/genetics/*metabolismProteinbeta-AdrenergicSubstrate2AnimalsReceptorSite-DirectedCyclicKinaseLiquidKinases/antagonistsLineMassPhosphorylationHumansC/*metabolismSerine/metabolismCalmodulin/*metabolismKinasesSpectrometrySpecificityG-Protein-CoupledChromatography,AMP-DependentCell
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1Gq-mediated Ca2+ signals inhibit adenylyl cyclases 5/6 in vascular smooth muscle cells
K. von Hayn, R. Werthmann, V. Nikolaev, L. Hommers, M. Lohse, and M. Bunemann. Am J Physiol Cell Physiol, 298 (2): C324-32 (February 2010)von Hayn, Kathrin Werthmann, Ruth C Nikolaev, Viacheslav O Hommers, Leif G Lohse, Martin J Bunemann, Moritz Research Support, Non-U.S. Gov't United States American journal of physiology. Cell physiology Am J Physiol Cell Physiol. 2010 Feb;298(2):C324-32. Epub 2009 Nov 4..
14 years ago by @pharmawuerz
show all tags
Techniques
effects/*enzymology
Nucleotide
inhibitors/genetics/*metabolism
Biosensing
Muscle/drug
effects
inhibitors/metabolism
AMP/*metabolism
Cyclase/antagonists
Inhibitors/pharmacology
Uridine
Transfer
Mice
Resonance
Factors
RNA
Humans
Adenylate
Time
Phosphodiesterases,
Vascular/drug
Muscle,
Xanthines/pharmacology
Dose-Response
*Calcium
Cultured
Relationship,
Smooth
Energy
Cell
Phosphodiesterase
Vasoconstriction
Interference
&
Smooth,
Protein
1/antagonists
Type
Animals
Receptor
Cyclic
beta-Agonists/pharmacology
Isoenzymes/antagonists
Isoproterenol/pharmacology
Purinergic/metabolism
Myocytes,
Gq-G11/*metabolism
Fluorescence
Triphosphate/metabolism
Transfection
Adrenergic
Vasodilation
Aorta/enzymology
alpha
GTP-Binding
Signaling/drug
Subunits,
Drug
Techniqueseffects/*enzymologyNucleotideinhibitors/genetics/*metabolismBiosensingMuscle/drugeffectsinhibitors/metabolismAMP/*metabolismCyclase/antagonistsInhibitors/pharmacologyUridineTransferMiceResonanceFactorsRNAHumansAdenylateTimePhosphodiesterases,Vascular/drugMuscle,Xanthines/pharmacologyDose-Response*CalciumCulturedRelationship,SmoothEnergyCellPhosphodiesteraseVasoconstrictionInterference&Smooth,Protein1/antagonistsTypeAnimalsReceptorCyclicbeta-Agonists/pharmacologyIsoenzymes/antagonistsIsoproterenol/pharmacologyPurinergic/metabolismMyocytes,Gq-G11/*metabolismFluorescenceTriphosphate/metabolismTransfectionAdrenergicVasodilationAorta/enzymologyalphaGTP-BindingSignaling/drugSubunits,Drug
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1Two kinases mediate agonist-dependent phosphorylation and desensitization of the beta 2-adrenergic receptor
W. Hausdorff, M. Lohse, M. Bouvier, S. Liggett, M. Caron, and R. Lefkowitz. Symp Soc Exp Biol, (1990)Hausdorff, W P Lohse, M J Bouvier, M Liggett, S B Caron, M G Lefkowitz, R J 1F32GM13182/GM/NIGMS NIH HHS/United States HL02386/HL/NHLBI NIH HHS/United States HL16037/HL/NHLBI NIH HHS/United States Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. England Symposia of the Society for Experimental Biology Symp Soc Exp Biol. 1990;44:225-40..
14 years ago by @pharmawuerz
show all tags
Epinephrine/pharmacology
Mammals/*metabolism
Protein
beta-Adrenergic
*Cyclic
beta/genetics/*metabolism
Animals
beta-Agonists/*metabolism
Receptor
Cyclic
Kinases/*metabolism
Norepinephrine/pharmacology
Cyclase/metabolism
Phosphorylation
Humans
Down-Regulation/physiology
Cloning,
Adenylate
Adrenergic
Kinases
Molecular
AMP/biosynthesis
Cultured
AMP-Dependent
Cell
Epinephrine/pharmacologyMammals/*metabolismProteinbeta-Adrenergic*Cyclicbeta/genetics/*metabolismAnimalsbeta-Agonists/*metabolismReceptorCyclicKinases/*metabolismNorepinephrine/pharmacologyCyclase/metabolismPhosphorylationHumansDown-Regulation/physiologyCloning,AdenylateAdrenergicKinasesMolecularAMP/biosynthesisCulturedAMP-DependentCell
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1cAMP microdomains and L-type Ca2+ channel regulation in guinea-pig ventricular myocytes
S. Warrier, G. Ramamurthy, R. Eckert, V. Nikolaev, M. Lohse, and R. Harvey. J Physiol, 580 (Pt.3): 765-76 (May 2007)Warrier, Sunita Ramamurthy, Gopalakrishnan Eckert, Richard L Nikolaev, Viacheslav O Lohse, Martin J Harvey, Robert D Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't England The Journal of physiology J Physiol. 2007 May 1;580(Pt.3):765-76. Epub 2007 Feb 8..
14 years ago by @pharmawuerz
show all tags
Pigs
Structure,
Prostaglandin/metabolism
Tertiary
Channels,
Distribution/drug
Phosphoric
AMP/*physiology
Protein
effects
Animals
Receptor
Cyclic
Diester
Cardiac/*metabolism
effects/*metabolism
L-Type/drug
beta-Agonists/pharmacology
Cytosol/metabolism
Isoproterenol/pharmacology
Heart
Alprostadil/pharmacology
Calcium
Guinea
Myocytes,
Gi-Go/physiology
Adrenergic
Tissue
alpha
Hydrolases/metabolism
GTP-Binding
Cultured
Ventricles
Caveolae/metabolism
Cell
Subunits,
PigsStructure,Prostaglandin/metabolismTertiaryChannels,Distribution/drugPhosphoricAMP/*physiologyProteineffectsAnimalsReceptorCyclicDiesterCardiac/*metabolismeffects/*metabolismL-Type/drugbeta-Agonists/pharmacologyCytosol/metabolismIsoproterenol/pharmacologyHeartAlprostadil/pharmacologyCalciumGuineaMyocytes,Gi-Go/physiologyAdrenergicTissuealphaHydrolases/metabolismGTP-BindingCulturedVentriclesCaveolae/metabolismCellSubunits,
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1Pyrazolo4,3-e-1,2,4-triazolo1,5-cpyrimidine derivatives as highly potent and selective human A(3) adenosine receptor antagonists
P. Baraldi, B. Cacciari, R. Romagnoli, G. Spalluto, K. Klotz, E. Leung, K. Varani, S. Gessi, S. Merighi, and P. Borea. J Med Chem, 42 (22): 4473-8 (November 1999)Baraldi, P G Cacciari, B Romagnoli, R Spalluto, G Klotz, K N Leung, E Varani, K Gessi, S Merighi, S Borea, P A In Vitro Research Support, Non-U.S. Gov't United states Journal of medicinal chemistry J Med Chem. 1999 Nov 4;42(22):4473-8..
14 years ago by @pharmawuerz
show all tags
Cricetinae
Binding,
Humans
CHO
Purinergic
Rats
Competitive
Animals
inhibitors/metabolism
Receptor
Cyclic
Pyrazoles/*chemical
P1/*antagonists
Pyrimidines/*chemical
AMP/biosynthesis
Relationship
Structure-Activity
Brain/metabolism
Adenosine
synthesis/chemistry/metabolism/pharmacology
Cell
CricetinaeBinding,HumansCHOPurinergicRatsCompetitiveAnimalsinhibitors/metabolismReceptorCyclicPyrazoles/*chemicalP1/*antagonistsPyrimidines/*chemicalAMP/biosynthesisRelationshipStructure-ActivityBrain/metabolismAdenosinesynthesis/chemistry/metabolism/pharmacologyCell
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1Modulation of beta1-adrenoceptor activity by domain-specific antibodies and heart failure-associated autoantibodies
R. Jahns, V. Boivin, T. Krapf, G. Wallukat, F. Boege, and M. Lohse. J Am Coll Cardiol, 36 (4): 1280-7 (October 2000)Jahns, R Boivin, V Krapf, T Wallukat, G Boege, F Lohse, M J Comparative Study Research Support, Non-U.S. Gov't United states Journal of the American College of Cardiology J Am Coll Cardiol. 2000 Oct;36(4):1280-7..
14 years ago by @pharmawuerz
show all tags
Rabbits
effects/immunology/*metabolism
G/immunology
Biological
Transduction/drug
Middle
effects
Enzyme-Linked
Animals
Receptor
Blotting,
Cyclic
Mice
Aged
Immunodominant
Potentials/drug
AMP/metabolism
Heart
Markers/blood
Humans
Male
Immunoglobulin
Adrenergic
Failure/*immunology/metabolism
beta-1/drug
Proteins
Assay
Western
Epitopes/immunology/metabolism
Autoantibodies/immunology/*pharmacology
Immunosorbent
Membrane
Recombinant
Signal
Female
Rabbitseffects/immunology/*metabolismG/immunologyBiologicalTransduction/drugMiddleeffectsEnzyme-LinkedAnimalsReceptorBlotting,CyclicMiceAgedImmunodominantPotentials/drugAMP/metabolismHeartMarkers/bloodHumansMaleImmunoglobulinAdrenergicFailure/*immunology/metabolismbeta-1/drugProteinsAssayWesternEpitopes/immunology/metabolismAutoantibodies/immunology/*pharmacologyImmunosorbentMembraneRecombinantSignalFemale
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1Direct inhibition of cardiac hyperpolarization-activated cyclic nucleotide-gated pacemaker channels by clonidine
A. Knaus, X. Zong, N. Beetz, R. Jahns, M. Lohse, M. Biel, and L. Hein. Circulation, 115 (7): 872-80 (February 2007)Knaus, Anne Zong, Xiangang Beetz, Nadine Jahns, Roland Lohse, Martin J Biel, Martin Hein, Lutz Research Support, Non-U.S. Gov't United States Circulation Circulation. 2007 Feb 20;115(7):872-80. Epub 2007 Jan 29..
14 years ago by @pharmawuerz
show all tags
Channels/*antagonists
&
Proteins/antagonists
Ion
Nervous
Cation
effects
Animals
Nucleotide-Gated
Cyclic
Strains
Line
Mice
inhibitors/*drug
Bradycardia/chemically
Agents/*pharmacology
Clonidine/*pharmacology
Cardiovascular
Male
System/*drug
Sympathetic
induced
Channels
Muscle
Female
Cell
Channels/*antagonists&Proteins/antagonistsIonNervousCationeffectsAnimalsNucleotide-GatedCyclicStrainsLineMiceinhibitors/*drugBradycardia/chemicallyAgents/*pharmacologyClonidine/*pharmacologyCardiovascularMaleSystem/*drugSympatheticinducedChannelsMuscleFemaleCell
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1Internalization determinants of the parathyroid hormone receptor differentially regulate beta-arrestin/receptor association
J. Vilardaga, C. Krasel, S. Chauvin, T. Bambino, M. Lohse, and R. Nissenson. J Biol Chem, 277 (10): 8121-9 (March 2002)Vilardaga, Jean-Pierre Krasel, Cornelius Chauvin, Stephanie Bambino, Tom Lohse, Martin J Nissenson, Robert A DK 35323/DK/NIDDK NIH HHS/United States Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. United States The Journal of biological chemistry J Biol Chem. 2002 Mar 8;277(10):8121-9. Epub 2001 Nov 28..
14 years ago by @pharmawuerz
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Luminescent
Binding
Structure,
Tertiary
Cytoplasm/metabolism
Asparagine/chemistry
Membrane/metabolism
Protein
Receptor
Blotting,
Cyclic
DNA,
Line
Kinetics
Microscopy,
Transduction
Arrestins/*chemistry/*metabolism
Ligands
Mutation
Lysine/chemistry
Transport
AMP/metabolism
Green
Factors
Phosphorylation
Humans
Immunoblotting
Confocal
Time
Proteins/metabolism
Proteins
Western
Fluorescent
Parathyroid
Complementary/metabolism
Endocytosis
Signal
Hormone/*chemistry/*metabolism
Cell
LuminescentBindingStructure,TertiaryCytoplasm/metabolismAsparagine/chemistryMembrane/metabolismProteinReceptorBlotting,CyclicDNA,LineKineticsMicroscopy,TransductionArrestins/*chemistry/*metabolismLigandsMutationLysine/chemistryTransportAMP/metabolismGreenFactorsPhosphorylationHumansImmunoblottingConfocalTimeProteins/metabolismProteinsWesternFluorescentParathyroidComplementary/metabolismEndocytosisSignalHormone/*chemistry/*metabolismCell
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1Protein kinase cross-talk: membrane targeting of the beta-adrenergic receptor kinase by protein kinase C
R. Winstel, S. Freund, C. Krasel, E. Hoppe, and M. Lohse. Proc Natl Acad Sci U S A, 93 (5): 2105-9 (March 1996)Winstel, R Freund, S Krasel, C Hoppe, E Lohse, M J Research Support, Non-U.S. Gov't United states Proceedings of the National Academy of Sciences of the United States of America Proc Natl Acad Sci U S A. 1996 Mar 5;93(5):2105-9..
14 years ago by @pharmawuerz
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Epinephrine/pharmacology
Cricetinae
Compartmentation
Peptides/chemistry
Data
Sequence
Protein
beta-Adrenergic
effects
Animals
Membrane/enzymology
Receptor
Cyclic
Kinase
Kinases/*metabolism
Line
Activation/drug
C/*physiology
Transduction
Acid
Phosphorylation
Humans
CHO
Adrenergic
Proteins
alpha-1/*metabolism
Kinases
Molecular
Amino
Enzyme
Recombinant
Signal
AMP-Dependent
Cell
Epinephrine/pharmacologyCricetinaeCompartmentationPeptides/chemistryDataSequenceProteinbeta-AdrenergiceffectsAnimalsMembrane/enzymologyReceptorCyclicKinaseKinases/*metabolismLineActivation/drugC/*physiologyTransductionAcidPhosphorylationHumansCHOAdrenergicProteinsalpha-1/*metabolismKinasesMolecularAminoEnzymeRecombinantSignalAMP-DependentCell
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1Real-time monitoring of cAMP levels in living endothelial cells: thrombin transiently inhibits adenylyl cyclase 6
R. Werthmann, K. von Hayn, V. Nikolaev, M. Lohse, and M. Bunemann. J Physiol, 587 (Pt 16): 4091-104 (August 2009)Werthmann, R C von Hayn, K Nikolaev, V O Lohse, M J Bunemann, M Research Support, Non-U.S. Gov't England The Journal of physiology J Physiol. 2009 Aug 15;587(Pt 16):4091-104. Epub 2009 Jun 22..
14 years ago by @pharmawuerz
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Calcium/*metabolism
&
Humans
Cells/drug
inhibitors/*metabolism
Adenylate
Systems
Transduction/drug
Cyclase/*antagonists
Thrombin/*pharmacology
Cyclic
AMP/*metabolism
Computer
Endothelial
Cultured
effects/*physiology
effects/*metabolism
Signal
Cell
Calcium/*metabolism&HumansCells/druginhibitors/*metabolismAdenylateSystemsTransduction/drugCyclase/*antagonistsThrombin/*pharmacologyCyclicAMP/*metabolismComputerEndothelialCulturedeffects/*physiologyeffects/*metabolismSignalCell
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1Phosducin, potential role in modulation of olfactory signaling
I. Boekhoff, K. Touhara, S. Danner, J. Inglese, M. Lohse, H. Breer, and R. Lefkowitz. J Biol Chem, 272 (7): 4606-12 (February 1997)Boekhoff, I Touhara, K Danner, S Inglese, J Lohse, M J Breer, H Lefkowitz, R J HL16037/HL/NHLBI NIH HHS/United States Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. United states The Journal of biological chemistry J Biol Chem. 1997 Feb 14;272(7):4606-12..
14 years ago by @pharmawuerz
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Olfactory
*Protein-Serine-Threonine
Mutagenesis,
Rats
Kinases/metabolism
Protein
3
Animals
Proteins/genetics/*metabolism
Receptor
Site-Directed
Cyclic
Kinase
Transduction
Pathways/*metabolism
AMP/metabolism
Regulators
Phosphorylation
Protein-Tyrosine
Humans
Proteins/metabolism
Eye
*Signal
Kinases
Phosphoproteins/genetics/*metabolism
Membrane
G-Protein-Coupled
GTP-Binding
Sprague-Dawley
Olfactory*Protein-Serine-ThreonineMutagenesis,RatsKinases/metabolismProtein3AnimalsProteins/genetics/*metabolismReceptorSite-DirectedCyclicKinaseTransductionPathways/*metabolismAMP/metabolismRegulatorsPhosphorylationProtein-TyrosineHumansProteins/metabolismEye*SignalKinasesPhosphoproteins/genetics/*metabolismMembraneG-Protein-CoupledGTP-BindingSprague-Dawley
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1Mechanisms involved in adrenergic receptor desensitization
S. Collins, M. Bouvier, M. Lohse, J. Benovic, M. Caron, and R. Lefkowitz. Biochem Soc Trans, 18 (4): 541-4 (August 1990)Collins, S Bouvier, M Lohse, M J Benovic, J L Caron, M G Lefkowitz, R J HL16037/HL/NHLBI NIH HHS/United States Research Support, U.S. Gov't, P.H.S. Review England Biochemical Society transactions Biochem Soc Trans. 1990 Aug;18(4):541-4..
14 years ago by @pharmawuerz
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RNA,
Phosphorylation
Rhodopsin/metabolism
Kinases/metabolism
Adrenergic
Messenger/metabolism
Protein
beta/*metabolism
Receptor
Transduction/physiology
Cyclic
Signal
AMP/metabolism
RNA,PhosphorylationRhodopsin/metabolismKinases/metabolismAdrenergicMessenger/metabolismProteinbeta/*metabolismReceptorTransduction/physiologyCyclicSignalAMP/metabolism
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1Cyclic GMP from the surrounding somatic cells regulates cyclic AMP and meiosis in the mouse oocyte
R. Norris, W. Ratzan, M. Freudzon, L. Mehlmann, J. Krall, M. Movsesian, H. Wang, H. Ke, V. Nikolaev, and L. Jaffe. Development, 136 (11): 1869-78 (June 2009)Norris, Rachael P Ratzan, William J Freudzon, Marina Mehlmann, Lisa M Krall, Judith Movsesian, Matthew A Wang, Huanchen Ke, Hengming Nikolaev, Viacheslav O Jaffe, Laurinda A DK073499/DK/NIDDK NIH HHS/United States GM59791/GM/NIGMS NIH HHS/United States HD014939/HD/NICHD NIH HHS/United States Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. England Development (Cambridge, England) Development. 2009 Jun;136(11):1869-78..
14 years ago by @pharmawuerz
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Junctions/drug
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Luteinizing
Follicle/drug
Humans
effects/physiology
Nucleotide
Ovarian
Phosphodiesterases,
Type
3
Animals
Cyclic
Gap
AMP/*metabolism
Hormone/pharmacology/physiology
Oocytes/drug
Cultured
Mice
effects/*physiology
GMP/*physiology
Female
Cell
Junctions/drugMeiosis/drugLuteinizingFollicle/drugHumanseffects/physiologyNucleotideOvarianPhosphodiesterases,Type3AnimalsCyclicGapAMP/*metabolismHormone/pharmacology/physiologyOocytes/drugCulturedMiceeffects/*physiologyGMP/*physiologyFemaleCell
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1Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation
V. Nikolaev, A. Moshkov, A. Lyon, M. Miragoli, P. Novak, H. Paur, M. Lohse, Y. Korchev, S. Harding, and J. Gorelik. Science, 327 (5973): 1653-7 (March 2010)Nikolaev, Viacheslav O Moshkov, Alexey Lyon, Alexander R Miragoli, Michele Novak, Pavel Paur, Helen Lohse, Martin J Korchev, Yuri E Harding, Sian E Gorelik, Julia 084064/Wellcome Trust/United Kingdom Biotechnology and Biological Sciences Research Council/United Kingdom Medical Research Council/United Kingdom Research Support, Non-U.S. Gov't United States Science (New York, N.Y.) Science. 2010 Mar 26;327(5973):1653-7. Epub 2010 Feb 25..
14 years ago by @pharmawuerz
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Cardiac/*metabolism/ultrastructure
Compartmentation
Failure/*metabolism/*pathology
Sarcolemma/*metabolism/ultrastructure
Rats
Kinases/metabolism
Knockout
Protein
Chronic
Animals
Receptor
beta-1/genetics/metabolism
Cyclic
AMP/*metabolism
Microscopy/methods
Transfer
Mice
Resonance
Transduction
Cytosol/metabolism
Heart
Disease
Myocytes,
Membrane/*metabolism/ultrastructure
Male
Fluorescence
Transgenic
Adrenergic
beta-2/genetics/*metabolism
Energy
Signal
AMP-Dependent
Sprague-Dawley
Cell
Cardiac/*metabolism/ultrastructureCompartmentationFailure/*metabolism/*pathologySarcolemma/*metabolism/ultrastructureRatsKinases/metabolismKnockoutProteinChronicAnimalsReceptorbeta-1/genetics/metabolismCyclicAMP/*metabolismMicroscopy/methodsTransferMiceResonanceTransductionCytosol/metabolismHeartDiseaseMyocytes,Membrane/*metabolism/ultrastructureMaleFluorescenceTransgenicAdrenergicbeta-2/genetics/*metabolismEnergySignalAMP-DependentSprague-DawleyCell
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1Differential conformational requirements for activation of G proteins and the regulatory proteins arrestin and G protein-coupled receptor kinase in the G protein-coupled receptor for parathyroid hormone (PTH)/PTH-related protein
J. Vilardaga, M. Frank, C. Krasel, C. Dees, R. Nissenson, and M. Lohse. J Biol Chem, 276 (36): 33435-43 (September 2001)Vilardaga, J P Frank, M Krasel, C Dees, C Nissenson, R A Lohse, M J Research Support, Non-U.S. Gov't United States The Journal of biological chemistry J Biol Chem. 2001 Sep 7;276(36):33435-43. Epub 2001 May 31..
14 years ago by @pharmawuerz
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COS
Protein-Serine-Threonine
Competitive
Inhibitory
Kinetics
Mutation
Conformation
Factors
Compounds/pharmacology
Hormone/*metabolism
Hormone,
Activation
Immunoblotting
Ions/metabolism
Chlorides/pharmacology
Time
Arrestin/*metabolism
Dose-Response
50
Relationship,
Phosphates/metabolism
Cell
Histidine/chemistry
Binding
Inositol
Sites
Zinc
Concentration
Membrane/metabolism
Protein
1
Type
Animals
Receptor
Cyclic
Kinases/*metabolism
Zinc/metabolism
Transduction
Ligands
AMP/metabolism
Phosphorylation
Binding,
Arrestins/metabolism
Proteins/metabolism
GTP-Binding
Enzyme
Parathyroid
Signal
Drug
COSProtein-Serine-ThreonineCompetitiveInhibitoryKineticsMutationConformationFactorsCompounds/pharmacologyHormone/*metabolismHormone,ActivationImmunoblottingIons/metabolismChlorides/pharmacologyTimeArrestin/*metabolismDose-Response50Relationship,Phosphates/metabolismCellHistidine/chemistryBindingInositolSitesZincConcentrationMembrane/metabolismProtein1TypeAnimalsReceptorCyclicKinases/*metabolismZinc/metabolismTransductionLigandsAMP/metabolismPhosphorylationBinding,Arrestins/metabolismProteins/metabolismGTP-BindingEnzymeParathyroidSignalDrug
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1Spatiotemporal dynamics of beta-adrenergic cAMP signals and L-type Ca2+ channel regulation in adult rat ventricular myocytes: role of phosphodiesterases
J. Leroy, A. Abi-Gerges, V. Nikolaev, W. Richter, P. Lechene, J. Mazet, M. Conti, R. Fischmeister, and G. Vandecasteele. Circ Res, 102 (9): 1091-100 (May 2008)Leroy, Jerome Abi-Gerges, Aniella Nikolaev, Viacheslav O Richter, Wito Lechene, Patrick Mazet, Jean-Luc Conti, Marco Fischmeister, Rodolphe Vandecasteele, Gregoire HD20788/HD/NICHD NIH HHS/United States Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't United States Circulation research Circ Res. 2008 May 9;102(9):1091-100. Epub 2008 Mar 27..
14 years ago by @pharmawuerz
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Techniques
Fluorescence/methods
Nucleotide
Rats
Biosensing
Wistar
Exchange
effects
*Myocardial
Potentials
AMP/*metabolism
Inhibitors/pharmacology
Kinetics
Transfer
Resonance
effects/*metabolism
Calcium
Activation
Phosphodiesterases,
Sarcolemma/metabolism
Dose-Response
L-Type/*metabolism
Membrane
Cultured
Relationship,
Energy
Cell
Phosphodiesterase
&
inhibitors/*metabolism
Contraction/drug
4/antagonists
Channels,
Transduction/drug
Ventricles/metabolism
Kinases/metabolism
Protein
Cation
Type
Cardiac/drug
Animals
Receptor
Nucleotide-Gated
Cyclic
3/antagonists
Quinolones/pharmacology
Microscopy,
beta/drug
beta-Agonists/pharmacology
Cytosol/metabolism
Isoproterenol/pharmacology
Factors/genetics/metabolism
Heart
Phosphorylation
Myocytes,
effects/enzymology/*metabolism
Male
Fluorescence
Transfection
Adrenergic
Guanine
*Signal
Channels/genetics/metabolism
Enzyme
AMP-Dependent
4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone/pharmacology
Drug
TechniquesFluorescence/methodsNucleotideRatsBiosensingWistarExchangeeffects*MyocardialPotentialsAMP/*metabolismInhibitors/pharmacologyKineticsTransferResonanceeffects/*metabolismCalciumActivationPhosphodiesterases,Sarcolemma/metabolismDose-ResponseL-Type/*metabolismMembraneCulturedRelationship,EnergyCellPhosphodiesterase&inhibitors/*metabolismContraction/drug4/antagonistsChannels,Transduction/drugVentricles/metabolismKinases/metabolismProteinCationTypeCardiac/drugAnimalsReceptorNucleotide-GatedCyclic3/antagonistsQuinolones/pharmacologyMicroscopy,beta/drugbeta-Agonists/pharmacologyCytosol/metabolismIsoproterenol/pharmacologyFactors/genetics/metabolismHeartPhosphorylationMyocytes,effects/enzymology/*metabolismMaleFluorescenceTransfectionAdrenergicGuanine*SignalChannels/genetics/metabolismEnzymeAMP-Dependent4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone/pharmacologyDrug
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1(3)HMRE 3008F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors
K. Varani, S. Merighi, S. Gessi, K. Klotz, E. Leung, P. Baraldi, B. Cacciari, R. Romagnoli, G. Spalluto, and P. Borea. Mol Pharmacol, 57 (5): 968-75 (May 2000)Varani, K Merighi, S Gessi, S Klotz, K N Leung, E Baraldi, P G Cacciari, B Romagnoli, R Spalluto, G Borea, P A United states Molecular pharmacology Mol Pharmacol. 2000 May;57(5):968-75..
14 years ago by @pharmawuerz
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Cricetinae
&
Radioligand
Compounds/chemistry/*pharmacology
Rats
Phenylurea
derivatives/pharmacology
Competitive
Animals
inhibitors/metabolism
Receptor
Cyclic
Cyclase/antagonists
Triazoles/chemistry/*pharmacology
Adenosine
AMP/metabolism
inhibitors
Binding,
Humans
Tritium
Adenosine/analogs
CHO
Adenylate
Purinergic
Assay
A3
Dose-Response
P1/*antagonists
Relationship,
Cell
Drug
Cricetinae&RadioligandCompounds/chemistry/*pharmacologyRatsPhenylureaderivatives/pharmacologyCompetitiveAnimalsinhibitors/metabolismReceptorCyclicCyclase/antagonistsTriazoles/chemistry/*pharmacologyAdenosineAMP/metabolisminhibitorsBinding,HumansTritiumAdenosine/analogsCHOAdenylatePurinergicAssayA3Dose-ResponseP1/*antagonistsRelationship,CellDrug
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1N6-methoxy-2-alkynyladenosine derivatives as highly potent and selective ligands at the human A3 adenosine receptor
R. Volpini, D. Ben, C. Lambertucci, S. Taffi, S. Vittori, K. Klotz, and G. Cristalli. J Med Chem, 50 (6): 1222-30 (March 2007)Volpini, Rosaria Dal Ben, Diego Lambertucci, Catia Taffi, Sara Vittori, Sauro Klotz, Karl-Norbert Cristalli, Gloria Research Support, Non-U.S. Gov't United States Journal of medicinal chemistry J Med Chem. 2007 Mar 22;50(6):1222-30. Epub 2007 Feb 20..
14 years ago by @pharmawuerz
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derivatives/*chemical
Adenosine/*analogs
Cricetinae
&
Radioligand
A3/*agonists
Sequence
Animals
Receptor
Cyclic
Relationship
Ligands
*Models,
Structure-Activity
Adenosine
Rhodopsin/chemistry
Acid
Cricetulus
Humans
Proteins/agonists
CHO
Assay
Molecular
Homology,
AMP/biosynthesis
synthesis/chemistry/pharmacology
Amino
Recombinant
Alkynes/*chemical
Cell
derivatives/*chemicalAdenosine/*analogsCricetinae&RadioligandA3/*agonistsSequenceAnimalsReceptorCyclicRelationshipLigands*Models,Structure-ActivityAdenosineRhodopsin/chemistryAcidCricetulusHumansProteins/agonistsCHOAssayMolecularHomology,AMP/biosynthesissynthesis/chemistry/pharmacologyAminoRecombinantAlkynes/*chemicalCell
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1The galanin receptor type 2 initiates multiple signaling pathways in small cell lung cancer cells by coupling to G(q), G(i) and G(12) proteins
N. Wittau, R. Grosse, F. Kalkbrenner, A. Gohla, G. Schultz, and T. Gudermann. Oncogene, 19 (37): 4199-209 (August 2000)Wittau, N Grosse, R Kalkbrenner, F Gohla, A Schultz, G Gudermann, T England Oncogene Oncogene. 2000 Aug 31;19(37):4199-209..
14 years ago by @pharmawuerz
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Galanin,
Protein/physiology
Cells/drug
COS
Adhesion
Protein-Serine-Threonine
Neoplasm
effects
Toxin
Kinase
Intracellular
Inhibitors/pharmacology
Cell/metabolism/*pathology
Carcinoma,
Mice
effects/*physiology
inhibitors/physiology
Mitogen-Activated
Calcium
Humans
AMP/physiology
Phospholipases/metabolism
inhibitors/*physiology
Bordetella/pharmacology
Factors,
rhoA
Tumor
Phosphates/metabolism
Cell
Pertussis
Small
Inositol
Heterotrimeric
&
Proteins/antagonists
Proteins/genetics/physiology
Kinases/metabolism
Protein
Proteins/*physiology
2
Neuropeptide/drug
Type
1-Methyl-3-isobutylxanthine/pharmacology
3
Signaling
Animals
Receptor
Cyclic
Cultured/metabolism
C/antagonists
Fusion
Isoproterenol/pharmacology
Galanin/metabolism/pharmacology
C
Actins/metabolism
Galanin
Lung
rho-Associated
Gi-Go/*physiology
Diacylglycerol-Lyase
Peptides
Virulence
Gohla
Microfilaments/metabolism
Transfection
G12-G13
Proteins
Indoles/pharmacology
3T3
Phosphatidylinositol
Kinases
alpha
Gq-G11
Kinases/physiology
1/metabolism
and
GTP-Binding
Maleimides/pharmacology
Enzyme
Signaling/drug
Recombinant
Neoplasms/metabolism/*pathology
Subunits,
Galanin,Protein/physiologyCells/drugCOSAdhesionProtein-Serine-ThreonineNeoplasmeffectsToxinKinaseIntracellularInhibitors/pharmacologyCell/metabolism/*pathologyCarcinoma,Miceeffects/*physiologyinhibitors/physiologyMitogen-ActivatedCalciumHumansAMP/physiologyPhospholipases/metabolisminhibitors/*physiologyBordetella/pharmacologyFactors,rhoATumorPhosphates/metabolismCellPertussisSmallInositolHeterotrimeric&Proteins/antagonistsProteins/genetics/physiologyKinases/metabolismProteinProteins/*physiology2Neuropeptide/drugType1-Methyl-3-isobutylxanthine/pharmacology3SignalingAnimalsReceptorCyclicCultured/metabolismC/antagonistsFusionIsoproterenol/pharmacologyGalanin/metabolism/pharmacologyCActins/metabolismGalaninLungrho-AssociatedGi-Go/*physiologyDiacylglycerol-LyasePeptidesVirulenceGohlaMicrofilaments/metabolismTransfectionG12-G13ProteinsIndoles/pharmacology3T3PhosphatidylinositolKinasesalphaGq-G11Kinases/physiology1/metabolismandGTP-BindingMaleimides/pharmacologyEnzymeSignaling/drugRecombinantNeoplasms/metabolism/*pathologySubunits,
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1Peptide inhibitors of G protein-coupled receptor kinases
R. Winstel, H. Ihlenfeldt, G. Jung, C. Krasel, and M. Lohse. Biochem Pharmacol, 70 (7): 1001-8 (October 2005)Winstel, Rainer Ihlenfeldt, Hans-Georg Jung, Gunther Krasel, Cornelius Lohse, Martin J Research Support, Non-U.S. Gov't England Biochemical pharmacology Biochem Pharmacol. 2005 Oct 1;70(7):1001-8..
14 years ago by @pharmawuerz
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Acid
Phosphorylation
Protein-Tyrosine
&
Data
Sequence
Proteins/metabolism
inhibitors/metabolism
Receptor
Molecular
Kinases/*antagonists
Inhibitors/chemistry/*pharmacology
Cyclic
Peptides/chemistry/*pharmacology
GTP-Binding
Enzyme
Amino
AMP/metabolism
AcidPhosphorylationProtein-Tyrosine&DataSequenceProteins/metabolisminhibitors/metabolismReceptorMolecularKinases/*antagonistsInhibitors/chemistry/*pharmacologyCyclicPeptides/chemistry/*pharmacologyGTP-BindingEnzymeAminoAMP/metabolism
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1Cytoplasmic cAMP concentrations in intact cardiac myocytes
R. Iancu, G. Ramamurthy, S. Warrier, V. Nikolaev, M. Lohse, S. Jones, and R. Harvey. Am J Physiol Cell Physiol, 295 (2): C414-22 (August 2008)Iancu, Radu V Ramamurthy, Gopalakrishnan Warrier, Sunita Nikolaev, Viacheslav O Lohse, Martin J Jones, Stephen W Harvey, Robert D Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't United States American journal of physiology. Cell physiology Am J Physiol Cell Physiol. 2008 Aug;295(2):C414-22. Epub 2008 Jun 11..
14 years ago by @pharmawuerz
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Luminescent
Pigs
Compartmentation
Techniques
&
Nucleotide
Acetylcholine/pharmacology
Biological
Biosensing
Exchange
1-Methyl-3-isobutylxanthine/pharmacology
Animals
Receptor
Cyclic
Simulation
M2/agonists
Transfer
Resonance
effects/*metabolism
Models,
beta-Agonists/pharmacology
inhibitors
Factors/genetics/metabolism
Guinea
Myocytes,
beta-1/antagonists
Cytoplasm/*metabolism
Proteins/genetics/metabolism
Fluorescence
Muscarinic
Cardiac/cytology/drug
Transfection
Adrenergic
Guanine
Transduction/*physiology
Computer
Cultured
Energy
Signal
Cell
AMP/analysis/*metabolism
LuminescentPigsCompartmentationTechniques&NucleotideAcetylcholine/pharmacologyBiologicalBiosensingExchange1-Methyl-3-isobutylxanthine/pharmacologyAnimalsReceptorCyclicSimulationM2/agonistsTransferResonanceeffects/*metabolismModels,beta-Agonists/pharmacologyinhibitorsFactors/genetics/metabolismGuineaMyocytes,beta-1/antagonistsCytoplasm/*metabolismProteins/genetics/metabolismFluorescenceMuscarinicCardiac/cytology/drugTransfectionAdrenergicGuanineTransduction/*physiologyComputerCulturedEnergySignalCellAMP/analysis/*metabolism
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1Nitric oxide signaling: no longer simply on or off
S. Cary, J. Winger, E. Derbyshire, and M. Marletta. Trends Biochem Sci, 31 (4): 231--9 (April 2006)
15 years ago by @fdiehl
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Animals,
GMP,
Cyclase,
Nitric
Transduction,
Heme,
Humans,
Oxide
Synthase,
Guanylate
Cyclic
Models:
Chemical,
Signal
Animals,GMP,Cyclase,NitricTransduction,Heme,Humans,OxideSynthase,GuanylateCyclicModels:Chemical,Signal
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1Coupled gating between cardiac calcium release channels (ryanodine receptors).
S. Marx, J. Gaburjakova, M. Gaburjakova, C. Henrikson, K. Ondrias, and A. Marks. Circ. Res., 88 (11): 1151--1158 (June 2001)
16 years ago by @hake
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Chambers,
p27,
Ion
Homozygote,
Adhesion,
Cycle
Percutaneous
Kinase
Cyclin-Dependent
Inhibitor
Toxins,
Inbred
Animals,
Density
Agents,
Aorta,
Clinical
Angioplasty,
Cells,
Arteriosclerosis,
Dose-Response
Coronary
Membrane
Relationship,
Diffusion
Graft
Barium,
Division,
Channel
Contraction,
Potentials,
Protein
Survival,
2,
Down-Regulation,
Group
K,
Immunoblotting,
Dilated,
Myocardium,
Heterozygote,
Transferases,
Culture,
Hyperplasia,
(Alcohol
Non-U.S.
Factor
Drug,
Enzyme
Bilayers,
AMP-Dependent
Botulinum
Calcineurin,
Coloring
Mice,
Macromolecular
Lipid
Humans,
Kinases,
4,
Gating,
Caffeine,
Count,
Microtubule-Associated
Coronary,
Growth
C57BL,
Dogs,
Trials,
Calcium-Binding
ADP
CDC2-CDC28
Substances,
Cardiomyopathy,
Muscle,
Death,
Carrier
Magnesium
Myosin
Ribose
Movement,
Cell
Phosphotransferases
P.H.S.,
Cyclic
Centrifugation,
Microsomes,
Chains,
Knockout,
Activation,
Fibroblast
Heavy
Gradient,
Gov't,
Chloride,
Proteins,
Cardiac,
Myocardial
Phosphorylation,
Occlusion,
Cultured,
Chambers,p27,IonHomozygote,Adhesion,CyclePercutaneousKinaseCyclin-DependentInhibitorToxins,InbredAnimals,DensityAgents,Aorta,ClinicalAngioplasty,Cells,Arteriosclerosis,Dose-ResponseCoronaryMembraneRelationship,DiffusionGraftBarium,Division,ChannelContraction,Potentials,ProteinSurvival,2,Down-Regulation,GroupK,Immunoblotting,Dilated,Myocardium,Heterozygote,Transferases,Culture,Hyperplasia,(AlcoholNon-U.S.FactorDrug,EnzymeBilayers,AMP-DependentBotulinumCalcineurin,ColoringMice,MacromolecularLipidHumans,Kinases,4,Gating,Caffeine,Count,Microtubule-AssociatedCoronary,GrowthC57BL,Dogs,Trials,Calcium-BindingADPCDC2-CDC28Substances,Cardiomyopathy,Muscle,Death,CarrierMagnesiumMyosinRiboseMovement,CellPhosphotransferasesP.H.S.,CyclicCentrifugation,Microsomes,Chains,Knockout,Activation,FibroblastHeavyGradient,Gov't,Chloride,Proteins,Cardiac,MyocardialPhosphorylation,Occlusion,Cultured,
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1Potentiation of fractional sarcoplasmic reticulum calcium release by total and free intra-sarcoplasmic reticulum calcium concentration.
T. Shannon, K. Ginsburg, and D. Bers. Biophys. J., 78 (1): 334--343 (January 2000)
16 years ago by @hake
show all tags
Ruthenium
Mice,
{C}a$^{2+}$-Transporting
Calcium,
Failure,
Ion
beta-Agonists,
Biological,
Electric
Simulation,
Transport,
Humans,
Stimulation,
Kinases,
Intracellular
Techniques,
Caffeine,
Thermodynamics,
Membrane,
10620297
Ventricles,
Animals,
Calcium
Dogs,
Calcium-Binding
Regulation,
Research
Time
Cells,
Fibers,
Factors,
Allosteric
U.S.
Membrane
Tetracaine,
Muscle
Cell
Patch-Clamp
Membranes,
Cytosol,
Channels,
Biological
Mutagenesis,
Catalytic
Contraction,
Potentials,
Support,
Sodium-Calcium
Congestive,
Protein
Reticulum,
P.H.S.,
Cyclic
Isoproterenol,
ATPase,
Microsomes,
Domain,
Knockout,
Nickel,
Activation,
Models,
Exchanger,
Rabbits,
Red,
Adenosine
Ferrets,
Signaling,
Action
Heart
Hydrolysis,
Myocytes,
Binding,
Myocardium,
Cardiovascular,
Sarcoplasmic
Gov't,
Adrenergic
Triphosphate,
Kinetics,
Proteins,
Thapsigargin,
Cardiac,
Non-U.S.
Inhibitors,
Myocardial
Computer
Diastole,
Phosphorylation,
Enzyme
AMP-Dependent
Cultured,
Heart,
RutheniumMice,{C}a$^{2+}$-TransportingCalcium,Failure,Ionbeta-Agonists,Biological,ElectricSimulation,Transport,Humans,Stimulation,Kinases,IntracellularTechniques,Caffeine,Thermodynamics,Membrane,10620297Ventricles,Animals,CalciumDogs,Calcium-BindingRegulation,ResearchTimeCells,Fibers,Factors,AllostericU.S.MembraneTetracaine,MuscleCellPatch-ClampMembranes,Cytosol,Channels,BiologicalMutagenesis,CatalyticContraction,Potentials,Support,Sodium-CalciumCongestive,ProteinReticulum,P.H.S.,CyclicIsoproterenol,ATPase,Microsomes,Domain,Knockout,Nickel,Activation,Models,Exchanger,Rabbits,Red,AdenosineFerrets,Signaling,ActionHeartHydrolysis,Myocytes,Binding,Myocardium,Cardiovascular,SarcoplasmicGov't,AdrenergicTriphosphate,Kinetics,Proteins,Thapsigargin,Cardiac,Non-U.S.Inhibitors,MyocardialComputerDiastole,Phosphorylation,EnzymeAMP-DependentCultured,Heart,
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1Anion transport in heart.
J. Hume, D. Duan, M. Collier, J. Yamazaki, and B. Horowitz. Physiol. Rev., 80 (1): 31--81 (January 2000)
16 years ago by @hake
show all tags
p-Trifluoromethoxyphenylhydrazone,
Infusions,
Intravenous,
Ion
Edetic
Acetazolamide,
Transport,
Diphosphates,
Transport
Inbred
Animals,
Acid-Base
Female,
Media,
coli,
Agents,
Transmembrane
Cells,
Blood
Solutions,
Carbonyl
Dose-Response
Concentration,
Capillary
Anions,
AMP,
Relationship,
Anhydrase
Alkalies,
Binding
Escherichia
Channel
Biological
Carbon
Exercise,
Adult,
Cations,
Divalent,
Chickens,
Acids,
Dioxide,
Models,
Conductance
Permeability,
Heart
In
Cardiolipins,
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic
Complex
Triphosphate,
Glycogen,
Expression,
Gene
T,
Drug,
Heart,
Sites,
Equilibrium,
Calcium,
Electric
Size,
Animal,
Humans,
Fibrosis
Glyburide,
Disease
Calcium
C57BL,
Chlorides,
Vitro,
Hypoglycemic
Carrier
Hypotonic
Regulator,
Cardiotonic
Culture
Cell
IV,
Pressure,
Hydrogen-Ion
Cystic
Channels,
Carbonic
Acid,
Chloride
Cattle,
Cyclic
Isoproterenol,
Adenosine
Cyanide
Arsenates,
Blockers,
Hypertension,
Anthranilic
Proteins,
Electron
Antibodies,
Inhibitors,
Rate,
Cultured,
Conductivity,
p-Trifluoromethoxyphenylhydrazone,Infusions,Intravenous,IonEdeticAcetazolamide,Transport,Diphosphates,TransportInbredAnimals,Acid-BaseFemale,Media,coli,Agents,TransmembraneCells,BloodSolutions,CarbonylDose-ResponseConcentration,CapillaryAnions,AMP,Relationship,AnhydraseAlkalies,BindingEscherichiaChannelBiologicalCarbonExercise,Adult,Cations,Divalent,Chickens,Acids,Dioxide,Models,ConductancePermeability,HeartInCardiolipins,4,4'-Diisothiocyanostilbene-2,2'-DisulfonicComplexTriphosphate,Glycogen,Expression,GeneT,Drug,Heart,Sites,Equilibrium,Calcium,ElectricSize,Animal,Humans,FibrosisGlyburide,DiseaseCalciumC57BL,Chlorides,Vitro,HypoglycemicCarrierHypotonicRegulator,CardiotonicCultureCellIV,Pressure,Hydrogen-IonCysticChannels,CarbonicAcid,ChlorideCattle,CyclicIsoproterenol,AdenosineCyanideArsenates,Blockers,Hypertension,AnthranilicProteins,ElectronAntibodies,Inhibitors,Rate,Cultured,Conductivity,
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1Cardiac excitation-contraction coupling: role of membrane potential in regulation of contraction.
G. Ferrier, and S. Howlett. Am. J. Physiol. Heart Circ. Physiol., 280 (5): H1928--H1944 (May 2001)
16 years ago by @hake
show all tags
Phosphodiesterase
Calcium,
Amrinone,
Channel
Channels,
Contraction,
Potentials,
Support,
11299192
Humans,
Reticulum,
Stimulation,
Cyclic
Male,
1-Methyl-3-isobutylxanthine,
Animals,
Calcium
Guinea
In
Myocardium,
Blockers,
Sarcoplasmic
Gov't,
Research
Comparative
Electrophysiology,
Forskolin,
Vitro,
Non-U.S.
Chemical,
Inhibitors,
Myocardial
Membrane
AMP,
Study,
Enzyme
Pigs,
Activators,
Heart,
PhosphodiesteraseCalcium,Amrinone,ChannelChannels,Contraction,Potentials,Support,11299192Humans,Reticulum,Stimulation,CyclicMale,1-Methyl-3-isobutylxanthine,Animals,CalciumGuineaInMyocardium,Blockers,SarcoplasmicGov't,ResearchComparativeElectrophysiology,Forskolin,Vitro,Non-U.S.Chemical,Inhibitors,MyocardialMembraneAMP,Study,EnzymePigs,Activators,Heart,
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1Single-channel properties of L-type calcium channels from failing human ventricle.
R. Handrock, F. Schr�der, S. Hirt, A. Haverich, C. Mittmann, and S. Herzig. Cardiovasc. Res., 37 (2): 445--455 (February 1998)
16 years ago by @hake
show all tags
Calcium,
Failure,
Ion
Reference
l
L-Type,
Middle
Cardiomyopathies,
Humans,
Techniques,
Gating,
Monophosphate,
Ventricles,
Calcium
Female,
Cyclosporine,
Research
Time
Cells,
Cardiomyopathy,
Factors,
U.S.
Myocardia,
Membrane
AMP,
Muscle
Cell
9614499
Patch-Clamp
Aged,
Agonists,
Barium,
Channel
Channels,
Potentials,
Support,
Congestive,
Values,
Adult,
Ischemia,
P.H.S.,
Cyclic
Male,
8-Bromo
Atria,
Line,
Adenosine
Heart
Dilated,
Gov't,
Comparative
Kinetics,
Proteins,
Non-U.S.
Pyrroles,
Study,
Probability,
Recombinant
Cultured,
Calcineurin,
Heart,
Calcium,Failure,IonReferencelL-Type,MiddleCardiomyopathies,Humans,Techniques,Gating,Monophosphate,Ventricles,CalciumFemale,Cyclosporine,ResearchTimeCells,Cardiomyopathy,Factors,U.S.Myocardia,MembraneAMP,MuscleCell9614499Patch-ClampAged,Agonists,Barium,ChannelChannels,Potentials,Support,Congestive,Values,Adult,Ischemia,P.H.S.,CyclicMale,8-BromoAtria,Line,AdenosineHeartDilated,Gov't,ComparativeKinetics,Proteins,Non-U.S.Pyrroles,Study,Probability,RecombinantCultured,Calcineurin,Heart,
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1Localization of PKA phosphorylation site, Ser(2030), in the three-dimensional structure of cardiac ryanodine receptor.
P. Jones, X. Meng, B. Xiao, S. Cai, J. Bolstad, T. Wagenknecht, Z. Liu, and S. Chen. Biochem. J., 410 (2): 261--270 (March 2008)
16 years ago by @hake
show all tags
effects/metabolism;
Humans;
Calcium,
Polymorphism,
Conformation;
Microscopy;
effects/genetics/metabolism;
Serine;
Computer-Assisted;
metabolism;
Protein
enzymology;
Receptor
Kinases,
Cyclic
pharmacology;
Cryoelectron
Caffeine,
Single
Kidney,
Models,
Molecular;
Ryanodine
Nucleotide;
Calcium
Myocardium,
Line;
chemistry/drug
physiology;
Transfection
embryology;
Image
Ryanodine,
metabolism/pharmacology;
Proteins,
Phosphorylation;
Channel,
Recombinant
Processing,
AMP-Dependent
Cell
Heart,
Release
effects/metabolism;Humans;Calcium,Polymorphism,Conformation;Microscopy;effects/genetics/metabolism;Serine;Computer-Assisted;metabolism;Proteinenzymology;ReceptorKinases,Cyclicpharmacology;CryoelectronCaffeine,SingleKidney,Models,Molecular;RyanodineNucleotide;CalciumMyocardium,Line;chemistry/drugphysiology;Transfectionembryology;ImageRyanodine,metabolism/pharmacology;Proteins,Phosphorylation;Channel,RecombinantProcessing,AMP-DependentCellHeart,Release
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1Chloride conductance pathways in heart.
J. Hume, and R. Harvey. Am. J. Physiol., 261 (3 Pt 1): C399--C412 (September 1991)
16 years ago by @hake
show all tags
Animals,
Female,
Ion
Channels,
Gov't,
Research
Potentials,
Support,
Chloride
Chlorides,
Electrophysiology,
P.H.S.,
Proteins,
U.S.
Cyclic
Non-U.S.
Membrane
AMP,
Pregnancy,
1716049
Heart,
Animals,Female,IonChannels,Gov't,ResearchPotentials,Support,ChlorideChlorides,Electrophysiology,P.H.S.,Proteins,U.S.CyclicNon-U.S.MembraneAMP,Pregnancy,1716049Heart,
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1Phospholamban decreases the energetic efficiency of the sarcoplasmic reticulum Ca pump.
T. Shannon, G. Chu, E. Kranias, and D. Bers. J. Biol. Chem., 276 (10): 7195--7201 (March 2001)
16 years ago by @hake
show all tags
Ruthenium
Mice,
{C}a$^{2+}$-Transporting
Calcium,
Failure,
Ion
beta-Agonists,
Biological,
Electric
Simulation,
Transport,
Humans,
Stimulation,
Kinases,
Intracellular
Caffeine,
Thermodynamics,
Membrane,
Ventricles,
Animals,
Calcium
Dogs,
Calcium-Binding
Regulation,
Research
Time
Cells,
Fibers,
Factors,
Allosteric
U.S.
Membrane
Tetracaine,
Muscle
Cell
Membranes,
Cytosol,
Channels,
Biological
Mutagenesis,
Catalytic
Contraction,
Potentials,
Support,
Sodium-Calcium
Congestive,
11087739
Protein
Reticulum,
P.H.S.,
Cyclic
Isoproterenol,
ATPase,
Microsomes,
Domain,
Knockout,
Nickel,
Activation,
Models,
Exchanger,
Rabbits,
Red,
Adenosine
Ferrets,
Signaling,
Action
Heart
Hydrolysis,
Myocytes,
Binding,
Myocardium,
Cardiovascular,
Sarcoplasmic
Gov't,
Adrenergic
Triphosphate,
Kinetics,
Proteins,
Thapsigargin,
Cardiac,
Non-U.S.
Inhibitors,
Myocardial
Computer
Diastole,
Phosphorylation,
Enzyme
AMP-Dependent
Cultured,
Heart,
RutheniumMice,{C}a$^{2+}$-TransportingCalcium,Failure,Ionbeta-Agonists,Biological,ElectricSimulation,Transport,Humans,Stimulation,Kinases,IntracellularCaffeine,Thermodynamics,Membrane,Ventricles,Animals,CalciumDogs,Calcium-BindingRegulation,ResearchTimeCells,Fibers,Factors,AllostericU.S.MembraneTetracaine,MuscleCellMembranes,Cytosol,Channels,BiologicalMutagenesis,CatalyticContraction,Potentials,Support,Sodium-CalciumCongestive,11087739ProteinReticulum,P.H.S.,CyclicIsoproterenol,ATPase,Microsomes,Domain,Knockout,Nickel,Activation,Models,Exchanger,Rabbits,Red,AdenosineFerrets,Signaling,ActionHeartHydrolysis,Myocytes,Binding,Myocardium,Cardiovascular,SarcoplasmicGov't,AdrenergicTriphosphate,Kinetics,Proteins,Thapsigargin,Cardiac,Non-U.S.Inhibitors,MyocardialComputerDiastole,Phosphorylation,EnzymeAMP-DependentCultured,Heart,
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1Reverse mode of the sarcoplasmic reticulum calcium pump and load-dependent cytosolic calcium decline in voltage-clamped cardiac ventricular myocytes.
T. Shannon, K. Ginsburg, and D. Bers. Biophys. J., 78 (1): 322--333 (January 2000)
16 years ago by @hake
show all tags
Ruthenium
Mice,
{C}a$^{2+}$-Transporting
Calcium,
Failure,
Ion
beta-Agonists,
Biological,
Electric
Simulation,
Transport,
Humans,
Stimulation,
Kinases,
Troponin,
Intracellular
Techniques,
Caffeine,
Thermodynamics,
10620296
Membrane,
Ventricles,
Animals,
Calcium
Dogs,
Calcium-Binding
Regulation,
Research
Time
Cells,
Fibers,
Factors,
Allosteric
U.S.
Membrane
Tetracaine,
Muscle
lular
Cell
Patch-Clamp
Membranes,
Cytosol,
Channels,
Biological
Mutagenesis,
Catalytic
Contraction,
Potentials,
Support,
Sodium-Calcium
Congestive,
Protein
Reticulum,
P.H.S.,
Cyclic
Isoproterenol,
ATPase,
Microsomes,
Domain,
Knockout,
Nickel,
Activation,
Intracel,
Models,
Exchanger,
Rabbits,
Red,
Adenosine
Ferrets,
Signaling,
Action
Heart
Hydrolysis,
Myocytes,
Binding,
Myocardium,
Cardiovascular,
Sarcoplasmic
Gov't,
Adrenergic
Triphosphate,
Kinetics,
Proteins,
Thapsigargin,
Cardiac,
Non-U.S.
Inhibitors,
Myocardial
Computer
Diastole,
Phosphorylation,
Enzyme
AMP-Dependent
Cultured,
Heart,
RutheniumMice,{C}a$^{2+}$-TransportingCalcium,Failure,Ionbeta-Agonists,Biological,ElectricSimulation,Transport,Humans,Stimulation,Kinases,Troponin,IntracellularTechniques,Caffeine,Thermodynamics,10620296Membrane,Ventricles,Animals,CalciumDogs,Calcium-BindingRegulation,ResearchTimeCells,Fibers,Factors,AllostericU.S.MembraneTetracaine,MusclelularCellPatch-ClampMembranes,Cytosol,Channels,BiologicalMutagenesis,CatalyticContraction,Potentials,Support,Sodium-CalciumCongestive,ProteinReticulum,P.H.S.,CyclicIsoproterenol,ATPase,Microsomes,Domain,Knockout,Nickel,Activation,Intracel,Models,Exchanger,Rabbits,Red,AdenosineFerrets,Signaling,ActionHeartHydrolysis,Myocytes,Binding,Myocardium,Cardiovascular,SarcoplasmicGov't,AdrenergicTriphosphate,Kinetics,Proteins,Thapsigargin,Cardiac,Non-U.S.Inhibitors,MyocardialComputerDiastole,Phosphorylation,EnzymeAMP-DependentCultured,Heart,
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1Increased availability and open probability of single L-type calcium channels from failing compared with nonfailing human ventricle.
F. Schr�der, R. Handrock, D. Beuckelmann, S. Hirt, R. Hullin, L. Priebe, R. Schwinger, J. Weil, and S. Herzig. Circulation, 98 (10): 969--976 (September 1998)
16 years ago by @hake
show all tags
Calcium,
Failure,
Ion
Reference
l
L-Type,
Cardiomyopathies,
Humans,
Gating,
Monophosphate,
Ventricles,
Calcium
Cyclosporine,
Research
Time
Cells,
Cardiomyopathy,
Factors,
U.S.
Myocardia,
Membrane
AMP,
Muscle
Cell
Barium,
Channel
Channels,
Potentials,
Support,
Congestive,
Values,
Ischemia,
P.H.S.,
Cyclic
8-Bromo
Atria,
Line,
Adenosine
Heart
Dilated,
Gov't,
Comparative
9737516
Kinetics,
Proteins,
Non-U.S.
Study,
Probability,
Recombinant
Cultured,
Calcineurin,
Heart,
Calcium,Failure,IonReferencelL-Type,Cardiomyopathies,Humans,Gating,Monophosphate,Ventricles,CalciumCyclosporine,ResearchTimeCells,Cardiomyopathy,Factors,U.S.Myocardia,MembraneAMP,MuscleCellBarium,ChannelChannels,Potentials,Support,Congestive,Values,Ischemia,P.H.S.,Cyclic8-BromoAtria,Line,AdenosineHeartDilated,Gov't,Comparative9737516Kinetics,Proteins,Non-U.S.Study,Probability,RecombinantCultured,Calcineurin,Heart,
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1Ca$^2+$/calmodulin-dependent protein kinase modulates cardiac ryanodine receptor phosphorylation and sarcoplasmic reticulum Ca$^2+$ leak in heart failure.
X. Ai, J. Curran, T. Shannon, D. Bers, and S. Pogwizd. Circ. Res., 97 (12): 1314--1322 (December 2005)
16 years ago by @hake
show all tags
Binding
16339492
{C}a$^{2+}$-Transporting
Calcium,
Failure,
Arrhythmia,
dulin
Channels,
Support,
Echocardiography,
Congestive,
Cytoplasmic
{C}a$^{2+}$-Calmo,
Protein
Reticulum,
Receptor
Kinases,
Cyclic
ATPase,
Tacrolimus
Extramural,
Benzylamines,
1A,
Rabbits,
N.I.H.,
Animals,
K,
Ryanodine
Nuclear,
Heart
Calcium
Myocytes,
Sarcoplasmic
Calcium-Binding
Dependent
Research
Receptors,
Sulfonamides,
Proteins,
inase,
Cardiac,
Channel,
and
Phosphorylation,
AMP-Dependent
Release
Binding16339492{C}a$^{2+}$-TransportingCalcium,Failure,Arrhythmia,dulinChannels,Support,Echocardiography,Congestive,Cytoplasmic{C}a$^{2+}$-Calmo,ProteinReticulum,ReceptorKinases,CyclicATPase,TacrolimusExtramural,Benzylamines,1A,Rabbits,N.I.H.,Animals,K,RyanodineNuclear,HeartCalciumMyocytes,SarcoplasmicCalcium-BindingDependentResearchReceptors,Sulfonamides,Proteins,inase,Cardiac,Channel,andPhosphorylation,AMP-DependentRelease
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1A simplified local control model of calcium-induced calcium release in cardiac ventricular myocytes.
R. Hinch, J. Greenstein, A. Tanskanen, L. Xu, and R. Winslow. Biophys. J., 87 (6): 3723--3736 (December 2004)
16 years ago by @hake
show all tags
Biophysics,
Ion
Biological,
Ions,
Expression
Profiling,
Ryanodine
Animals,
Adaptor
Regulation,
Research
Time
Cells,
Mapping,
Kinase,
Phosphoprotein
Membrane
Relationship,
beta-1,
Release
QT
Markov
Voltage-Gated,
Interaction
Channel
Contraction,
Potentials,
Transduction,
Protein
Processes,
Extramural,
Models,
Complexes,
Potassium
Structure-Activity
Signaling,
Heart
Myocytes,
Guinea
Myocardium,
Conduction
Gene
System,
Non-U.S.
Computer
Signal
AMP-Dependent
Adrenergic,
Calcium,
Simulation,
Multiprotein
L-Type,
{C}a$^{2+}$-Calmodulin
Humans,
Proteome,
Kinases,
Gating,
Neurons,
Membrane,
Ventricles,
Long
Calcium
Dogs,
Dependent
Stochastic
Transducing,
Ryanodine,
Syndrome,
Electrophysiology,
Receptors,
Factors,
U.S.
Algorithms,
Muscle
Cell
Pigs,
Proteomics,
Channels,
Support,
P.H.S.,
Receptor
Cyclic
Isoproterenol,
Post-Translational,
Chains,
N.I.H.,
Action
Acid
Cardiovascular,
Gov't,
Comparative
Substitution,
Proteins,
Cardiac,
Channel,
Myocardial
Study,
Amino
Phosphorylation,
Phosphatase,
Processing,
Biophysics,IonBiological,Ions,ExpressionProfiling,RyanodineAnimals,AdaptorRegulation,ResearchTimeCells,Mapping,Kinase,PhosphoproteinMembraneRelationship,beta-1,ReleaseQTMarkovVoltage-Gated,InteractionChannelContraction,Potentials,Transduction,ProteinProcesses,Extramural,Models,Complexes,PotassiumStructure-ActivitySignaling,HeartMyocytes,GuineaMyocardium,ConductionGeneSystem,Non-U.S.ComputerSignalAMP-DependentAdrenergic,Calcium,Simulation,MultiproteinL-Type,{C}a$^{2+}$-CalmodulinHumans,Proteome,Kinases,Gating,Neurons,Membrane,Ventricles,LongCalciumDogs,DependentStochasticTransducing,Ryanodine,Syndrome,Electrophysiology,Receptors,Factors,U.S.Algorithms,MuscleCellPigs,Proteomics,Channels,Support,P.H.S.,ReceptorCyclicIsoproterenol,Post-Translational,Chains,N.I.H.,ActionAcidCardiovascular,Gov't,ComparativeSubstitution,Proteins,Cardiac,Channel,MyocardialStudy,AminoPhosphorylation,Phosphatase,Processing,
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1The Noether numbers for cyclic groups of prime order
P. Fleischmann, M. Sezer, R. Shank, and C. Woodcock. (August 2005)
17 years ago by @a_olympia
show all tags
prime
of
noether
for
numbers
order
groups
cyclic
primeofnoetherfornumbersordergroupscyclic
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