%0 Journal Article %1 Ek1998 %A Ek, U. %A Fernell, E. %A Jacobson, L. %A Gillberg, C. %D 1998 %J Dev Med Child Neurol %K Adolescent; Autistic Disorder; Blindness; Brain; Cerebral Palsy; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Premature; Male; Mental Retardation; Retinopathy of Prematurity; Retrospective Single-Blind Method; Sweden %N 5 %P 297--301 %T Relation between blindness due to retinopathy of prematurity and autistic spectrum disorders: a population-based study. %V 40 %X Children with blindness due to retinopathy of prematurity (ROP)--who are at greatly increased risk of cerebral damage--have been noted to have a high rate of autistic symptoms, but systematic controlled studies have been lacking. A controlled population-based study was performed; one group was blind due to ROP (N=27) and the other was congenitally blind due to hereditary retinal disease (N=14). Fifteen of the 27 children with ROP had autistic disorder. All these children were mentally retarded and about one-third of them had cerebral palsy. In the comparison group, two of the 14 children had autistic disorder. It is concluded that there is a strong association between ROP and autistic disorder. The association is most probably mediated by brain damage and is largely independent of the blindness per se.

@article{Ek1998, abstract = {Children with blindness due to retinopathy of prematurity (ROP)--who are at greatly increased risk of cerebral damage--have been noted to have a high rate of autistic symptoms, but systematic controlled studies have been lacking. A controlled population-based study was performed; one group was blind due to ROP (N=27) and the other was congenitally blind due to hereditary retinal disease (N=14). Fifteen of the 27 children with ROP had autistic disorder. All these children were mentally retarded and about one-third of them had cerebral palsy. In the comparison group, two of the 14 children had autistic disorder. It is concluded that there is a strong association between ROP and autistic disorder. The association is most probably mediated by brain damage and is largely independent of the blindness per se.}, added-at = {2014-07-19T19:24:27.000+0200}, author = {Ek, U. and Fernell, E. and Jacobson, L. and Gillberg, C.}, biburl = {https://www.bibsonomy.org/bibtex/2a01ab863bdaad009a4e7532622af0091/ar0berts}, groups = {public}, interhash = {9e1e66b0a54c224b06a5bb530c50c709}, intrahash = {a01ab863bdaad009a4e7532622af0091}, journal = {Dev Med Child Neurol}, keywords = {Adolescent; Autistic Disorder; Blindness; Brain; Cerebral Palsy; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Premature; Male; Mental Retardation; Retinopathy of Prematurity; Retrospective Single-Blind Method; Sweden}, month = May, number = 5, pages = {297--301}, pmid = {9630256}, timestamp = {2014-07-19T19:24:27.000+0200}, title = {Relation between blindness due to retinopathy of prematurity and autistic spectrum disorders: a population-based study.}, username = {ar0berts}, volume = 40, year = 1998 }