%0 Journal Article %1 Flight2015 %A Flight, Laura %A Julious, Steven A %D 2015 %J Pharmaceutical statistics %K clinicaltrials equivalence non-inferiority power samplesize %N 1 %P 80-9 %R 10.1002/pst.1716 %T Practical guide to sample size calculations: non-inferiority and equivalence trials. %U http://www.ncbi.nlm.nih.gov/pubmed/26604186 %V 15 %X A sample size justification is a vital part of any trial design. However, estimating the number of participants required to give a meaningful result is not always straightforward. A number of components are required to facilitate a suitable sample size calculation. In this paper, the steps for conducting sample size calculations for non-inferiority and equivalence trials are summarised. Practical advice and examples are provided that illustrate how to carry out the calculations by hand and using the app SampSize.

@article{Flight2015, abstract = {A sample size justification is a vital part of any trial design. However, estimating the number of participants required to give a meaningful result is not always straightforward. A number of components are required to facilitate a suitable sample size calculation. In this paper, the steps for conducting sample size calculations for non-inferiority and equivalence trials are summarised. Practical advice and examples are provided that illustrate how to carry out the calculations by hand and using the app SampSize.}, added-at = {2023-02-03T11:44:35.000+0100}, author = {Flight, Laura and Julious, Steven A}, biburl = {https://www.bibsonomy.org/bibtex/2a4dcb30293a3b2970ca3f0faf0ea744c/jepcastel}, doi = {10.1002/pst.1716}, interhash = {b099419db872fa41a672458439118d6a}, intrahash = {a4dcb30293a3b2970ca3f0faf0ea744c}, issn = {1539-1612}, journal = {Pharmaceutical statistics}, keywords = {clinicaltrials equivalence non-inferiority power samplesize}, month = {11}, note = {Sample size; Tests d'equivalència}, number = 1, pages = {80-9}, pmid = {26604186}, timestamp = {2023-02-03T11:44:35.000+0100}, title = {Practical guide to sample size calculations: non-inferiority and equivalence trials.}, url = {http://www.ncbi.nlm.nih.gov/pubmed/26604186}, volume = 15, year = 2015 }