Botulinum toxin type a injections to salivary glands: combination with single event multilevel chemoneurolysis in 2 children with severe spastic quadriplegic cerebral palsy.
We describe 2 children with severe spastic quadriplegic cerebral palsy (CP) who have significant drooling and frequent aspiration pneumonia. They underwent simultaneous botulinum toxin type A (BTX-A) injections to salivary glands for drooling and prevention of aspiration pneumonia along with single-event multilevel chemoneurolysis (SEMLC) with BTX-A and 5\% phenol for severe diffuse spasticity. There was significant improvement in drooling, frequency of aspiration pneumonia, and spasticity without adverse effect. BTX-A injections into the salivary glands, in addition to SEMLC, for these 2 children with medically complicated severe spastic quadriplegic CP, were safe and highly successful procedures, which improved their health-related quality of life.
%0 Journal Article
%1 Kim2006
%A Kim, Heakyung
%A Lee, Yung
%A Weiner, Daniel
%A Kaye, Robin
%A Cahill, Anne Marie
%A Yudkoff, Marc
%D 2006
%J Arch Phys Med Rehabil
%K Botulinum Toxin Type A; Cerebral Palsy; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Muscle Spasticity; Neuromuscular Agents; Blockade; Pneumonia, Aspiration; Quadriplegia; Risk Assessment; Salivary Glands; Salivation; Severity of Illness Index; Treatment Outcome
%N 1
%P 141--144
%R 10.1016/j.apmr.2005.08.112
%T Botulinum toxin type a injections to salivary glands: combination with single event multilevel chemoneurolysis in 2 children with severe spastic quadriplegic cerebral palsy.
%U http://dx.doi.org/10.1016/j.apmr.2005.08.112
%V 87
%X We describe 2 children with severe spastic quadriplegic cerebral palsy (CP) who have significant drooling and frequent aspiration pneumonia. They underwent simultaneous botulinum toxin type A (BTX-A) injections to salivary glands for drooling and prevention of aspiration pneumonia along with single-event multilevel chemoneurolysis (SEMLC) with BTX-A and 5\% phenol for severe diffuse spasticity. There was significant improvement in drooling, frequency of aspiration pneumonia, and spasticity without adverse effect. BTX-A injections into the salivary glands, in addition to SEMLC, for these 2 children with medically complicated severe spastic quadriplegic CP, were safe and highly successful procedures, which improved their health-related quality of life.
@article{Kim2006,
abstract = {We describe 2 children with severe spastic quadriplegic cerebral palsy (CP) who have significant drooling and frequent aspiration pneumonia. They underwent simultaneous botulinum toxin type A (BTX-A) injections to salivary glands for drooling and prevention of aspiration pneumonia along with single-event multilevel chemoneurolysis (SEMLC) with BTX-A and 5\% phenol for severe diffuse spasticity. There was significant improvement in drooling, frequency of aspiration pneumonia, and spasticity without adverse effect. BTX-A injections into the salivary glands, in addition to SEMLC, for these 2 children with medically complicated severe spastic quadriplegic CP, were safe and highly successful procedures, which improved their health-related quality of life.},
added-at = {2014-07-19T20:37:49.000+0200},
author = {Kim, Heakyung and Lee, Yung and Weiner, Daniel and Kaye, Robin and Cahill, Anne Marie and Yudkoff, Marc},
biburl = {https://www.bibsonomy.org/bibtex/2d27aa90a1c90cb77d8a3913581cf5849/ar0berts},
doi = {10.1016/j.apmr.2005.08.112},
groups = {public},
interhash = {1d745666668af93a52c82dae51d36708},
intrahash = {d27aa90a1c90cb77d8a3913581cf5849},
journal = {Arch Phys Med Rehabil},
keywords = {Botulinum Toxin Type A; Cerebral Palsy; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Muscle Spasticity; Neuromuscular Agents; Blockade; Pneumonia, Aspiration; Quadriplegia; Risk Assessment; Salivary Glands; Salivation; Severity of Illness Index; Treatment Outcome},
month = Jan,
number = 1,
pages = {141--144},
pii = {S0003-9993(05)01145-7},
pmid = {16401453},
timestamp = {2014-07-19T20:37:49.000+0200},
title = {Botulinum toxin type a injections to salivary glands: combination with single event multilevel chemoneurolysis in 2 children with severe spastic quadriplegic cerebral palsy.},
url = {http://dx.doi.org/10.1016/j.apmr.2005.08.112},
username = {ar0berts},
volume = 87,
year = 2006
}