Durchmesserbestimmung von Netzhautgefäßabschnitten in digitalen Fundusfotografien - Eine klinische Studie zur Methodik und Reproduzierbarkeit: Measurement of the diameter of segments of retinal branch vessels in digital fundus images - An experimental study of the method and reproducibility
Klinische Monatsblätter für Augenheilkunde, 218 (9):
616--620 (2001)DOI: 10.1055/s-2001-17640
Аннотация
PURPOSE: The aim of this study was the evaluation of new algorithms to measure
diameter of segments of retinal branch vessels offline in local dependence and
independent by observer. Methods 360 flashed fundus images (camera FF 450 ZEISS
Germany, Visualis IMEDOS GmbH Weimar/Germany) of 12 eyes of healthy volunteers
(10 independent sessions containing 3 images for every eye) were analysed.
Algorithms detect the vessel diameter along the vessel course automatically.
Corresponding segments of a retinal artery and vein were examined (mean length of
the segment 2.5 mm) in every image of one eye. Results The marked arterial
segment was detected automatically in 359 pictures and the venous segment in all
pictures. The mean vessel diameter was detected in single pictures with a mean
coefficient of variation (CV) for arteries of 3.4 \% and for veins of 2.7 \%. The
differences of arterial and venous diameter between images were not significant.
Analyzing sessions the CV of the mean vessel diameter were reduced for arteries
to 2.7 \% and for veins to 2.5 \%. The standard deviation of the mean vessel
diameter was independent of the vessel diameter (branch vessels with diameter of
120 to 200 micrometer). The mean CV of the vessel diameter at single locations
were 5.7 \% for arteries and 3.8 \% for veins. Conclusions The new algorithms are
useful for retinal vessel analysis, if there are no questions concerning the
dynamic of vessel behaviour.