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Cell migration in 3D matrix

, und . Current Opinion in Cell Biology, 17 (5): 524--532 (2005)Cell-to-cell contact and extracellular matrix.
DOI: 10.1016/j.ceb.2005.08.015

Zusammenfassung

The ability of cells to migrate within the extracellular matrix and to remodel it depends as much on the physical and biochemical characteristics of a particular matrix as on cellular properties. Analyzing the different modes of migration of cells in matrices, and how cells switch between these modes, is vital for understanding a variety of physiological and pathological processes. Recent work provides new insights, but also raises some debates about the mechanisms and regulation of cell migration in three-dimensional matrices.

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Cell migration in 3D matrix

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