%0 Journal Article %1 griffiths2003generaldiffusion %A Griffiths, R. C. %D 2003 %J Theoretical Population Biology %K Green_function age_of_allele diffusions review selection site_frequency_spectrum %N 2 %P 241 - 251 %R 10.1016/S0040-5809(03)00075-3 %T The frequency spectrum of a mutation, and its age, in a general diffusion model %U http://www.sciencedirect.com/science/article/B6WXD-4909DXR-1/2/670352ac096b44ff4906f0b7f24a123c %V 64 %X General formulae are derived for the probability density and expected age of a mutation of frequency x in a population, and similarly for a mutation with b copies in a sample of n genes. A general formula is derived for the frequency spectrum of a mutation in a sample. Variable population size models are included. Results are derived in two frameworks: diffusion process models for the frequency of the mutation; and birth and death process models. The coalescent structure within the mutant gene group and the non-mutant group is considered.

@article{griffiths2003generaldiffusion, abstract = {General formulae are derived for the probability density and expected age of a mutation of frequency x in a population, and similarly for a mutation with b copies in a sample of n genes. A general formula is derived for the frequency spectrum of a mutation in a sample. Variable population size models are included. Results are derived in two frameworks: diffusion process models for the frequency of the mutation; and birth and death process models. The coalescent structure within the mutant gene group and the non-mutant group is considered.}, added-at = {2010-07-30T18:55:21.000+0200}, author = {Griffiths, R. C.}, biburl = {https://www.bibsonomy.org/bibtex/2501b312b75abd264a4932894551bb1ad/peter.ralph}, description = {ScienceDirect - Theoretical Population Biology : The frequency spectrum of a mutation, and its age, in a general diffusion model}, doi = {10.1016/S0040-5809(03)00075-3}, interhash = {1732791a4faecf19406f401868a5fece}, intrahash = {501b312b75abd264a4932894551bb1ad}, issn = {0040-5809}, journal = {Theoretical Population Biology}, keywords = {Green_function age_of_allele diffusions review selection site_frequency_spectrum}, number = 2, pages = {241 - 251}, timestamp = {2010-07-30T18:55:21.000+0200}, title = {The frequency spectrum of a mutation, and its age, in a general diffusion model}, url = {http://www.sciencedirect.com/science/article/B6WXD-4909DXR-1/2/670352ac096b44ff4906f0b7f24a123c}, volume = 64, year = 2003 }