%0 Journal Article %1 Busetto2013Nearoptimal %A Busetto, Alberto G. %A Hauser, Alain %A Krummenacher, Gabriel %A Sunnaker, Mikael %A Dimopoulos, Sotiris %A Ong, Cheng S. %A Stelling, Jörg %A Buhmann, Joachim M. %D 2013 %I Oxford University Press %J Bioinformatics %K experimental-design model-selection systems-biology %N 20 %P 2625--2632 %R 10.1093/bioinformatics/btt436 %T Near-optimal experimental design for model selection in systems biology %U http://dx.doi.org/10.1093/bioinformatics/btt436 %V 29 %X Motivation: Biological systems are understood through iterations of modeling and experimentation. Not all experiments, however, are equally valuable for predictive modeling. This study introduces an efficient method for experimental design aimed at selecting dynamical models from data. Motivated by biological applications, the method enables the design of crucial experiments: it determines a highly informative selection of measurement readouts and time points.

@article{Busetto2013Nearoptimal, abstract = {Motivation: Biological systems are understood through iterations of modeling and experimentation. Not all experiments, however, are equally valuable for predictive modeling. This study introduces an efficient method for experimental design aimed at selecting dynamical models from data. Motivated by biological applications, the method enables the design of crucial experiments: it determines a highly informative selection of measurement readouts and time points.}, added-at = {2018-12-02T16:09:07.000+0100}, author = {Busetto, Alberto G. and Hauser, Alain and Krummenacher, Gabriel and Sunn\r{a}ker, Mikael and Dimopoulos, Sotiris and Ong, Cheng S. and Stelling, J\"{o}rg and Buhmann, Joachim M.}, biburl = {https://www.bibsonomy.org/bibtex/221aed9b8d69357080f44af1f5bd0f47c/karthikraman}, citeulike-article-id = {12540606}, citeulike-linkout-0 = {http://dx.doi.org/10.1093/bioinformatics/btt436}, citeulike-linkout-1 = {http://bioinformatics.oxfordjournals.org/content/early/2013/08/24/bioinformatics.btt436.abstract}, citeulike-linkout-2 = {http://bioinformatics.oxfordjournals.org/content/early/2013/08/24/bioinformatics.btt436.full.pdf}, citeulike-linkout-3 = {http://view.ncbi.nlm.nih.gov/pubmed/23900189}, citeulike-linkout-4 = {http://www.hubmed.org/display.cgi?uids=23900189}, day = 15, doi = {10.1093/bioinformatics/btt436}, interhash = {e5478bfa25d9466b8039c73c918e3aee}, intrahash = {21aed9b8d69357080f44af1f5bd0f47c}, issn = {1460-2059}, journal = {Bioinformatics}, keywords = {experimental-design model-selection systems-biology}, month = oct, number = 20, pages = {2625--2632}, pmid = {23900189}, posted-at = {2013-09-05 13:52:22}, priority = {2}, publisher = {Oxford University Press}, timestamp = {2018-12-02T16:09:07.000+0100}, title = {Near-optimal experimental design for model selection in systems biology}, url = {http://dx.doi.org/10.1093/bioinformatics/btt436}, volume = 29, year = 2013 }