A new immunosensor integrated to a flow system has been developed. It is based on magnetic immunoparticles immobilized on a solid-state transducer using a magnetic field. The described technique renews the immunoparticles reproducibly for each analysis allowing a good measurement precision. The developed experimental approach permits the implementation of an automated immunoassay that is quick (analytical cycle < 30 min) and sensitive in the micromolar concentration range. The system was applied to the determination of rabbit immunoglobulin G as an analyte model.
%0 Journal Article
%1 citeulike:574182
%A Solé, S.
%A Alegret, S.
%A Céspedes, F.
%A Fàbregas, E.
%A Díez-Caballero, T.
%C Departament de Química, Universitat Autònoma de Barcelona, Bellaterra, Catalonia, Spain.
%D 1998
%J Analytical Chemistry
%K fia electrochemistry immunoelectrode
%N 8
%P 1462--1467
%R 10.1021/ac970441+ S0003-2700(97)00441-1
%T Flow injection immunoanalysis based on a magnetoimmunosensor system.
%U http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9569757
%V 70
%X A new immunosensor integrated to a flow system has been developed. It is based on magnetic immunoparticles immobilized on a solid-state transducer using a magnetic field. The described technique renews the immunoparticles reproducibly for each analysis allowing a good measurement precision. The developed experimental approach permits the implementation of an automated immunoassay that is quick (analytical cycle < 30 min) and sensitive in the micromolar concentration range. The system was applied to the determination of rabbit immunoglobulin G as an analyte model.
@article{citeulike:574182,
abstract = {A new immunosensor integrated to a flow system has been developed. It is based on magnetic immunoparticles immobilized on a solid-state transducer using a magnetic field. The described technique renews the immunoparticles reproducibly for each analysis allowing a good measurement precision. The developed experimental approach permits the implementation of an automated immunoassay that is quick (analytical cycle < 30 min) and sensitive in the micromolar concentration range. The system was applied to the determination of rabbit immunoglobulin G as an analyte model.},
added-at = {2006-07-07T01:10:50.000+0200},
address = {Departament de Química, Universitat Autònoma de Barcelona, Bellaterra, Catalonia, Spain.},
author = {Solé, S. and Alegret, S. and Céspedes, F. and Fàbregas, E. and Díez-Caballero, T.},
biburl = {https://www.bibsonomy.org/bibtex/204d46eee50bdfc7cb675a5d799537418/biblio24},
citeulike-article-id = {574182},
doi = {10.1021/ac970441+ S0003-2700(97)00441-1},
interhash = {eecf27e0c926cd41f75907ff22506b01},
intrahash = {04d46eee50bdfc7cb675a5d799537418},
issn = {0003-2700},
journal = {Analytical Chemistry},
keywords = {fia electrochemistry immunoelectrode},
month = {April},
number = 8,
pages = {1462--1467},
priority = {2},
timestamp = {2006-07-07T01:10:50.000+0200},
title = {Flow injection immunoanalysis based on a magnetoimmunosensor system.},
url = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve\&db=pubmed\&dopt=Abstract\&list_uids=9569757},
volume = 70,
year = 1998
}