Abstract
The basic working principle of molecular motors is cyclic conformational change. In vivo the cyclic change of a generic motor is powered by ATP. However it also can be driven by an external electric AC field in the case of Na,K-ATPase. This enables us to investigate how this molecular motor will response to an oscillating energy source, including the optimum driving frequencies and amplitudes of a signal, stochastic resonance under noise, and the asymmetry factor in the kinetic equation of the motor which leads to unidirectional ion transport. The results extracted from Na, K-ATPase help us understand the fundamental properties how energy transduction can be manipulated in nanoscale machines.
Reference: C.-H. Chang and T.Y. Tsong, Phys. Rev. E 69, 021914, 2004.
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