Summary: DataBiNS is a custom-designed BioMoby Web Service workflow
that integrates non-synonymous coding single nucleotide polymorphisms
(nsSNPs) data with structure/function and pathway data for the relevant
protein. A KEGG Pathway Identifier representing a specific human
biological pathway initializes the DataBiNS workflow. The workflow
retrieves a list of publications, gene ontology annotations and nsSNP
information for each gene involved in the biological pathway. Manual
inspection of output data from several trial runs confirms that all
expected information is appropriately retrieved by the workflow services.
The use of an automated BioMoby workflow, rather than manual surfing',
to retrieve the necessary data, significantly reduces the effort
required for functional interpretation of SNP data, and thus encourages
more speculative investigation. Moreover, the modular nature of the
individual BioMoby Services enables fine-grained reusing of each
service in other workflows, thus reducing the effort required to
achieve similar investigations in the future. Availability: The
workflow is freely available as a Taverna SCUFL XML document at the
iCAPTURE Centre web site, http://www.mrl.ubc.ca/who/who_bios_scott_tebbutt.shtml.
Contact: stebbutt@mrl.ubc.ca Supplementary information: Additional
information, including test result data, is available from the iCAPTURE
Centre web site (see above).
%0 Journal Article
%1 Song2007
%A Song, Young C.
%A Kawas, Edward
%A Good, Ben M.
%A Wilkinson, Mark D.
%A Tebbutt, Scott J.
%D 2007
%J Bioinformatics
%K bioinformatics biomoby services taverna web
%N 6
%P 780--782
%R 10.1093/bioinformatics/btl648
%T DataBiNS: a BioMoby-based data-mining workflow for biological pathways
and non-synonymous SNPs
%U http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=retrieve&db=pubmed&list_uids=17237074&dopt=Abstract
%V 23
%X Summary: DataBiNS is a custom-designed BioMoby Web Service workflow
that integrates non-synonymous coding single nucleotide polymorphisms
(nsSNPs) data with structure/function and pathway data for the relevant
protein. A KEGG Pathway Identifier representing a specific human
biological pathway initializes the DataBiNS workflow. The workflow
retrieves a list of publications, gene ontology annotations and nsSNP
information for each gene involved in the biological pathway. Manual
inspection of output data from several trial runs confirms that all
expected information is appropriately retrieved by the workflow services.
The use of an automated BioMoby workflow, rather than manual surfing',
to retrieve the necessary data, significantly reduces the effort
required for functional interpretation of SNP data, and thus encourages
more speculative investigation. Moreover, the modular nature of the
individual BioMoby Services enables fine-grained reusing of each
service in other workflows, thus reducing the effort required to
achieve similar investigations in the future. Availability: The
workflow is freely available as a Taverna SCUFL XML document at the
iCAPTURE Centre web site, http://www.mrl.ubc.ca/who/who_bios_scott_tebbutt.shtml.
Contact: stebbutt@mrl.ubc.ca Supplementary information: Additional
information, including test result data, is available from the iCAPTURE
Centre web site (see above).
@article{Song2007,
abstract = {Summary: DataBiNS is a custom-designed BioMoby Web Service workflow
that integrates non-synonymous coding single nucleotide polymorphisms
(nsSNPs) data with structure/function and pathway data for the relevant
protein. A KEGG Pathway Identifier representing a specific human
biological pathway initializes the DataBiNS workflow. The workflow
retrieves a list of publications, gene ontology annotations and nsSNP
information for each gene involved in the biological pathway. Manual
inspection of output data from several trial runs confirms that all
expected information is appropriately retrieved by the workflow services.
The use of an automated BioMoby workflow, rather than manual surfing',
to retrieve the necessary data, significantly reduces the effort
required for functional interpretation of SNP data, and thus encourages
more speculative investigation. Moreover, the modular nature of the
individual BioMoby Services enables fine-grained reusing of each
service in other workflows, thus reducing the effort required to
achieve similar investigations in the future. Availability: The
workflow is freely available as a Taverna SCUFL XML document at the
iCAPTURE Centre web site, http://www.mrl.ubc.ca/who/who_bios_scott_tebbutt.shtml.
Contact: stebbutt@mrl.ubc.ca Supplementary information: Additional
information, including test result data, is available from the iCAPTURE
Centre web site (see above).},
added-at = {2007-05-04T05:44:34.000+0200},
author = {Song, Young C. and Kawas, Edward and Good, Ben M. and Wilkinson, Mark D. and Tebbutt, Scott J.},
biburl = {https://www.bibsonomy.org/bibtex/2371f685ae581b27d05c65062f9905ee6/p_ansell},
day = 24,
description = {Bioinformatics Workflow Systems},
doi = {10.1093/bioinformatics/btl648},
interhash = {e423375b06ebd9fbc7cb0ff84b1bac26},
intrahash = {371f685ae581b27d05c65062f9905ee6},
journal = {Bioinformatics},
keywords = {bioinformatics biomoby services taverna web},
month = Jan,
number = 6,
owner = {peter},
pages = {780--782},
pdf = {Song2007.pdf},
timestamp = {2007-05-04T05:44:37.000+0200},
title = {DataBiNS: a BioMoby-based data-mining workflow for biological pathways
and non-synonymous SNPs},
url = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=retrieve&db=pubmed&list_uids=17237074&dopt=Abstract},
volume = 23,
year = 2007
}