Intramuscular botulinum toxin type A (BT-A) has been shown to reduce spasticity and to improve gait in children with cerebral palsy. To determine whether the efficacy of BT-A may be enhanced by electrical stimulation, as suggested in focal dystonia or in adult spastic patients, 12 children with dynamic foot equinus deformity were randomly assigned to two groups in a blinded, clinically controlled trial. Intramuscular BT-A into calf muscles was followed by adjuvant electrical stimulation in Group A (n = 6) but not in Group B (n = 6). Clinical assessment and instrumented gait analysis were performed before and 1, 3, and 6 months after treatment. The combined treatment of BT-A and electrical stimulation was not superior to BT-A alone. For all patients, improvement of the clinical and gait variables occurred at 1 and 3 months after BT-A injection.
%0 Journal Article
%1 Detrembleur2002
%A Detrembleur, C.
%A Lejeune, T. M.
%A Renders, A.
%A Bergh, P. Y K Van Den
%D 2002
%J Mov Disord
%K Botulinum Toxin Type A; Cerebral Palsy; Child; Child, Preschool; Electric Stimulation Therapy; Electromyography; Equinus Deformity; Female; Gait; Humans; Male; Neuromuscular Agents; Random Allocation; Severity of Illness Index
%N 1
%P 162--169
%T Botulinum toxin and short-term electrical stimulation in the treatment of equinus in cerebral palsy.
%V 17
%X Intramuscular botulinum toxin type A (BT-A) has been shown to reduce spasticity and to improve gait in children with cerebral palsy. To determine whether the efficacy of BT-A may be enhanced by electrical stimulation, as suggested in focal dystonia or in adult spastic patients, 12 children with dynamic foot equinus deformity were randomly assigned to two groups in a blinded, clinically controlled trial. Intramuscular BT-A into calf muscles was followed by adjuvant electrical stimulation in Group A (n = 6) but not in Group B (n = 6). Clinical assessment and instrumented gait analysis were performed before and 1, 3, and 6 months after treatment. The combined treatment of BT-A and electrical stimulation was not superior to BT-A alone. For all patients, improvement of the clinical and gait variables occurred at 1 and 3 months after BT-A injection.
@article{Detrembleur2002,
abstract = {Intramuscular botulinum toxin type A (BT-A) has been shown to reduce spasticity and to improve gait in children with cerebral palsy. To determine whether the efficacy of BT-A may be enhanced by electrical stimulation, as suggested in focal dystonia or in adult spastic patients, 12 children with dynamic foot equinus deformity were randomly assigned to two groups in a blinded, clinically controlled trial. Intramuscular BT-A into calf muscles was followed by adjuvant electrical stimulation in Group A (n = 6) but not in Group B (n = 6). Clinical assessment and instrumented gait analysis were performed before and 1, 3, and 6 months after treatment. The combined treatment of BT-A and electrical stimulation was not superior to BT-A alone. For all patients, improvement of the clinical and gait variables occurred at 1 and 3 months after BT-A injection.},
added-at = {2014-07-19T19:18:52.000+0200},
author = {Detrembleur, C. and Lejeune, T. M. and Renders, A. and Bergh, P. Y K Van Den},
biburl = {https://www.bibsonomy.org/bibtex/21eea69997a00a97e32d75389db74d884/ar0berts},
groups = {public},
interhash = {ab8fbca5afca7bf1362a19d67961ef59},
intrahash = {1eea69997a00a97e32d75389db74d884},
journal = {Mov Disord},
keywords = {Botulinum Toxin Type A; Cerebral Palsy; Child; Child, Preschool; Electric Stimulation Therapy; Electromyography; Equinus Deformity; Female; Gait; Humans; Male; Neuromuscular Agents; Random Allocation; Severity of Illness Index},
month = Jan,
number = 1,
pages = {162--169},
pii = {10.1002/mds.1282},
pmid = {11835456},
timestamp = {2014-07-19T19:18:52.000+0200},
title = {Botulinum toxin and short-term electrical stimulation in the treatment of equinus in cerebral palsy.},
username = {ar0berts},
volume = 17,
year = 2002
}