A novel mediator-free, non-enzymatic electrochemical sensor, based on a
graphene-Schottky junction, was fabricated for glucose detection. The sensor
offers a promising alternative to the conventional enzyme-catalyzed
electrochemical continuous glucose monitoring systems (CGM), as it overcomes
many of the drawbacks attributed to the enzymatic nature; namely,
irreversibility, drift, and interference with body fluids, which affect their
accuracy, reliability and longevity. Enhanced performance of the sensors is
demonstrated through the band interaction at the graphene-Schottky junction,
which yields stronger forward/reverse currents in response to 50 \muL glucose
drop. Under optimized conditions, the linear response of the sensor to glucose
concentration was valid in the range from 0 to 15 mmol/L with a detection limit
of 0.5 mmol/L. The results indicated that the proposed sensor provided a highly
sensitive, more facile method with good reproducibility for continuous glucose
detection.
Description
Non-Enzymatic Graphene-Based Biosensors for Continous Glucose Monitoring
%0 Generic
%1 serry2015nonenzymatic
%A Serry, Mohamed
%A Sakr, M. A.
%D 2015
%K Glucose continuous free glucose graphene mediator monitoring non-enzymatic sensor
%T Non-Enzymatic Graphene-Based Biosensors for Continous Glucose Monitoring
%U http://arxiv.org/abs/1509.01581
%X A novel mediator-free, non-enzymatic electrochemical sensor, based on a
graphene-Schottky junction, was fabricated for glucose detection. The sensor
offers a promising alternative to the conventional enzyme-catalyzed
electrochemical continuous glucose monitoring systems (CGM), as it overcomes
many of the drawbacks attributed to the enzymatic nature; namely,
irreversibility, drift, and interference with body fluids, which affect their
accuracy, reliability and longevity. Enhanced performance of the sensors is
demonstrated through the band interaction at the graphene-Schottky junction,
which yields stronger forward/reverse currents in response to 50 \muL glucose
drop. Under optimized conditions, the linear response of the sensor to glucose
concentration was valid in the range from 0 to 15 mmol/L with a detection limit
of 0.5 mmol/L. The results indicated that the proposed sensor provided a highly
sensitive, more facile method with good reproducibility for continuous glucose
detection.
@misc{serry2015nonenzymatic,
abstract = {A novel mediator-free, non-enzymatic electrochemical sensor, based on a
graphene-Schottky junction, was fabricated for glucose detection. The sensor
offers a promising alternative to the conventional enzyme-catalyzed
electrochemical continuous glucose monitoring systems (CGM), as it overcomes
many of the drawbacks attributed to the enzymatic nature; namely,
irreversibility, drift, and interference with body fluids, which affect their
accuracy, reliability and longevity. Enhanced performance of the sensors is
demonstrated through the band interaction at the graphene-Schottky junction,
which yields stronger forward/reverse currents in response to 50 {\mu}L glucose
drop. Under optimized conditions, the linear response of the sensor to glucose
concentration was valid in the range from 0 to 15 mmol/L with a detection limit
of 0.5 mmol/L. The results indicated that the proposed sensor provided a highly
sensitive, more facile method with good reproducibility for continuous glucose
detection.},
added-at = {2015-09-08T06:00:26.000+0200},
author = {Serry, Mohamed and Sakr, M. A.},
biburl = {https://www.bibsonomy.org/bibtex/25072a0e581d60bdce76e1c1f6e9500bd/mserry},
description = {Non-Enzymatic Graphene-Based Biosensors for Continous Glucose Monitoring},
interhash = {3360693d982f47973a2d13ef920d0edd},
intrahash = {5072a0e581d60bdce76e1c1f6e9500bd},
keywords = {Glucose continuous free glucose graphene mediator monitoring non-enzymatic sensor},
note = {cite arxiv:1509.01581},
timestamp = {2015-09-08T06:00:26.000+0200},
title = {Non-Enzymatic Graphene-Based Biosensors for Continous Glucose Monitoring},
url = {http://arxiv.org/abs/1509.01581},
year = 2015
}