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Absorption of tungsten carbonyl anions into the lipid bilayer membrane of mouse myeloma cells
INORGANIC CHEMISTRY, 35 (20): 5762-& (сентября 1996)
Аннотация
The anions of the tungsten carbonyl salts NaW(CO)(5)(CN). 3H2(O) (1), KW(CO)(5)(NCS) (2), and KW-2(CO)(10)(mu-SCN) (3) are readily taken up by the lipid membrane of living cells. Cell rotation experiments show that at solution concentrations in the micromolar range the lipid bilayer absorbs up to 1.0 pmol cm(-2) of these anions, which leads to a pronounced increase of both the conductance, G(m), and the capacitance, C-m, of the membrane. 1-3 and similar salts are thus seen as ideal instruments to further develop models of mass transport through lipid membranes.
