%0 Journal Article %1 lazaridis2013ancient %A Lazaridis, Iosif %A Patterson, Nick %A Mittnik, Alissa %A Renaud, Gabriel %A Mallick, Swapan %A Sudmant, Peter H. %A Schraiber, Joshua G. %A Castellano, Sergi %A Kirsanow, Karola %A Economou, Christos %A Bollongino, Ruth %A Fu, Qiaomei %A Bos, Kirsten %A Nordenfelt, Susanne %A de Filippo, Cesare %A Prüfer, Kay %A Sawyer, Susanna %A Posth, Cosimo %A Haak, Wolfgang %A Hallgren, Fredrik %A Fornander, Elin %A Ayodo, George %A Babiker, Hamza A. %A Balanovska, Elena %A Balanovsky, Oleg %A Ben-Ami, Haim %A Bene, Judit %A Berrada, Fouad %A Brisighelli, Francesca %A Busby, George B.J. %A Cali, Francesco %A Churnosov, Mikhail %A Cole, David E.C. %A Damba, Larissa %A Delsate, Dominique %A van Driem, George %A Dryomov, Stanislav %A Fedorova, Sardana A. %A Francken, Michael %A Romero, Irene Gallego %A Gubina, Marina %A Guinet, Jean-Michel %A Hammer, Michael %A Henn, Brenna %A Helvig, Tor %A Hodoglugil, Ugur %A Jha, Aashish R. %A Kittles, Rick %A Khusnutdinova, Elza %A Kivisild, Toomas %A Kučinskas, Vaidutis %A Khusainova, Rita %A Kushniarevich, Alena %A Laredj, Leila %A Litvinov, Sergey %A Mahley, Robert W. %A Melegh, Béla %A Metspalu, Ene %A Mountain, Joanna %A Nyambo, Thomas %A Osipova, Ludmila %A Parik, Jüri %A Platonov, Fedor %A Posukh, Olga L. %A Romano, Valentino %A Rudan, Igor %A Ruizbakiev, Ruslan %A Sahakyan, Hovhannes %A Salas, Antonio %A Starikovskaya, Elena B. %A Tarekegn, Ayele %A Toncheva, Draga %A Turdikulova, Shahlo %A Uktveryte, Ingrida %A Utevska, Olga %A Voevoda, Mikhail %A Wahl, Joachim %A Zalloua, Pierre %A Yepiskoposyan, Levon %A Zemunik, Tatijana %A Cooper, Alan %A Capelli, Cristian %A Thomas, Mark G. %A Tishkoff, Sarah A. %A Singh, Lalji %A Thangaraj, Kumarasamy %A Villems, Richard %A Comas, David %A Sukernik, Rem %A Metspalu, Mait %A Meyer, Matthias %A Eichler, Evan E. %A Burger, Joachim %A Slatkin, Montgomery %A Pääbo, Svante %A Kelso, Janet %A Reich, David %A Krause, Johannes %D 2013 %K ancient_DNA eurogenetics %T Ancient human genomes suggest three ancestral populations for present-day Europeans %U http://biorxiv.org/content/early/2013/12/23/001552 %X Analysis of ancient DNA can reveal historical events that are difficult to discern through study of present-day individuals. To investigate European population history around the time of the agricultural transition, we sequenced complete genomes from a ~7,500 year old early farmer from the Linearbandkeramik (LBK) culture from Stuttgart in Germany and an ~8,000 year old hunter-gatherer from the Loschbour rock shelter in Luxembourg. We also generated data from seven ~8,000 year old hunter-gatherers from Motala in Sweden. We compared these genomes and published ancient DNA to new data from 2,196 samples from 185 diverse populations to show that at least three ancestral groups contributed to present-day Europeans. The first are Ancient North Eurasians (ANE), who are more closely related to Upper Paleolithic Siberians than to any present-day population. The second are West European Hunter-Gatherers (WHG), related to the Loschbour individual, who contributed to all Europeans but not to Near Easterners. The third are Early European Farmers (EEF), related to the Stuttgart individual, who were mainly of Near Eastern origin but also harbored WHG-related ancestry. We model the deep relationships of these populations and show that about 44\% of the ancestry of EEF derived from a basal Eurasian lineage that split prior to the separation of other non-Africans.

@article{lazaridis2013ancient, abstract = {Analysis of ancient DNA can reveal historical events that are difficult to discern through study of present-day individuals. To investigate European population history around the time of the agricultural transition, we sequenced complete genomes from a ~7,500 year old early farmer from the Linearbandkeramik (LBK) culture from Stuttgart in Germany and an ~8,000 year old hunter-gatherer from the Loschbour rock shelter in Luxembourg. We also generated data from seven ~8,000 year old hunter-gatherers from Motala in Sweden. We compared these genomes and published ancient DNA to new data from 2,196 samples from 185 diverse populations to show that at least three ancestral groups contributed to present-day Europeans. The first are Ancient North Eurasians (ANE), who are more closely related to Upper Paleolithic Siberians than to any present-day population. The second are West European Hunter-Gatherers (WHG), related to the Loschbour individual, who contributed to all Europeans but not to Near Easterners. The third are Early European Farmers (EEF), related to the Stuttgart individual, who were mainly of Near Eastern origin but also harbored WHG-related ancestry. We model the deep relationships of these populations and show that about 44\% of the ancestry of EEF derived from a basal Eurasian lineage that split prior to the separation of other non-Africans.}, added-at = {2014-01-07T09:31:40.000+0100}, author = {Lazaridis, Iosif and Patterson, Nick and Mittnik, Alissa and Renaud, Gabriel and Mallick, Swapan and Sudmant, Peter H. and Schraiber, Joshua G. and Castellano, Sergi and Kirsanow, Karola and Economou, Christos and Bollongino, Ruth and Fu, Qiaomei and Bos, Kirsten and Nordenfelt, Susanne and de Filippo, Cesare and Prüfer, Kay and Sawyer, Susanna and Posth, Cosimo and Haak, Wolfgang and Hallgren, Fredrik and Fornander, Elin and Ayodo, George and Babiker, Hamza A. and Balanovska, Elena and Balanovsky, Oleg and Ben-Ami, Haim and Bene, Judit and Berrada, Fouad and Brisighelli, Francesca and Busby, George B.J. and Cali, Francesco and Churnosov, Mikhail and Cole, David E.C. and Damba, Larissa and Delsate, Dominique and van Driem, George and Dryomov, Stanislav and Fedorova, Sardana A. and Francken, Michael and Romero, Irene Gallego and Gubina, Marina and Guinet, Jean-Michel and Hammer, Michael and Henn, Brenna and Helvig, Tor and Hodoglugil, Ugur and Jha, Aashish R. and Kittles, Rick and Khusnutdinova, Elza and Kivisild, Toomas and Kučinskas, Vaidutis and Khusainova, Rita and Kushniarevich, Alena and Laredj, Leila and Litvinov, Sergey and Mahley, Robert W. and Melegh, Béla and Metspalu, Ene and Mountain, Joanna and Nyambo, Thomas and Osipova, Ludmila and Parik, Jüri and Platonov, Fedor and Posukh, Olga L. and Romano, Valentino and Rudan, Igor and Ruizbakiev, Ruslan and Sahakyan, Hovhannes and Salas, Antonio and Starikovskaya, Elena B. and Tarekegn, Ayele and Toncheva, Draga and Turdikulova, Shahlo and Uktveryte, Ingrida and Utevska, Olga and Voevoda, Mikhail and Wahl, Joachim and Zalloua, Pierre and Yepiskoposyan, Levon and Zemunik, Tatijana and Cooper, Alan and Capelli, Cristian and Thomas, Mark G. and Tishkoff, Sarah A. and Singh, Lalji and Thangaraj, Kumarasamy and Villems, Richard and Comas, David and Sukernik, Rem and Metspalu, Mait and Meyer, Matthias and Eichler, Evan E. and Burger, Joachim and Slatkin, Montgomery and Pääbo, Svante and Kelso, Janet and Reich, David and Krause, Johannes}, biburl = {https://www.bibsonomy.org/bibtex/25a8638a8e09af3778727a5a9e7df6f39/peter.ralph}, interhash = {a560e7221f6ddc54d423abde65e68299}, intrahash = {5a8638a8e09af3778727a5a9e7df6f39}, keywords = {ancient_DNA eurogenetics}, timestamp = {2014-01-07T09:31:40.000+0100}, title = {Ancient human genomes suggest three ancestral populations for present-day Europeans}, url = {http://biorxiv.org/content/early/2013/12/23/001552}, year = 2013 }