%0 Journal Article %1 citeulike:7801725 %A Calderón, Andrés J. %A Heo, Yun S. %A Huh, Dongeun %A Futai, Nobuyuki %A Takayama, Shuichi %A Fowlkes, J. Brian %A Bull, Joseph L. %D 2006 %J Applied Physics Letters %K 76t10-liquid-gas-two-phase-flows-bubbly-flows 76b45-capillarity %N 24 %P 244103+ %T Microfluidic Model of Bubble Lodging in Microvessel Bifurcations %U http://apl.aip.org/resource/1/applab/v89/i24/p244103\_s1?isAuthorized=no %V 89 %X The lodging mechanisms and dynamics of cardiovascular gas bubbles are investigated in microfluidic model bifurcations made of poly(dimethylsiloxane). This work is motivated by gas embolotherapy for the potential treatment of cancer by tumor infarction. The results show that the critical driving pressure below which a bubble will lodge in a bifurcation is significantly less than the driving pressure required to dislodge it. From the results the authors estimate that gas bubbles from embolotherapy can lodge in vessels 20 μm or smaller in diameter, and conclude that bubbles may potentially be used to reduce blood flow to tumor microcirculation.

@article{citeulike:7801725, abstract = {{The lodging mechanisms and dynamics of cardiovascular gas bubbles are investigated in microfluidic model bifurcations made of poly(dimethylsiloxane). This work is motivated by gas embolotherapy for the potential treatment of cancer by tumor infarction. The results show that the critical driving pressure below which a bubble will lodge in a bifurcation is significantly less than the driving pressure required to dislodge it. From the results the authors estimate that gas bubbles from embolotherapy can lodge in vessels 20 μm or smaller in diameter, and conclude that bubbles may potentially be used to reduce blood flow to tumor microcirculation.}}, added-at = {2017-06-29T07:13:07.000+0200}, author = {Calder\'{o}n, Andr\'{e}s J. and Heo, Yun S. and Huh, Dongeun and Futai, Nobuyuki and Takayama, Shuichi and Fowlkes, J. Brian and Bull, Joseph L.}, biburl = {https://www.bibsonomy.org/bibtex/2dee83101ffb97932e1323bd1e22d8255/gdmcbain}, citeulike-article-id = {7801725}, citeulike-attachment-1 = {calderon_et_al_APL_2006.pdf; /pdf/user/gdmcbain/article/7801725/540803/calderon_et_al_APL_2006.pdf; 50a0b8dcb8c4c7e54434cc4987a31e94df302f04}, citeulike-linkout-0 = {http://apl.aip.org/resource/1/applab/v89/i24/p244103\_s1?isAuthorized=no}, comment = {(private-note)circulated by SGM 2010-09-09}, file = {calderon_et_al_APL_2006.pdf}, interhash = {084a329a10357fdca6559c6729d7602a}, intrahash = {dee83101ffb97932e1323bd1e22d8255}, journal = {Applied Physics Letters}, keywords = {76t10-liquid-gas-two-phase-flows-bubbly-flows 76b45-capillarity}, number = 24, pages = {244103+}, posted-at = {2010-09-09 03:04:21}, priority = {2}, timestamp = {2019-02-28T23:44:17.000+0100}, title = {{Microfluidic Model of Bubble Lodging in Microvessel Bifurcations}}, url = {http://apl.aip.org/resource/1/applab/v89/i24/p244103\_s1?isAuthorized=no}, volume = 89, year = 2006 }