%0 Journal Article %1 Ridley05122003 %A Ridley, Anne J. %A Schwartz, Martin A. %A Burridge, Keith %A Firtel, Richard A. %A Ginsberg, Mark H. %A Borisy, Gary %A Parsons, J. Thomas %A Horwitz, Alan Rick %D 2003 %J Science %K mechanism migration phd review %N 5651 %P 1704--1709 %R 10.1126/science.1092053 %T Cell Migration: Integrating Signals from Front to Back %U http://www.sciencemag.org/content/302/5651/1704.abstract %V 302 %X Cell migration is a highly integrated multistep process that orchestrates embryonic morphogenesis; contributes to tissue repair and regeneration; and drives disease progression in cancer, mental retardation, atherosclerosis, and arthritis. The migrating cell is highly polarized with complex regulatory pathways that spatially and temporally integrate its component processes. This review describes the mechanisms underlying the major steps of migration and the signaling pathways that regulate them, and outlines recent advances investigating the nature of polarity in migrating cells and the pathways that establish it.

@article{Ridley05122003, abstract = {Cell migration is a highly integrated multistep process that orchestrates embryonic morphogenesis; contributes to tissue repair and regeneration; and drives disease progression in cancer, mental retardation, atherosclerosis, and arthritis. The migrating cell is highly polarized with complex regulatory pathways that spatially and temporally integrate its component processes. This review describes the mechanisms underlying the major steps of migration and the signaling pathways that regulate them, and outlines recent advances investigating the nature of polarity in migrating cells and the pathways that establish it.}, added-at = {2013-04-29T14:43:17.000+0200}, author = {Ridley, Anne J. and Schwartz, Martin A. and Burridge, Keith and Firtel, Richard A. and Ginsberg, Mark H. and Borisy, Gary and Parsons, J. Thomas and Horwitz, Alan Rick}, biburl = {https://www.bibsonomy.org/bibtex/2917560de183108deab9112b3d9c4cf7a/bkoch}, description = {Cell Migration: Integrating Signals from Front to Back}, doi = {10.1126/science.1092053}, eprint = {http://www.sciencemag.org/content/302/5651/1704.full.pdf}, interhash = {e182c175a1050c223e488db1995bb4c1}, intrahash = {917560de183108deab9112b3d9c4cf7a}, journal = {Science}, keywords = {mechanism migration phd review}, number = 5651, pages = {1704--1709}, timestamp = {2013-04-29T14:43:17.000+0200}, title = {Cell Migration: Integrating Signals from Front to Back}, url = {http://www.sciencemag.org/content/302/5651/1704.abstract}, volume = 302, year = 2003 }