%0 Journal Article %1 citeulike:500548 %A Smith, Richard S. %A Curtiss, Linda K. %A Koduri, Kanaka R. %A Witztum, Joseph L. %A Young, Stephen G. %D 1994 %J United States Patent %K patent apob %T DNA encoding recombinant lipoprotein antigens %V 5786206 %X Methods and compositions are described for determining the level of low density lipoproteins (LDL) in plasma. Native apoprotein B-100 (apo B-100) present in LDL particles is immunologically mimicked by a polypeptide of the invention. A polypeptide includes an amino acid residue sequence corresponding to a pan epitope region of the target apoprotein. A preferred polypeptide is a fusion protein that simultaneously mimics native apo B-100 and native apo A-I. Improved assay systems and methods for determining HDL and LDL levels in a body fluid sample are also described.

@article{citeulike:500548, abstract = {Methods and compositions are described for determining the level of low density lipoproteins (LDL) in plasma. Native apoprotein B-100 (apo B-100) present in LDL particles is immunologically mimicked by a polypeptide of the invention. A polypeptide includes an amino acid residue sequence corresponding to a pan epitope region of the target apoprotein. A preferred polypeptide is a fusion protein that simultaneously mimics native apo B-100 and native apo A-I. Improved assay systems and methods for determining HDL and LDL levels in a body fluid sample are also described.}, added-at = {2006-07-07T01:10:50.000+0200}, author = {Smith, Richard S. and Curtiss, Linda K. and Koduri, Kanaka R. and Witztum, Joseph L. and Young, Stephen G.}, biburl = {https://www.bibsonomy.org/bibtex/23db618752e985290194723c6b256ee78/biblio24}, citeulike-article-id = {500548}, institution = {The Scripps Research Institute (LaJolla, CA)}, interhash = {3336ff92c4d307a01b1bfbcd8b8137e0}, intrahash = {3db618752e985290194723c6b256ee78}, journal = {United States Patent}, keywords = {patent apob}, month = {October}, priority = {2}, timestamp = {2006-07-07T01:10:50.000+0200}, title = {DNA encoding recombinant lipoprotein antigens}, volume = 5786206, year = 1994 }