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Proteinuria reduction and progression to renal failure in patients with type 2 diabetes mellitus and overt nephropathy.

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American journal of kidney diseases : the official journal of the National Kidney Foundation, (xx Feb 2005)

Аннотация

RCT -- Baseline proteinuria is an important risk factor for kidney failure and provides a means to identify patients at greatest risk. Halving proteinuria halves the kidney risk. Proteinuria reduction using an angiotensin receptor-blocking agent, such as irbesartan, should be regarded as an important therapeutic goal in renoprotective strategies.

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