%0 Journal Article %1 huang2017advances %A Huang, Boyuan %A Zhang, Hongbo %A Gu, Lijuan %A Ye, Bainxin %A Jian, Zhihong %A Stary, Creed %A Xiong, Xiaoxing %D 2017 %J Journal of Immunology Research %K cancer fulltext glioblastoma immunotherapy therapy %P 11 %T Advances in Immunotherapy for Glioblastoma Multiforme %U https://doi.org/10.1155/2017/3597613 %V 2017 %X Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor in adults. Patients with GBM have poor outcomes, even with the current gold-standard first-line treatment: maximal safe resection combined with radiotherapy and temozolomide chemotherapy. Accumulating evidence suggests that advances in antigen-specific cancer vaccines and immune checkpoint blockade in other advanced tumors may provide an appealing promise for immunotherapy in glioma. The future of therapy for GBM will likely incorporate a combinatorial, personalized approach, including current conventional treatments, active immunotherapeutics, plus agents targeting immunosuppressive checkpoints.

@article{huang2017advances, abstract = {Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor in adults. Patients with GBM have poor outcomes, even with the current gold-standard first-line treatment: maximal safe resection combined with radiotherapy and temozolomide chemotherapy. Accumulating evidence suggests that advances in antigen-specific cancer vaccines and immune checkpoint blockade in other advanced tumors may provide an appealing promise for immunotherapy in glioma. The future of therapy for GBM will likely incorporate a combinatorial, personalized approach, including current conventional treatments, active immunotherapeutics, plus agents targeting immunosuppressive checkpoints.}, added-at = {2017-04-17T17:28:55.000+0200}, author = {Huang, Boyuan and Zhang, Hongbo and Gu, Lijuan and Ye, Bainxin and Jian, Zhihong and Stary, Creed and Xiong, Xiaoxing}, biburl = {https://www.bibsonomy.org/bibtex/26ab9b81a6bdb0f3365d4bd4b82e48384/marcsaric}, description = {Advances in Immunotherapy for Glioblastoma Multiforme}, interhash = {f73b1619dc863244f7b6542dd887e949}, intrahash = {6ab9b81a6bdb0f3365d4bd4b82e48384}, journal = {Journal of Immunology Research}, keywords = {cancer fulltext glioblastoma immunotherapy therapy}, pages = 11, timestamp = {2017-10-07T23:09:37.000+0200}, title = {Advances in Immunotherapy for Glioblastoma Multiforme}, url = {https://doi.org/10.1155/2017/3597613}, volume = 2017, year = 2017 }