%0 Journal Article %1 uma_nath_u_2021_4718157 %A U, Uma Nath %A R, Ravi. %A Ganapathy, Sundara %A Prasanth, Lal %D 2021 %J World Journal of Biology Pharmacy and Health Sciences %K Cancer %N 3 %P 033-037 %R 10.30574/wjbphs.2021.5.3.0110 %T In vitro anticancer activity of Astaxanthin %U https://wjbphs.com/content/vitro-anticancer-activity-astaxanthin %V 5 %X This study was designed to determine the in vitro anticancer potential of the Astaxanthin isolated from shrimp shell waste (ETC) against Ehrlich Ascites Carcinoma (EAC) induced cancer in swiss albino mice. The anticancer activity was assessed using in vitro cytotoxicAity, mean survival time, tumor volume and hematological studies. The reliable criteria for evaluating the potential of any anticancer agent is the prolongation of lifespan of the animal and decrease in WBC count of blood. The high dose of ETC (200 mg/kg, orally) significantly reduced the tumor growth which was demonstrated by increased lifespan of the mice and restoration of hematological parameters. ETC was also found to be cytotoxic in the in vitro parameter which shows that ETC possesses significant anticancer potential.

@article{uma_nath_u_2021_4718157, abstract = {This study was designed to determine the in vitro anticancer potential of the Astaxanthin isolated from shrimp shell waste (ETC) against Ehrlich Ascites Carcinoma (EAC) induced cancer in swiss albino mice. The anticancer activity was assessed using in vitro cytotoxicAity, mean survival time, tumor volume and hematological studies. The reliable criteria for evaluating the potential of any anticancer agent is the prolongation of lifespan of the animal and decrease in WBC count of blood. The high dose of ETC (200 mg/kg, orally) significantly reduced the tumor growth which was demonstrated by increased lifespan of the mice and restoration of hematological parameters. ETC was also found to be cytotoxic in the in vitro parameter which shows that ETC possesses significant anticancer potential.}, added-at = {2021-04-25T08:37:26.000+0200}, author = {U, Uma Nath and R, Ravi. and Ganapathy, Sundara and Prasanth, Lal}, biburl = {https://www.bibsonomy.org/bibtex/230d793c77c59a09d6e6ac1ac93bdcee3/wjbphsjournal}, doi = {10.30574/wjbphs.2021.5.3.0110}, interhash = {b2ec8b9eb8476b2b6ee0489962408060}, intrahash = {30d793c77c59a09d6e6ac1ac93bdcee3}, issn = {2582-5542}, journal = {{World Journal of Biology Pharmacy and Health Sciences}}, keywords = {Cancer}, month = apr, number = 3, pages = {033-037}, timestamp = {2021-04-25T08:37:26.000+0200}, title = {In vitro anticancer activity of Astaxanthin}, url = {https://wjbphs.com/content/vitro-anticancer-activity-astaxanthin}, volume = 5, year = 2021 }