%0 Journal Article %1 WOS:000515200700054 %A Nascimento, Kyria Santiago %A Silva, Mayara Torquato Lima %A Oliveira, Messias Vital %A Lossio, Claudia Figueiredo %A Pinto-Junior, Vanir Reis %A Osterne, Vinicius Jose Silva %A Cavada, Benildo Sousa %C RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS %D 2020 %I ELSEVIER %J INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES %K Dalbergieae Leguminosae; tribe} {Lectins; %P 509-526 %R 10.1016/j.ijbiomac.2019.12.117 %T Dalbergieae lectins: A review of lectins from species of a primitive Papilionoideae (leguminous) tribe %V 144 %X Lectins are (glyco)proteins capable of reversibly binding to specific carbohydrates, thus having various functions and applications. Plant lectins are the best studied, and the Leguminoseae family is highlighted in a number of published works, especially species of the Papilionoideae subfamily. Dalbergieae is one of the tribes in this subfamily comprising 49 genera and over 1300 species. From this tribe, about 26 lectins were studied, among which we can highlight the Arachis hypogaea lectin, widely used in cancer studies. Dalbergieae lectins demonstrate various carbohydrate specificities and biological activities including anti-inflammatory, vasorelaxant, nociceptive, antibacterial, antiviral among others. Structurally, these lectins are quite similar in their three-dimensional folding but present significant differences in oligomerization patterns and in the conservation of carbohydrate-recognition domain. Despite the existence of structural data from some lectins, only sparse literature has reported on this tribe's diversity, not to mention the range of biological effects, determined through specific assays. Therefore, this work will review the most important studies on Dalbergieae lectins and their potential biomedical applications. (C) 2018 Published by Elsevier B.V.

@article{WOS:000515200700054, abstract = {Lectins are (glyco)proteins capable of reversibly binding to specific carbohydrates, thus having various functions and applications. Plant lectins are the best studied, and the Leguminoseae family is highlighted in a number of published works, especially species of the Papilionoideae subfamily. Dalbergieae is one of the tribes in this subfamily comprising 49 genera and over 1300 species. From this tribe, about 26 lectins were studied, among which we can highlight the Arachis hypogaea lectin, widely used in cancer studies. Dalbergieae lectins demonstrate various carbohydrate specificities and biological activities including anti-inflammatory, vasorelaxant, nociceptive, antibacterial, antiviral among others. Structurally, these lectins are quite similar in their three-dimensional folding but present significant differences in oligomerization patterns and in the conservation of carbohydrate-recognition domain. Despite the existence of structural data from some lectins, only sparse literature has reported on this tribe's diversity, not to mention the range of biological effects, determined through specific assays. Therefore, this work will review the most important studies on Dalbergieae lectins and their potential biomedical applications. (C) 2018 Published by Elsevier B.V.}, added-at = {2022-05-23T20:00:14.000+0200}, address = {RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS}, author = {Nascimento, Kyria Santiago and Silva, Mayara Torquato Lima and Oliveira, Messias Vital and Lossio, Claudia Figueiredo and Pinto-Junior, Vanir Reis and Osterne, Vinicius Jose Silva and Cavada, Benildo Sousa}, biburl = {https://www.bibsonomy.org/bibtex/2354ffab3481d706ded6fb03469537378/ppgfis_ufc_br}, doi = {10.1016/j.ijbiomac.2019.12.117}, interhash = {74ab6adbde1d3c61f08abb37706e53c4}, intrahash = {354ffab3481d706ded6fb03469537378}, issn = {0141-8130}, journal = {INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES}, keywords = {Dalbergieae Leguminosae; tribe} {Lectins;}, pages = {509-526}, publisher = {ELSEVIER}, pubstate = {published}, timestamp = {2022-05-23T20:00:14.000+0200}, title = {Dalbergieae lectins: A review of lectins from species of a primitive Papilionoideae (leguminous) tribe}, tppubtype = {article}, volume = 144, year = 2020 }