%0 Journal Article %1 citeulike:2477027 %A Uauy, Cristobal %A Distelfeld, Assaf %A Fahima, Tzion %A Blechl, Ann %A Dubcovsky, Jorge %D 2006 %I American Association for the Advancement of Science %J Science %K biochemistry, breeding, citeulikeExport nutrient, senescence %N 5803 %P 1298--1301 %R 10.1126/science.1133649 %T A NAC Gene Regulating Senescence Improves Grain Protein, Zinc, and Iron Content in Wheat %U http://dx.doi.org/10.1126/science.1133649 %V 314 %X Enhancing the nutritional value of food crops is a means of improving human nutrition and health. We report here the positional cloning of Gpc-B1, a wheat quantitative trait locus associated with increased grain protein, zinc, and iron content. The ancestral wild wheat allele encodes a NAC transcription factor (NAM-B1) that accelerates senescence and increases nutrient remobilization from leaves to developing grains, whereas modern wheat varieties carry a nonfunctional NAM-B1 allele. Reduction in RNA levels of the multiple NAM homologs by RNA interference delayed senescence by more than 3 weeks and reduced wheat grain protein, zinc, and iron content by more than 30\%.

@article{citeulike:2477027, abstract = {{Enhancing the nutritional value of food crops is a means of improving human nutrition and health. We report here the positional cloning of Gpc-B1, a wheat quantitative trait locus associated with increased grain protein, zinc, and iron content. The ancestral wild wheat allele encodes a NAC transcription factor (NAM-B1) that accelerates senescence and increases nutrient remobilization from leaves to developing grains, whereas modern wheat varieties carry a nonfunctional NAM-B1 allele. Reduction in RNA levels of the multiple NAM homologs by RNA interference delayed senescence by more than 3 weeks and reduced wheat grain protein, zinc, and iron content by more than 30\%.}}, added-at = {2019-03-31T01:14:40.000+0100}, author = {Uauy, Cristobal and Distelfeld, Assaf and Fahima, Tzion and Blechl, Ann and Dubcovsky, Jorge}, biburl = {https://www.bibsonomy.org/bibtex/249db74b9271f3226f4424817627b6dad/dianella}, citeulike-article-id = {2477027}, citeulike-linkout-0 = {http://dx.doi.org/10.1126/science.1133649}, citeulike-linkout-1 = {http://www.sciencemag.org/content/314/5803/1298.abstract}, citeulike-linkout-2 = {http://www.sciencemag.org/content/314/5803/1298.full.pdf}, citeulike-linkout-3 = {http://www.sciencemag.org/cgi/content/abstract/314/5803/1298}, citeulike-linkout-4 = {http://view.ncbi.nlm.nih.gov/pubmed/17124321}, citeulike-linkout-5 = {http://www.hubmed.org/display.cgi?uids=17124321}, day = 24, doi = {10.1126/science.1133649}, interhash = {5afef9e4a58f2664384b955cf42f511d}, intrahash = {49db74b9271f3226f4424817627b6dad}, issn = {1095-9203}, journal = {Science}, keywords = {biochemistry, breeding, citeulikeExport nutrient, senescence}, month = nov, number = 5803, pages = {1298--1301}, pmid = {17124321}, posted-at = {2014-03-21 16:04:51}, priority = {2}, publisher = {American Association for the Advancement of Science}, timestamp = {2019-03-31T01:16:26.000+0100}, title = {{A NAC Gene Regulating Senescence Improves Grain Protein, Zinc, and Iron Content in Wheat}}, url = {http://dx.doi.org/10.1126/science.1133649}, volume = 314, year = 2006 }