%0 Journal Article %1 Soros2001ye %A Sörös, P %A Knecht, S %A Bantel, C %A Imai, T %A Wüsten, R %A Pantev, C %A Lütkenhöner, B %A Bürkle, H %A Henningsen, H %D 2001 %J Neurosci Lett %K Cortex/*physiology induced Evoked Acute Neuronal Disease neuroscience Potentials, Non-U.S. Support, Pain/chemically Adult Somatosensory Male Gov't AND Hand Fibers/physiology Magnetoencephalography Research Humans Nerve Nociceptors/physiology Somatosensory/physiology Capsaicin Plasticity/*physiology %N 3 %P 195-8 %T Functional reorganization of the human primary somatosensory cortex after acute pain demonstrated by magnetoencephalography. %V 298 %X The somatosensory system is capable of functional reorganization following peripheral denervation or training. Studies on human amputees with phantom limb pain provided evidence that these reorganizational changes are modulated through nociceptive input. In the present study we used magnetoencephalographic recordings of six healthy volunteers to assess whether acute pain by itself causes a reorganization of the primary somatosensory cortex. After the induction of an intense experimental pain at the thenar of the left hand by intradermal injection of capsaicin, the extent of the cortical hand representation and the distance between the hand representation and the localization of the lip decreased. A likely mechanism for this acute reorganization is that pain induced hyperresponsiveness of the left thenar to tactile input from neighboring body sites.

@article{Soros2001ye, abstract = {The somatosensory system is capable of functional reorganization following peripheral denervation or training. Studies on human amputees with phantom limb pain provided evidence that these reorganizational changes are modulated through nociceptive input. In the present study we used magnetoencephalographic recordings of six healthy volunteers to assess whether acute pain by itself causes a reorganization of the primary somatosensory cortex. After the induction of an intense experimental pain at the thenar of the left hand by intradermal injection of capsaicin, the extent of the cortical hand representation and the distance between the hand representation and the localization of the lip decreased. A likely mechanism for this acute reorganization is that pain induced hyperresponsiveness of the left thenar to tactile input from neighboring body sites.}, added-at = {2006-05-30T01:06:19.000+0200}, affiliation = {Department of Neurology, University of M{\"u}nster, Albert Schweitzer-Strasse 33, 48129, M{\"u}nster, Germany. soros@uni-muenster.de}, au = {S{\"o}r{\"o}s, P}, author = {S{\"o}r{\"o}s, P and Knecht, S and Bantel, C and Imai, T and W{\"u}sten, R and Pantev, C and L{\"u}tkenh{\"o}ner, B and B{\"u}rkle, H and Henningsen, H}, biburl = {https://www.bibsonomy.org/bibtex/28ab6c0209c36359c47ab79b6c6916b57/asterix}, da = {20010222}, date-added = {2006-05-29 18:55:19 -0400}, date-modified = {2006-05-29 18:55:19 -0400}, dcom = {20010419}, description = {neuroscience literature}, edat = {2001/02/13 11:00}, interhash = {cae8dce418411dbe584dae72365a0686}, intrahash = {8ab6c0209c36359c47ab79b6c6916b57}, issn = {0304-3940}, jid = {7600130}, journal = {Neurosci Lett}, keywords = {Cortex/*physiology induced Evoked Acute Neuronal Disease neuroscience Potentials, Non-U.S. Support, Pain/chemically Adult Somatosensory Male Gov't AND Hand Fibers/physiology Magnetoencephalography Research Humans Nerve Nociceptors/physiology Somatosensory/physiology Capsaicin Plasticity/*physiology}, language = {eng}, lr = {20041117}, mhda = {2001/04/21 10:01}, month = Feb, number = 3, own = {NLM}, pages = {195-8}, pmid = {11165440}, pst = {ppublish}, pt = {Journal Article}, pubm = {Print}, so = {Neurosci Lett 2001 Feb;298(3):195-8.}, stat = {MEDLINE}, timestamp = {2006-05-30T01:06:19.000+0200}, title = {Functional reorganization of the human primary somatosensory cortex after acute pain demonstrated by magnetoencephalography.}, volume = 298, year = 2001 }