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Synthesis of trans-1,3-diaryl-2-(5-methylisoxazol-3-yl)-2,3-dihydro-1H-naphtho1,2- e1,3oxazines via bismuth(III)-catalyzed one-pot pseudo-four component reaction

, , , , , , and . MOLECULAR DIVERSITY, 16 (4): 727-735 (November 2012)
DOI: {10.1007/s11030-012-9408-8}

Abstract

An expeditious, straightforward and efficient synthesis of diversely naphtho1,2-e1,3oxazines via one-pot condensation reaction of beta- naphthol, 3-amino-5-methylisoxazole and arylaldehydes catalyzed by bismuth(III) trifluoromethanesulfonate is described. The reaction preferentially afforded 1,3-trans oxazines.

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