%0 Journal Article %1 tsubone2020vitro %A Tsubone, Tayana Mazin %A de Sousa Rocha, Cleidiane %A Tonolli, Paulo Newton %A II-Sei, Watanabe %A Stolf, Beatriz Simonsen %A Baptista, Maurício S. %A Martins, Waleska Kerllen %D 2020 %J Advances in Biochemistry and Biotechnology %K Aging Autophagy Chloroquine Cytotoxicity Long-term response %N 1 %P 15 %T In vitro Autophagy Modulation with Chloroquine: Some Lessons to Learn %U https://www.gavinpublishers.com/article/view/in-vitro-autophagy-modulation-with-chloroquine-some-lessons-to-learn %V 5 %X CQ cytotoxicity is related to lysosomal impairment that leads to autophagy-associated cell death, nuclei abnormalities, lipofuscinogenesis, and senescence. Also, our findings indicate that a therapeutic approach based on lysosomal chemo-sensitization triggered by CQ parallel to mitochondrial OA-toxicity may represent a promisor strategy to overcome in vivo tumor progression relied on apoptosis lessening.

@article{tsubone2020vitro, abstract = {CQ cytotoxicity is related to lysosomal impairment that leads to autophagy-associated cell death, nuclei abnormalities, lipofuscinogenesis, and senescence. Also, our findings indicate that a therapeutic approach based on lysosomal chemo-sensitization triggered by CQ parallel to mitochondrial OA-toxicity may represent a promisor strategy to overcome in vivo tumor progression relied on apoptosis lessening.}, added-at = {2020-02-26T06:19:25.000+0100}, author = {Tsubone, Tayana Mazin and de Sousa Rocha, Cleidiane and Tonolli, Paulo Newton and II-Sei, Watanabe and Stolf, Beatriz Simonsen and Baptista, Maurício S. and Martins, Waleska Kerllen}, biburl = {https://www.bibsonomy.org/bibtex/2ecf29f7fab399bd992fd38ac70a00d40/alyssacarter}, interhash = {167787dd6a855bdd3d1576556801e73e}, intrahash = {ecf29f7fab399bd992fd38ac70a00d40}, issn = {2574-7258}, journal = {Advances in Biochemistry and Biotechnology}, keywords = {Aging Autophagy Chloroquine Cytotoxicity Long-term response}, language = {English}, month = {February}, number = 1, pages = 15, timestamp = {2021-10-09T12:44:53.000+0200}, title = {In vitro Autophagy Modulation with Chloroquine: Some Lessons to Learn}, url = {https://www.gavinpublishers.com/article/view/in-vitro-autophagy-modulation-with-chloroquine-some-lessons-to-learn}, volume = 5, year = 2020 }