An assumption-free automatic check of medical images for potentially overseen
anomalies would be a valuable assistance for a radiologist. Deep learning and
especially Variational Auto-Encoders (VAEs) have shown great potential in the
unsupervised learning of data distributions. In principle, this allows for such
a check and even the localization of parts in the image that are most
suspicious. Currently, however, the reconstruction-based localization by design
requires adjusting the model architecture to the specific problem looked at
during evaluation. This contradicts the principle of building assumption-free
models. We propose complementing the localization part with a term derived from
the Kullback-Leibler (KL)-divergence. For validation, we perform a series of
experiments on FashionMNIST as well as on a medical task including >1000
healthy and >250 brain tumor patients. Results show that the proposed formalism
outperforms the state of the art VAE-based localization of anomalies across
many hyperparameter settings and also shows a competitive max performance.
Description
Unsupervised Anomaly Localization using Variational Auto-Encoders
%0 Generic
%1 zimmerer2019unsupervised
%A Zimmerer, David
%A Isensee, Fabian
%A Petersen, Jens
%A Kohl, Simon
%A Maier-Hein, Klaus
%D 2019
%K cs.CV cs.LG stat.ML
%T Unsupervised Anomaly Localization using Variational Auto-Encoders
%U http://arxiv.org/abs/1907.02796
%X An assumption-free automatic check of medical images for potentially overseen
anomalies would be a valuable assistance for a radiologist. Deep learning and
especially Variational Auto-Encoders (VAEs) have shown great potential in the
unsupervised learning of data distributions. In principle, this allows for such
a check and even the localization of parts in the image that are most
suspicious. Currently, however, the reconstruction-based localization by design
requires adjusting the model architecture to the specific problem looked at
during evaluation. This contradicts the principle of building assumption-free
models. We propose complementing the localization part with a term derived from
the Kullback-Leibler (KL)-divergence. For validation, we perform a series of
experiments on FashionMNIST as well as on a medical task including >1000
healthy and >250 brain tumor patients. Results show that the proposed formalism
outperforms the state of the art VAE-based localization of anomalies across
many hyperparameter settings and also shows a competitive max performance.
@misc{zimmerer2019unsupervised,
abstract = {An assumption-free automatic check of medical images for potentially overseen
anomalies would be a valuable assistance for a radiologist. Deep learning and
especially Variational Auto-Encoders (VAEs) have shown great potential in the
unsupervised learning of data distributions. In principle, this allows for such
a check and even the localization of parts in the image that are most
suspicious. Currently, however, the reconstruction-based localization by design
requires adjusting the model architecture to the specific problem looked at
during evaluation. This contradicts the principle of building assumption-free
models. We propose complementing the localization part with a term derived from
the Kullback-Leibler (KL)-divergence. For validation, we perform a series of
experiments on FashionMNIST as well as on a medical task including >1000
healthy and >250 brain tumor patients. Results show that the proposed formalism
outperforms the state of the art VAE-based localization of anomalies across
many hyperparameter settings and also shows a competitive max performance.},
added-at = {2020-12-19T12:16:16.000+0100},
author = {Zimmerer, David and Isensee, Fabian and Petersen, Jens and Kohl, Simon and Maier-Hein, Klaus},
biburl = {https://www.bibsonomy.org/bibtex/225fdb6063c472635406703288367fdad/aerover},
description = {Unsupervised Anomaly Localization using Variational Auto-Encoders},
interhash = {f58be860120aac5f9d330a06fbfc4c3f},
intrahash = {25fdb6063c472635406703288367fdad},
keywords = {cs.CV cs.LG stat.ML},
note = {cite arxiv:1907.02796},
timestamp = {2021-01-17T01:33:27.000+0100},
title = {Unsupervised Anomaly Localization using Variational Auto-Encoders},
url = {http://arxiv.org/abs/1907.02796},
year = 2019
}