%0 Journal Article %1 citeulike:4545374 %A Guerquinkern, J. %A Wu, T. %A Quintana, C. %A Croisy, A. %D 2005 %J Biochimica et Biophysica Acta (BBA) - General Subjects %K nanosims, sims %N 3 %P 228--238 %R 10.1016/j.bbagen.2005.05.013 %T Progress in analytical imaging of the cell by dynamic secondary ion mass spectrometry (SIMS microscopy) %U http://dx.doi.org/10.1016/j.bbagen.2005.05.013 %V 1724 %X This paper reviews the most recent methodological advances in the field of biological imaging using dynamic secondary ion mass spectrometry (SIMS). After a short reminder of the basic principle of SIMS imaging, the latest high-resolution dynamic SIMS equipment is briefly described. This new ion nanoprobe (CAMECA NanoSIMS 50™) has a lateral resolution of less than 50 nm with primary Cs + ion, the ability to detect simultaneously 5 different ions from the same micro-volume and a very good transmission even at high mass resolution (60\% at M /Δ M  = 5000). Basic considerations related to sample preparation, mass resolution and primary ion implantation are given. The decisive capability of this new instrument, and more generally of high-resolution dynamic SIMS imaging in biology, are illustrated with the most recent examples of utilization 2 .

@article{citeulike:4545374, abstract = {This paper reviews the most recent methodological advances in the field of biological imaging using dynamic secondary ion mass spectrometry (SIMS). After a short reminder of the basic principle of SIMS imaging, the latest high-resolution dynamic SIMS equipment is briefly described. This new ion nanoprobe (CAMECA NanoSIMS 50™) has a lateral resolution of less than 50 nm with primary Cs + ion, the ability to detect simultaneously 5 different ions from the same micro-volume and a very good transmission even at high mass resolution (60\% at M /Δ M  = 5000). Basic considerations related to sample preparation, mass resolution and primary ion implantation are given. The decisive capability of this new instrument, and more generally of high-resolution dynamic SIMS imaging in biology, are illustrated with the most recent examples of utilization 2 .}, added-at = {2009-05-19T18:00:18.000+0200}, author = {Guerquinkern, J. and Wu, T. and Quintana, C. and Croisy, A.}, biburl = {https://www.bibsonomy.org/bibtex/2d7eb82a340d4bf18b91b1665b650dc6b/earthfare}, citeulike-article-id = {4545374}, description = {CiteULike: Everyone's library}, doi = {10.1016/j.bbagen.2005.05.013}, interhash = {0fd0d37d1fae3e1eacfedc7462e40832}, intrahash = {d7eb82a340d4bf18b91b1665b650dc6b}, issn = {03044165}, journal = {Biochimica et Biophysica Acta (BBA) - General Subjects}, keywords = {nanosims, sims}, month = {August}, number = 3, pages = {228--238}, posted-at = {2009-05-19 16:54:23}, priority = {3}, timestamp = {2009-05-19T18:03:27.000+0200}, title = {Progress in analytical imaging of the cell by dynamic secondary ion mass spectrometry (SIMS microscopy)}, url = {http://dx.doi.org/10.1016/j.bbagen.2005.05.013}, volume = 1724, year = 2005 }