Abstract
The Suzuki-Miyaura reaction of various aryl halides with aryl boronic
acids using \Ph2PCH2PPh2CH=C(O)(C10H7)PdCl2\ as a catalyst has
been investigated. The X-ray crystal structure of the catalyst reveals a
five-membered chelate ring formed by coordination of the ligand through
the phosphine group and the ylidic carbon atom to the metal center. This
palladacycle exhibited excellent activities and reusability in the
aqueous phase for the Suzuki cross-coupling reactions of arylboronic
acids with aryl halides. The proposed protocol featured mild reaction
conditions and notable simplicity and efficiency using Cs2CO3 as a base
in water. The catalytic system could be reused four times without
significant loss of activity.
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